Detroit Lions at Arizona Cardinals odds, picks and predictions

Analyzing Sunday’s Detroit Lions at Arizona Cardinals odds and lines, with expert NFL picks and predictions.

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The Detroit Lions (1-1) are on the road in Week 3 taking on the Arizona Cardinals (1-1). Kickoff from State Farm Stadium is at 4:25 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Lions vs. Cardinals odds, and make our expert NFL picks and predictions.

The Lions, after a season-opening 26-20 overtime win over the LA Rams, lost 20-16 at home in Week 2 to the Tampa Bay Buccaneers, going 1-for-7 in the red zone and turning the ball over twice. They were 7.5-point favorites in the game.

The Cardinals blew out the Rams 41-10 in Week 2 behind QB Kyler Murray’s 3 TD passes and perfect 158.3 passer rating in the game. They were 1-point favorites in their home opener.

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Lions at Cardinals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Saturday at 9:21 p.m. ET.

  • Moneyline (ML): Lions -150 (bet $150 to win $100) | Cardinals +125 (bet $100 to win $125)
  • Against the spread (ATS): Lions -3 (-105) | Cardinals +3 (-115)
  • Over/Under (O/U): 51.5 (O: -110 | U: -110)

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Lions at Cardinals key injuries

Lions

  • LB Alex Anzalone (concussion) questionable
  • CB Terrion Arnold (illness) questionable
  • Graham Glasgow (knee) questionable
  • S Ifeatu Melifonwu (ankle) out
  • CB Ennis Rakestraw (hamstring) out
  • WR Isaiah Williams (abdomen) questionable

Cardinals

  • T Kelvin Beachum (hamstring) questionable
  • WR Greg Dortch (hamstring) questionable
  • DL Dante Stills (shoulder) questionable

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Lions at Cardinals picks and predictions

Prediction

Lions 30, Cardinals 24

Moneyline

The Cardinals have scored the 2nd-most points in the league so far and have been basically unstoppable offensively for 6 of the 8 quarters they have played.

Detroit is No. 2 in yards, but has struggled cashing in yards for touchdowns, averaging only 21 points per game.

But the Lions are great at defending running backs, which means Arizona’s James Conner will find it tough to keep the offense on schedule.

Detroit is susceptible to mobile QBs, and Murray has rushed for over 50 yards in both games this season so far.

Lions QB Jared Goff is 8-0 in his last 8 starts vs. the Cardinals with 14 TD passes and 3 rushing TDs. The Cardinals have not beaten Detroit since 2015.

And with Beachum perhaps missing the game, it means Lions DE Aidan Hutchinson, who had 4.5 sacks in the loss in Week 2, might line up against a 3rd-string tackle for the Cardinals.

The Cardinals had 5 sacks against the Rams last week, but the Rams played with a 3rd-string left tackle. Detroit has arguably the best tackle tandem in the league.

So the Lions probably will win this game. And while -150 odds aren’t terrible, the spread is a better bet.

PASS.

Against the spread

The Cardinals are 2-0 ATS so far this season. The Lions just haven’t gotten fully in rhythm offensively. They move the ball but haven’t scored TDs.

The defense is Arizona’s biggest question. They should be able to hang with the Lions in terms of points, but can they bottle up both RB David Montgomery and RB Jahmyr Gibbs? They struggled against Buffalo RB James Cook in Week 1.

BET LIONS -3 (-105).

Over/Under

The Over has hit in both of the Cardinals’ games this season.

The Lions went 1-for-7 in the red zone against Tampa. They won’t fail that many times against the Cardinals.

We know the Cardinals will score points. Can they score enough? This game should be a 1-score, high-scoring game.

BET OVER 51.5 (-110).

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Tampa Bay Buccaneers at Detroit Lions odds, picks and predictions

Analyzing Sunday’s Tampa Bay Buccaneers at Detroit Lions odds and lines, with expert NFL picks and predictions.

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The Detroit Lions (1-0) welcome the Tampa Bay Buccaneers (1-0) to Ford Field Sunday. Kickoff is set for 1 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Buccaneers vs. Lions odds, and make our expert NFL picks and predictions.

