Indianapolis Colts at Houston Texans odds, picks and predictions

Analyzing Sunday’s Indianapolis Colts at Houston Texans odds and lines, with expert NFL picks and predictions.

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The Indianapolis Colts (0-1) square off against the Houston Texans (0-1) in the battle of rookie quarterbacks Sunday. Kickoff from NRG Stadium is scheduled for 1 p.m. ET (FOX). Below, we analyze BetMGM Sportsbook’s lines around the Colts vs. Texans odds, and make our expert NFL picks and predictions.

The Colts lost 31-21 and failed to cover as 3.5-point underdogs against the Jacksonville Jaguars in rookie QB Anthony Richardson‘s debut. Indianapolis carried a 21-17 lead into the 4th quarter before giving up 14 unanswered points and dropping the game.

Richardson went 24-of-37 passing for 223 yards with a TD and an INT and had 10 carries for 40 yards and a TD. WR Michael Pittman Jr. caught 8 passes for 97 yards and a TD.

The Texas failed to cover as 9.5-point underdogs in a 25-9 loss to the Baltimore Ravens in QB C.J. Stroud‘s debut. Stroud went 28-of-44 passing for 242 yards through the air with 0 TD or INT and had 4 carries for 20 yards and a fumble.

It was a tough day all around for Houston as they failed to find the end zone. WR’s Nico Collins (6 receptions, 80 yards) and Robert Woods (6, 57) appeared to be Stroud’s favorite targets with each seeing double-digit targets.

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Colts at Texans odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 3 p.m. ET.

  • Moneyline (ML): Colts +100 (bet $100 to win $100) | Texans -120 (bet $120 to win $100)
  • Against the spread (ATS): Colts  +1 (-110) | Texans -1 (-110)
  • Over/Under (O/U): 39.5 (O: -110 | U: -110)

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Colts at Texans key injuries

Colts

  • OL Quenton Nelson (toe) questionable

Texans

  • LB Neville Hewitt (illness) questionable
  • WR John Metchie III (hamstring) questionable
  • Jalen Pitre (chest) questionable
  • OL Laremy Tunsil (knee) questionable
  • Jimmie Ward (hip) questionable

Colts at Texans picks and predictions

Prediction

Texans 21, Colts 17

Moneyline

BET TEXANS (-120).

It appeared that Richardson had to be a jack of all trades last week as the Colts forged forward with RB Jonathan Taylor on the PUP and mired in a contract dispute. While it seemed to work for a majority of the game, Indianapolis was unable to keep the steam late in the game. Expect the energy to be high in the Texans’ home opener and a bounce-back game from RB Dameon Pierce to carry them to victory.

Against the spread

BET TEXANS -1 (-110).

In this instance, a Texans win means a Texans cover — or at least a push. While Stroud did not particularly impress last week, his only big mistake was a fumble. In this battle of rookie QBs, who have been friends since high school, the home QB with a more grounded offense will lead his team to the win and cover.

Over/Under

LEAN UNDER 39.5 (-110).

Barring a standout game from one or both of these first-year QBs, the Under is looking likely. The Colts have not identified a lead RB in Taylor’s absence while the Texans will look to get Pierce going early after a slow outing against the Ravens last week. With each QB still settling into their respective offense, do not be surprised with sloppier play and fewer points.

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Indianapolis Colts at Houston Texans odds, picks and predictions

Analyzing Sunday’s Indianapolis Colts at Houston Texans Week 1 odds and lines, with expert NFL picks, predictions and best bets.

The Indianapolis Colts and Houston Texans open their seasons Sunday at NRG Stadium. Kickoff is set for 1 p.m. ET (CBS). Below, we analyze Tipico Sportsbook‘s lines around the Colts vs. Texans odds, and make our expert NFL picks and predictions.

The Colts finished the 2021 season with a 26-11 loss at the Jacksonville Jaguars in Week 18 as 14-point favorites that resulted in them missing the playoffs. Indianapolis then brought in QB Matt Ryan from the Atlanta Falcons to replace QB Carson Wentz under center.

