New York Giants at New Orleans Saints odds, picks and prediction

Analyzing the New York Giants at New Orleans Saints Week 4 odds and lines, with expert NFL picks, predictions and best bets.

The New York Giants (0-3) and New Orleans Saints (2-1) meet at Caesars Superdome on Sunday in Week 4. Kickoff is scheduled for 1 p.m. ET. Below, we look at the Giants vs. Saints odds and lines, and make our best NFL picks, predictions and bets.

The Giants are winless like their roommates, the New York Jets, but they haven’t quite been hot garbage like the latter. The Giants lost a heartbreaker in Week 2 on Thursday in Washington, 30-29, and fell 17-14 at home to the Atlanta Falcons in Week 3. That’s two straight losses by a total of four points, so they’re getting close.

The Saints throttled the Green Bay Packers in Jacksonville in Week 1, 38-3, displaced due to Hurricane Ida. New Orleans split its next two games on the road, losing 26-7 at Carolina before picking up a 28-13 win at New England.

Ida wasn’t quite the disaster, thankfully, that Katrina was in 2005. However, it was still pretty devastating to the area. This will be its first game in front of the home fans in 2021, and since the second preseason game Aug. 23. The Under is 3-0 for the Saints.

Oddly enough, there was also a roof fire at Caesars Superdome last week, but that issue won’t derail this game.

Giants at Saints odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Thursday at 12:10 p.m. ET.

  • Money line: Giants +290 (bet $100 to win $290) | Saints -380 (bet $380 to win $100)
  • Against the spread (ATS): Giants +7.5 (-115) | Saints -7.5 (-107)
  • Over/Under (O/U): 41.5 (O: -108 | U: -112)

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Giants at Saints key injuries

Giants

  • RB Saquon Barkley (knee) questionable
  • WR Kenny Golladay (hip) questionable
  • LB Blake Martinez (knee) out
  • WR Sterling Shepard (hamstring) questionable
  • WR Darius Slayton (hamstring) questionable

Saints

  • OT Terron Armstead (elbow) questionable

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Giants at Saints odds, lines, predictions and picks

Prediction

Saints 30, Giants 16

Money line

The Saints (-380) are back home in the Crescent City, and it’s going to be an emotional return. In fact, the crowd would have been loud anyway, but they’ll be blowing out the lines after dealing with COVID restrictions, the hurricane, etc.

The winless Giants (+290) do not need any further obstacles, and they’re in a no-win situation here. However, you can’t risk nearly four times your potential return as that’s a poor long-term betting strategy.

AVOID, and look to the spread.

Against the spread

The SAINTS -7.5 (-107) are a much better play laying the points, but I’d much prefer a flat seven or six-and-a-half.

New Orleans is 0-1 SU/ATS as a favorite so far, while going 2-0 SU/ATS as an underdog. And the Giants +7.5 (-115) did cover in their only road game as an underdog.

However, I think all of that can be shaken up like an Etch-a-Sketch and forgotten. The Dome is going to be wild Sunday, and the G-Men don’t have a prayer against the Saints.

Over/Under

The OVER 41.5 (-108) is the lean, ever so slightly. It’s worth a small-unit wager as the Overs have been hard to come by for both sides. The Under is 2-1 for the G-Men, and 3-0 for the Saints, so playing the Over is against the grain.

But I think the Saints scratch out enough points in their NOLA return, and the Giants do at least have a functional offense, which will get them into the teens.

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