The Buccaneers, who won and covered in 2 of 3 preseason games, beat the Washington Commanders at home 37-20 Sunday, covering as a 4-point favorite. QB Baker Mayfield went off for 4 TDs and 289 yards. Two of those TD passes went to WR Mike Evans. A similar Buccaneers team went 8-2 against the spread (ATS) last season.

The Lions, who were 6-4 ATS at home a season ago, also won and covered in 2 of 3 preseason games. In Week 1 action, Detroit won 26-20 in OT over the LA Rams, covering as a 5.5-point home favorite. QB Jared Goff ended with 217 yards, a TD and an INT. RB David Montgomery rushed for 91 yards and a TD.

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Buccaneers at Lions odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Friday at 6:37 p.m. ET.

  • Moneyline (ML): Buccaneers +290 (bet $100 to win $290) | Lions -375 (bet $375 to win $100)
  • Against the spread (ATS): Buccaneers +7.5 (-110) | Lions -7.5 (-110)
  • Over/Under (O/U): 51.5 (O: -110 | U: -110)

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Buccaneers at Lions key injuries

Buccaneers

  • DE Marcus Davenport (groin) doubtful
  • OT Penei Sewell (ankle) questionable
  • WR Jameson Williams (ankle) questionable

Lions

  • OT Luke Goedeke (concussion) out
  • DE Logan Hall (foot) questionable
  • DT Calijah Kancey (calf) out
  • CB Zyon McCollum (concussion) questionable
  • S Antoine Winfield Jr. (unknown) out
  • DB Tykee Smith (illness) questionable

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Buccaneers at Lions picks and predictions

Prediction

Lions 27, Buccaneers 21

Moneyline

PASS.

There’s no value here.

The Lions have been among the more consistent teams over the last few seasons and should come out on top. While the Bucs could be worth a play as a sizable underdog, that wager is better used on the spread.

Against the spread

BET BUCCANEERS +7.5 (-110).

The Buccaneers were very profitable on the spread when on the road last season (8-2), and they showed their lofty potential in Week 1, throttling the Commanders. Mayfield looked consistent and took just 1 sack. He didn’t have a turnover either. The Bucs defense allowed just 161 passing yards too. They should be able to limit Goff.

The Lions looked vulnerable despite winning at home in Week 1. They allowed 17 second-half points and gave up 304 passing yards, which Mayfield will look to exploit as well. Considering Detriot’s pass weakness and the Bucs’ strength on the spread last year, take BUCCANEERS +7.5 (-110).

Over/Under

BET UNDER  51.5 (-110).

The Lions have a starting offensive lineman questionable while the Bucs will be a starter short on the line. The defensive lines may be able to take control of those weaknesses and get in the backfield, potentially haunting drives with tackles for loss and sacks.

The Lions were Under in Week 1, but play a fast pace which often lifts the total. This would’ve been the highest total in any Bucs game last season. The Bucs scored 37 in Week 1, but scored that many just once last season, so that’s not expected to be repeated. They held the Commanders to 20 last week.

Take UNDER 51.5 (-110).

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LA Rams at Detroit Lions odds, picks and predictions

Analyzing Sunday’s LA Rams at Detroit Lions odds and lines, with expert NFL picks and predictions.

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The penultimate game of Week 1 is a matchup between the LA Rams and Detroit Lions on Sunday Night Football. Kickoff from Ford Field in Detroit is set for 8:20 p.m. ET (NBC). Below, we analyze BetMGM Sportsbook’s lines around the Rams vs. Lions odds, and make our expert NFL picks and predictions.

The Rams come into the season after going 10-7 in 2023. Their campaign ended with a 24-23 loss to the Lions in the wild-card round in January, so they’re opening the 2024 season in the same place last season ended for them. QB Matthew Stafford, WR Cooper Kupp and WR Puka Nacua are all healthy for Week 1, though the defense will be missing DT Aaron Donald following his retirement in March.

