Arizona Diamondbacks at San Francisco Giants odds, picks and best bets

Previewing Friday’s Arizona Diamondbacks at San Francisco Giants sports betting odds and lines, with MLB betting picks, tips and best bets.

The Arizona Diamondbacks (14-24) and San Francisco Giants (18-20) dive into a weekend series with a 9:45 p.m. ET game on Friday at Oracle Park in Northern California. Below, we analyze the Diamondbacks-Giants MLB betting odds and lines, with picks and best bets.

Diamondbacks at Giants: Projected starting pitchers

RHP Taylor Clarke vs. LHP Tyler Anderson

Clarke is 1-0 with a 2.22 ERA and 0.95 WHIP in eight appearances (two starts) this season.

He is coming off a nice Aug. 30 outing against this same San Francisco squad (1 run in 5 IP) and is getting his 18th career start in this one. Of the 27-year-old’s 24 1/3 IP this season, nine have come in his last two — his two starts.

  • Plan on a four- or five-inning outing for Clarke. That exposes an Arizona relief corps (4.26 ERA) to some heavy lifting.
  • Clarke has benefited from a .130 opponent’s batting average on balls in play and opponents stranding 86.2 percent of their runners on base.

Anderson owns a 1-2 record with a 4.75 ERA and 1.39 WHIP through 36 IP.

  • The 30-year-old southpaw is making his third straight start against Arizona. The first (Aug. 22) went exceedingly well (three-hit shutout); the second (Aug. 28) was abysmal (10 base runners, 7 ER in 4 2/3 IP).
  • Owing to some control problems and allowing too many line drives, Anderson has allowed 4 ER or more in three of his last four starts.

Get some action on this game or any other matchup in the 2020 season with an MLB bet at BetMGM in NJ, IN, CO and WV. Bet now!

Diamondbacks at Giants: Key injuries

(Get the latest injury news here.)

Giants

  • Aramis Garcia (hip) out
  • OF Austin Slater (groin) out
  • OF Joey Rickard (elbow) out

Also see: BaseballHQ Fantasy Baseball

Diamondbacks at Giants: Odds, lines, picks and betting tips

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 1 p.m. ET.

Moneyline (ML)

The prices mask a would-be lean on San Francisco. PASS ON GIANTS -129.

New to sports betting? A winning $50 bet on the Giants returns a profit of $39.

Run line/Against the spread (ATS)

The Snakes are 2-5 over opening games of road sets this season. Arizona has been dreadful of late — the Diamondbacks come in having lost five in a row and 13 of their last 14. The Giants, meanwhile, have won three of their last four and 10 of their last 14. That stretch includes zero wins by one run. It also includes five wins in six tries against Arizona in August.

Shading the over and getting a solid tag, make a play on the GIANTS -1.5 (+150).

Over/Under (O/U)

A humid, breezy night mixes with a surging San Francisco lineup and two mediocre bullpens. And both starting pitchers have overcooked surface numbers. Run, don’t walk to the OVER 9 (-110) proposition on the last game of the night.

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