The Houston Texans (1-2) aim to end their two-game losing skid as they take on the Buffalo Bills (2-1) on the road in Week 4. Kickoff is at 1 p.m. ET at Highmark Stadium. Below, we look at the Texans vs. Bills odds and lines; check back for our NFL picks and predictions.
Houston is coming off a 24-9 Thursday night loss to the Carolina Panthers. The Texans mustered only 193 yards of total offense and only 14 first downs, while giving up 407 yards to the Panthers. The Texans have lost two in a row after a season-opening 37-21 win over the Jacksonville Jaguars.
The Bills have won two in a row after losing 23-16 in Week 1 to the Pittsburgh Steelers. Their latest win was a 43-21 drubbing of the Washington Football Team. QB Josh Allen threw 4 touchdown passes in Week 3 and has 7 on the season.
Also see: All Week 4 odds and lines
Texans at Bills odds, spread and line
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Tuesday at 1:10 p.m. ET.
- Money line: Texans +750 (bet $100 to win $750) | Bills -1400 (bet $1,400 to win $100)
- Against the spread (ATS): Texans +16.5, -110 (bet $110 to win $100) | Bills -16.5, -110 (bet $110 to win $100)
- Total (O/U): 48.5, Over -105 (bet $105 to win $100) | Under -115 (bet $115 to win $100)
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2021 betting stats:
- ML: Texans 1-2 | Bills 2-1
- ATS: Texans 2-1 | Bills 2-1
- O/U: Texans 2-1 | Bills 1-2
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Texans at Bills head-to-head
The Texans and Bills last met in the playoffs following the 2019 season. Houston won 22-19.
They have faced each other 10 times including the playoffs and the Texans lead the all-time series 6-4. They won five of the last six meetings.
Allen started against the Texans in his rookie season in 2018, a 20-13 Texans win with Allen leaving the game due to injury.
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