The Lions reached the NFC Championship Game last season after beating the Rams and Tampa Bay Buccaneers in the first 2 rounds. The San Francisco 49ers beat them in the conference title game but they’re on track to be a contender in the NFC once again with QB Jared Goff, WR Amon-Ra St. Brown and DE Aidan Hutchinson all back.

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Rams at Lions odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 1:50 p.m. ET.

  • Moneyline (ML): Rams +185 (bet $100 to win $185) | Lions -225 (bet $225 to win $100)
  • Against the spread (ATS): Rams +4.5 (-110) | Lions -4.5 (-110)
  • Over/Under (O/U): 52.5 (O: -110 | U: -110)

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Rams at Lions key injuries

Rams

  • RT Rob Havenstein (ankle) questionable
  • TE Tyler Higbee (knee) out

Lions

  • S Ifeatu Melifonwu (ankle) doubtful
  • DT D.J. Reader (quadriceps) questionable

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Rams at Lions picks and predictions

Prediction

Lions 27, Rams 24

Moneyline

January’s meeting between the Rams and Lions came down to the wire, with Detroit pulling off a 1-point home win. The Rams are better equipped to challenge the Lions this season, but with their starting left tackle and cornerbacks missing, it could be a tall task to win outright Sunday.

PASS on the money line, as the Lions at -225 is not a price worth paying.

Against the spread

The Rams are 2-1 ATS in their last 3 meetings against the Lions, only failing to cover as 17-point favorites in 2021; they still won that game, 28-19. As good as the Lions were against the spread last season (14-6), the Rams weren’t far behind at 11-6-1 – 3rd-best in the NFL.

The Rams offense is loaded with talent and the defense is more well-rounded up front despite losing Donald. That’ll keep this game close, even on the road in a hostile environment. BET RAMS +4.5 (-110).

Over/Under

The total has gone Under in each of the last 3 meetings between these teams. After they combined for 38 points in the 1st half during January’s playoff game, they scored just 9 total points in the 2nd half, with no touchdowns.

As explosive as both of these offenses could be this season, Week 1 typically comes with some slow starts on that side of the ball, especially considering neither quarterback played in the preseason. BET UNDER 52.5 (-110).

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Pittsburgh Steelers at Detroit Lions odds, picks and predictions

Analyzing Saturday’s Pittsburgh Steelers at Detroit Lions odds and lines, with expert NFL picks and predictions.

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The Pittsburgh Steelers (0-2) visit the Detroit Lions (1-1) Saturday for both teams’ final preseason game. Kickoff from Ford Field is scheduled for 1 p.m. ET (NFL Network). Below, we analyze BetMGM Sportsbook’s lines around the Steelers vs. Lions odds, and make our expert NFL picks and predictions.

The Steelers fell 9-3 to the visiting Buffalo Bills last Saturday, failing to cover as 2.5-point favorites with the Under (38.5) easily cashing. QB Justin Fields went 11 of 17 for 92 yards, while veteran QB Russell Wilson went 8 of 10 for 47 yards. Neither of the potential starting QB’s were able to produce a touchdowns in the losing effort, but they didn’t turn the ball over either.

The Lions beat the Chiefs 24-23 last Saturday, winning outright as 9.5-point road underdogs with the Over (38.5) hitting. QB Nate Sudfeld went 14 of 27 for 196 yards with a TD and a pick, while QB Hendon Hooker went 12 of 15 for 150 yards.

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Steelers at Lions odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:39 a.m. ET.

  • Moneyline (ML): Steelers -300 (bet $300 to win $100) | Lions +240 (bet $100 to win $240)
  • Against the spread (ATS): Steelers -6.5 (-115) | Lions +6.5 (-105)
  • Over/Under (O/U): 35.5 (O: -110 | U: -110)

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Steelers at Lions picks and predictions

Prediction

Steelers 18, Lions 14

Moneyline

PASS.

There is no value on the Steelers (-300) as they will cost 3 times the potential return. If you believe the Lions will win (+240), the plus-money definitely has value, but I expect Detroit will take it easy on the road in this preseason finale.

Against the spread

BET LIONS +6.5 (-105).