Indianapolis is the favorite to win the AFC South at -135. Colts star RB Jonathan Taylor is the favorite to finish the regular season with the most rushing yards at +425 and co-favorite with Los Angeles Rams WR Cooper Kupp to win Offensive Player of the Year at +900.

Houston is clearly in a rebuild after only winning 4 games last season. However, the Texans covered the spread in 3 of their final 4 games, including a 41-29 win as 13.5-point underdogs vs. the Los Angeles Chargers in December.

Houston QB Davis Mills finished his rookie campaign with 16 TD and 10 INT. Houston is the favorite at +300 to finish with the worst record in the NFL.

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Colts at Texans odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 7:38 a.m. ET.

  • Money line (ML): Colts -340 (bet $340 to win $100) | Texans +270 (bet $100 to win $270)
  • Against the spread (ATS): Colts -7.5 (+100) | Texans +7.5 (-120)
  • Over/Under (O/U): 45.5 (O: -112 | U: -108)

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Colts at Texans key injuries

Colts

  • LB Shaquille Leonard (ankle) probable

Texans

  • None

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Colts at Texans picks and predictions

Prediction

Colts 28, Texans 21

Money line

PASS.

The Colts (-340) should win, but the price is too high to bet the money line. While Indianapolis is the better team, Houston showed at the end of last season that it is capable of upsetting big favorites.

Against the spread

Indianapolis has a better roster than Houston, but this will be Ryan’s first regular season game with the Colts. Mills has had the time to build chemistry with his receivers that Ryan hasn’t had.

Houston is undervalued in this spot considering its offense can build on the chemistry it flashed at the end of last season.

BET THE TEXANS +7.5 (-120).

Over/Under

The Under is 5-0 in the last 5 head-to-head meetings between these teams, but those were under different circumstances. Indianapolis’ offense should be much more productive with former MVP Ryan acting as signal-caller, while Houston’s offense should have drastically improved since the most recent head-to-head meeting last December.

BET OVER 45.5 (-112).

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Indianapolis Colts at Houston Texans odds, picks and prediction

Analyzing Sunday’s Indianapolis Colts at Houston Texans odds and lines, with expert NFL picks, predictions and best bets.

The Indianapolis Colts (6-6) will take on the Houston Texans (2-9) at NRG Stadium Sunday in Week 13. Kickoff is set for 1 p.m. ET. Below, we look at the Colts vs. Texans odds and lines, and make our best NFL picks, predictions and bets.

The Colts absolutely destroyed the QB Davis Mills-led Texans earlier in the season. RB Jonathan Taylor went for 145 yards on 14 carries while Davis Mills threw 2 interceptions.

The Texans should begin to look like a more competent side now with QB Tyrod Taylor healthy, although they did lose to the New York Jets in Week 12.

The Texans come into this game 5-6 against the spread (ATS) while the Colts are 7-5 ATS. Indianapolis is 3-2 straight up on the road while Houston is just 1-4 at home.

Colts at Texans odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 10 p.m. ET.

  • Money line: Colts -500 (bet $500 to win $100) | Texans +360 (bet $100 to win $360)
  • Against the spread (ATS): Colts -9.5 (-115) | Texans +9.5 (-105)
  • Over/Under (O/U): 44.5 (O: -105 | U: -115)

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Colts at Texans key injuries

Colts

  • DT DeForest Buckner (knee) questionable
  • TE Jack Doyle (knee) questionable
  • Andrew Sendejo (calf) questionable

Texans

  • WR Brandin Cooks (illness) questionable
  • DB Terrence Brooks (hamstring) out
  • RB David Johnson (illness, thigh) questionable
  • OL Justin McCray (concussion) out
  • DL DeMarcus Walker (hamstring) out
  • DL Jonathan Greenard (foot) questionable
  • DL Roy Lopez (illness) questionable

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Colts at Texans odds, lines, predictions and picks

Prediction

Colts 31, Texans 14

Money line

PASS on the money line.