Detroit won’t take it that easy, however. While the Steelers should perform better with Fields and Wilson captaining the offense, the Lions have proved their ability to not only stick in a game, but to come out on top. Expect Hooker and Sudfeld to keep Detroit within striking distance.

Over/Under

BET UNDER 35.5 (-110).

The Steelers have struggled to put points on the board in the preseason averaging an measly 7.5 points per game, while the defense has performed well, holding the Bills under 10 points last week.

The Lions allowed 14 points in their first game and scored just 3 in a loss at the Giants.

In what should be a hard-fought game, UNDER 33.5 (-110) is a solid wager.

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Detroit Lions at Kansas City Chiefs odds, picks and predictions

Analyzing Saturday’s Detroit Lions at Kansas City Chiefs odds and lines, with expert NFL picks and predictions.

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The Detroit Lions and Kansas City Chiefs meet Saturday in a Week 2 preseason matchup. Kickoff from GEHA Field at Arrowhead Stadium is set for 4 p.m. ET (NFL Network). Below, we analyze BetMGM Sportsbook’s lines around the Lions vs. Chiefs odds, and make our expert NFL picks and predictions.

Detroit lost 14-3 to the New York Giants on Aug. 8 in a game where no notable players suited up for Detroit. The Lions scored a 1st-quarter field goal before allowing the Giants to put up 2 TDs in the 2nd and neither team scored from that point on.

Kansas City lost 26-13 vs. the Jacksonville Jaguars last Saturday. KC’s starters played just 1 drive in the loss while Jacksonville’s starting unit played 2 drives.

Lions at Chiefs odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 3:59 p.m. ET.

  • Moneyline (ML): Lions +240 (bet $100 to win $240) | Chiefs -300 (bet $300 to win $100)
  • Against the spread (ATS): Lions +7 (-105) | Chiefs -7 (-115)
  • Over/Under (O/U): 39 (O: -110 | U: -110)

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Lions at Chiefs picks and predictions

Prediction

Chiefs 27, Lions 17

Moneyline

PASS.

The Chiefs should be able to pick up this win with some ease to cover as -300 favorites, but the line is set far too heavily to risk betting on. Bet on the spread and/or total instead.

Against the spread

BET CHIEFS -7 (-115).

With Kansas City planning to play its starters for the 1st half, the Chiefs will be able to jump out to a sizable lead that the backups can hold. KC is very good on both sides of the ball, so expect the starting offense to be able to score at will while the starting defense will shut down Detroit’s backups.

Over/Under

LEAN OVER 39 (-110).

Kansas City’s starting offense should be able to torch this Detroit 2nd unit in the 1st half to make it easy for the backups to finish the job and have this game hit the Over.

This is a lean because Kansas City’s 1st unit is great defensively which will make it hard for the Lions, who struggled to score against the Giants, to score in the 1st half.

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Las Vegas Raiders at Detroit Lions odds, picks and predictions

Analyzing Monday’s Las Vegas Raiders at Detroit Lions odds and lines, with expert NFL picks and predictions.

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The Las Vegas Raiders (3-4) and the Detroit Lions (5-2) wrap up the Week 8 slate on Monday Night Football. Kickoff from Ford Field is scheduled for 8:15 p.m. ET (ABC/ESPN). Below, we analyze FanDuel Sportsbook’s lines around the Raiders vs. Lions odds, and make our expert NFL picks and predictions.

Both teams are coming off ugly road losses where they didn’t score a TD until the 4th quarter when their respective games were out of hand.

Las Vegas lost as a 2.5-point favorite at the Chicago Bears 30-12. QB Brian Hoyer, starting in place of an injured Jimmy Garoppolo, only threw for 129 yards with 2 picks. He was replaced in the 4th quarter by rookie Aidan O’Connell, who was 10 of 13 with a TD and a pick in garbage time.

The setback snapped a short 2-game Raiders win streak — home victories vs. the New England Patriots (21-17 in Week 6) and the Green Bay Packers (17-13 in Week 5).

Detroit was spanked 38-6 as a 3-point underdog at the Baltimore Ravens. The Lions were outgained 503 to 337 yards and had no answer for Ravens QB Lamar Jackson, who threw for 3 TDs and ran for one as Baltimore built a 35-0 lead by the midpoint of the 3rd quarter.

The loss snapped a 4-game win and cover streak for the Lions.

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Raiders at Lions odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:56 a.m. ET.

  • Moneyline (ML): Raiders +275 (bet $100 to win $275) | Lions -340 (bet $340 to win $100)
  • Against the spread (ATS): Raiders +7.5 (-112) | Lions -7.5 (-108)
  • Over/Under (O/U): 46.5 (O: -115 | U: -105)

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Raiders at Lions key injuries

Raiders

  • K Daniel Carlson (groin) questionable
  • LB Divine Deablo (ankle) out
  • CB Nate Hobbs (ankle) questionable

Lions

  • OL Jonah Jackson (ankle) out
  • DL Benito Jones (ankle) questionable
  • RB David Montgomery (ribs) out
  • C Frank Ragnow (toe/calf) doubtful
  • WR Amon-Ra St. Brown (illness) questionable
  • OL Halapoulivaati Vaitai (back) questionable

Raiders at Lions picks and predictions

Prediction

Lions 35, Raiders 10

Moneyline

The Lions (-340) are a much better team than the Raiders, but risking 3.4 times the potential return is just not smart sports gambling. PASS.

Against the spread

DETROIT -7.5 (-108) is the STRONGEST PLAY – 1½ times your usual wager.

While playing at the Ravens last week wasn’t going to be an easy task, no one expected the Lions to get blown out the way the did.

Coach Dan Campbell and his players have to be chomping at the bit to get back at it and put last week’s debacle behind them. Las Vegas might be the perfect remedy to do so.

The Raiders don’t travel well. They are 1-3 on the road this season with a 1-2-1 ATS mark. Last season, they were 2-7 on the road with a 3-6 ATS record.

The Lions are known for covering the spread at home. While they’re only 2-1 ATS at home this season (and 2-1 straight up), they’re 9-3 ATS at Ford Field over the last 2 seasons and 15-5 ATS there since the start of the 2021 season.

The Raiders rank last in rushing at 68.6 yards per game. They haven’t had a 100-yard rushing game this season and they only could muster 39 rushing yards against the Bears last week.

The Lions feature the 2nd-best defense against the run, yielding 76.3 YPG — the Philadelphia Eagles are 1st at 65.5 YPG.

This should get ugly. Expect a blowout by the LIONS -7.5 (-108).

Over/Under

BET UNDER 46.5 (-105) TO WIN A HALF UNIT.

There’s something about Monday night games and Unders this season. The Under is 8-1 in Monday night games, including 6-0 in the last 6. Only the Week 2 Pittsburgh Steelers’ 26-22 home win vs. the Cleveland Browns cashed an Over (39.5) ticket.

Detroit is 4-3 O/U. The reason for the HALF UNIT is because the Lions averaged 31.0 points in their last 3 games. They will put up 30-plus points in this one, but will the Raiders score enough to hit this Over?

Las Vegas is averaging 16.0 points per game, ranking 30th in the league. The Under is 2-5 in the Raiders’ 7 games — they cashed 4 Unders in a row before the Over (38.5) hit in the Chicago loss.

Until the MNF Under trend ends, I’m going to keep riding it.

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Detroit Lions at Baltimore Ravens odds, picks and predictions

Analyzing Sunday’s Detroit Lions at Baltimore Ravens odds and lines, with expert NFL picks and predictions.

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The Detroit Lions (5-1) visit the Baltimore Ravens (4-2) Sunday. Kickoff from M&T Bank Stadium is at 1 p.m. ET (FOX). Below, we analyze FanDuel Sportsbook’s lines around the Lions vs. Ravens odds, and make our expert NFL picks and predictions.

The Detroit Lions play their second road game in a row after defeating the Tampa Bay Buccaneers 20-6 as 3-point favorites last Sunday. QB Jared Goff, despite all the criticism, has the best ATS record of any QB in the NFL over the past 5 seasons, according to The Action Network, and he leads this Detroit side which could be playing the best of any team right now.