This is a do-or-die scenario for the Colts — they must get the win, and I expect them to play like it. However, -500 odds still aren’t worth any wager, and neither is really the +360 on the Texans.

Against the spread

BET on the COLTS -9.5 (-115) despite the high spread. The Texans are coming off a 7-point loss to the Jets. This could be a good buy-low spot for them, but I wouldn’t trust Houston.

They rank 31st in opponents rushing yards per game which plays into a strength of the Colts. Taylor is leading the league in rushing yards and destroyed a weak Texans defensive line in their first meeting. He should continue that dominance.

The Colts have hit 31 points in four of their last five games. Their offense has been dynamic and I think it’ll once again prove far too much for Houston to handle.

Over/Under

“LEAN” to the OVER 44.5 (-105) as the Colts have an offense that’s been on fire as of late and it’s facing one of the league’s worst defenses.

On the flip side, there should be hope that Taylor, with another week under his belt, can produce offensively. Taylor should have the weapons to march down the field provided Cooks is able to suit up.

The Texans average 14.9 points per game, so with their inept defense, all they need to do is hit that amount.

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Indianapolis Colts at Houston Texans odds, picks and prediction

Previewing the Indianapolis Colts at Houston Texans Week 13 betting odds and lines, with NFL betting picks, tips and predictions.

The Indianapolis Colts (7-4) are in the midst of a fight for the AFC South crown and Sunday afternoon, they’ll visit a Houston Texans (4-7) team that has won three of its last four games. The Week 13 game will be held at NRG Stadium with kickoff at 1 p.m. ET. Below, we preview the Colts-Texans betting odds and lines and make our NFL picks and predictions.

Colts at Texans: Betting odds, spread and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Friday at 9:45 a.m. ET.

  • Money line: Colts -190 (bet $190 to win $100) | Texans +160 (bet $100 to win $160)
  • Against the spread/ATS: Colts -3.5 (-110) | Texans +3.5 (-110)
  • Over/Under: 50.5 (O: -110 | U: -110)

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Colts at Texans: Game notes

  • The Texans and Colts have split their last 10 meetings, with each team winning five games. The Colts have won two of the last three, however.
  • The Colts are 6-5 ATS this season, while the Texans are just 4-7.
  • In their last seven games against the Texans, the Colts are 6-1 ATS.
  • The Colts rank in the top 10 defensively in points allowed, passing yards and rushing yards allowed, and yards per play.
  • The total has gone Under in five of the Texans’ last six games at home.

Colts at Texans: Key injuries

Colts

  • QB Philip Rivers (toe) questionable
  • OT Anthony Castonzo (knee) questionable
  • LB Bobby Okereke (ankle) questionable

Texans

  • DT Ross Blacklock (illness) questionable
  • RB C.J. Prosise (illness) questionable
  • S Lonnie Johnson (knee) questionable

Colts at Texans: Odds, betting lines, predictions and picks

Prediction

Colts 24, Texans 21

Money line (?)

With as poorly as the Texans have played this year, this is still an evenly-matched game; however, it’ll be a tough one for Houston to win. With no WR Will Fuller or WR Kenny Stills, QB Deshaun Watson‘s weapons will be limited.

The Colts have an outstanding defense, particularly against the pass. They’ll hold Watson in check long enough and move the ball well on the ground against Houston’s 31st-ranked rush defense. Take the COLTS (-190) to win outright.

Against the spread (?)

The Texans have covered the spread in only four of their 11 games this season, most of which were as underdogs. They’ll keep this one close, though, thanks to the magic of Watson.

Take the TEXANS +3.5 (-110) to cover the spread and lose by three or fewer points. The Colts have a knack for blowing teams out – especially bad ones – but that won’t be the case here.

Over/Under (?)

The total has gone Under in six of the last eight games between these two teams. The Texans offense isn’t as explosive without Fuller and Stills, which will keep their scoring rate lower than usual.

The total of 50.5 is fairly high, so I’m taking the UNDER (-110) here.

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