Baltimore is coming off a 24-16 win as 5.5-point favorites vs. the Tennessee Titans last Sunday in London. QB Lamar Jackson has seemingly taken a step forward in his passing. With Todd Monken entering as offensive coordinator, the rushing of Jackson has taken a backseat to the pass game, and with rookie WR Zay Flowers entering the fray as a reliable weapon alongside TE Mark Andrews, Jackson finally has a duo he can rely on to get the ball to.

Detroit has been solid all around on offense. Although rookie RB Jahmyr Gibbs is missing some time, RB David Montgomery has filled in and been able to rush for 385 yards and 6 TDs in 5 games. Gibbs will return this week — an important fact as Montgomery, who injured his ribs last Sunday, is out.

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Lions at Ravens odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 9:10 p.m. ET.

  • Moneyline (ML): Lions +126 (bet $100 to win $126) | Ravens -148 (bet $148 to win $100)
  • Against the spread (ATS): Lions +3 (-118) | Ravens -3 (-104)
  • Over/Under (O/U): 43.5 (O: -105 | U: -115)

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Lions at Ravens key injuries

Lions

  • CB Brian Branch (ankle) available
  • RB Jahmyr Gibbs (hamstring) available
  • TE Sam LaPorta (calf) available
  • RB David Montgomery (ribs) out
  • CB Emmanuel Moseley (knee) out

Ravens

  • LB Tyus Bowser (knee) out
  • RB J.K. Dobbins (Achillies) out
  • LB David Ojabo (ankle) out
  • FS Marcus Williams (hamstring) out

Lions at Ravens picks and predictions

Prediction

Lions 21, Ravens 17

Moneyline

BET LIONS (+126).

Although Detroit is playing its second road game in a row, Detroit is still the better team.

Jackson has not been good as a favorite in recent years, and the Lions offensive line will be able to hold up against the Ravens front 7.

This is expected to be the windiest game of the day games with winds hoovering around 15-20 mph. This will limit any air game and force both teams to run. With Jackson limiting his running in 2023 and Dobbins out for the season, Baltimore will find it difficult to run against a Detroit defense which is No. 1 in the NFL, allowing only 64.7 yards/game to opponents.

Detroit will be able to perform on offense against the Ravens defense, and as the underdog, the +126 offers better value than the +3 does at -118.

Against the spread

PASS in favor of taking the underdog Lions on the moneyline.

Over/Under

BET UNDER 43.5 (-115).

Unders have been king so far this season, going 10-2 in Week 6. This game has all the markings of another Under with the wind blowing and both teams therefore looking to run the ball as much as possible.

Gibbs returns this week, and he will lead the backfield for Detroit, according to coach Dan Campbell. He will be counted on for the running game as well as in the screen game, and this will allow Detroit to move the ball and keep Baltimore and Jackson on the sidelines.

When Baltimore does get on the field, it will also look to rush the ball with RB Gus Edwards and RB Justice Hill. While they will try, going against the No. 1 rush defense in the NFL will not make it easy. This total (43.5) is low for a Lions game, with their offense. But they are coming in after a 20-6 win in Tampa Bay, and the wind here will make all the difference. TAKE THE UNDER 43.5 (-115), or stay away from a bet on the total.

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Detroit Lions at Tampa Bay Buccaneers odds, picks and predictions

Analyzing Sunday’s Detroit Lions at Tampa Bay Buccaneers odds and lines, with expert NFL picks and predictions.

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The Detroit Lions (4-1) will go up against the Tampa Bay Buccaneers (3-1) in Week 6 Sunday at Raymond James Stadium. Kickoff is scheduled for 4:25 p.m. ET (FOX). Below, we analyze BetMGM Sportsbook’s lines around the Lions vs. Buccaneers odds, and make our expert NFL picks and predictions.

The Lions improved to 4-1 on the season with a 42-24 win over the Carolina Panthers in Week 5, covering as 10-point home favorites and clearing the Over of 43.5. Detroit is on a 3-game winning streak and has its sights on its first playoff berth since the 2016 season.

The Buccaneers are coming off of their bye week following a 26-9 road victory as 4.5-point underdogs against the New Orleans Saints in Week 4. The Under of 41.5 hit in the win over New Orleans, and Tampa Bay is in 1st place in the NFC South.

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Lions at Buccaneers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 11:40 a.m. ET.

  • Moneyline (ML): Lions -165 (bet $165 to win $100) | Buccaneers +140 (bet $100 to win $140)
  • Against the spread (ATS): Lions  -3 (-110) | Buccaneers +3 (-110)
  • Over/Under (O/U): 42.5 (O: -110 | U: -110)

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Lions at Buccaneers key injuries

Lions

  • CB Brian Branch (ankle) out
  • RB Jahmyr Gibbs (hamstring) out
  • G Jonah Jackson (ankle) out
  • RB Zonovan Knight (shoulder) out
  • TE Sam LaPorta (calf) questionable
  • DE Joshua Paschal (knee) out

Buccaneers

  • LB Shaquil Barrett (illness) questionable

Lions at Buccaneers picks and predictions

Prediction

Lions 27, Buccaneers 20

Moneyline

While I believe the Lions will secure the win on the road Sunday, I’ll PASS on their moneyline in this contest. Taking a team at -165 odds straight up isn’t worth the risk.

Against the spread

LIONS -3 (-110) is the ideal choice in this matchup with Detroit forming into one of the most well-rounded teams in the league. The Lions are expected to get WR Amon-Ra St. Brown back on offense, while the Buccaneers could be without Evans.

Detroit is a perfect 2-0 ATS on the road this season and has won both of its road games thus far.

Over/Under

OVER 42.5 (-110) is the play in this showdown as the Lions have proven to be one of the best offenses in the NFL. The Lions are registering 29.6 points per game (4th-most in the NFL) and the Buccaneers are producing a solid 21 points per game this season.

Detroit is 3-1 to the Over in its last 4 games overall.

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Carolina Panthers at Detroit Lions odds, picks and predictions

Analyzing Sunday’s Carolina Panthers at Detroit Lions Week 5 odds and lines, with expert NFL picks and predictions.

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The Carolina Panthers (0-4) and the Detroit Lions (3-1) meet for a Week 5 matchup Sunday at Ford Field in Detroit. Kickoff is scheduled for 1 p.m. ET (FOX). Below, we analyze FanDuel Sportsbook’s lines around the Panthers vs. Lions odds, and make our expert NFL picks and predictions.

The Panthers suffered a 21-13 setback against the Minnesota Vikings in Week 4, failing to cover a 4-point number. Things got off to a good start, as S Sam Franklin had a 99-yard pick-6 to give Carolina the early lead. However, after leading 13-7 at halftime, the Panthers were outscored 14-0 in the 2nd half, with DL D.J. Wonnum posting a 51-yard scoop and score to turn the tide.

The Lions posted a 34-20 victory at Lambeau Field against the Green Bay Packers last Thursday, so Detroit has had 2 additional days to rest and prepare for the winless Panthers. Overall, the Lions are 3-1 against the spread (ATS), and Detroit hasn’t lost in regulation this season.

These teams met last season on Christmas Eve, with the Panthers posting a 37-23 win as a 2.5-point underdog. In fact, the underdog is a perfect 4-0 SU/ATS in the past 4 meetings in this series.

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Panthers at Lions odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 4:38 a.m. ET.

  • Moneyline (ML): Panthers +385 (bet $100 to win $385) | Lions -500 (bet $500 to win $100)
  • Against the spread (ATS): Panthers +9.5 (-112) | Lions -9.5 (-108)
  • Over/Under (O/U): 43.5 (O: -115 | U: -105)

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Panthers at Lions key injuries

Panthers

  • OG Austin Corbett (knee) out
  • CB Donte Jackson (shoulder) questionable
  • TE Stephen Sullivan (hip) out
  • FS Xavier Woods (hamstring) out

Lions

  • CB Brian Branch (ankle) out
  • FB Jason Cabinda (knee) out
  • OT Taylor Decker (ankle) questionable
  • RB Jahmyr Gibbs (hamstring) questionable
  • FS Kerby Joseph (hip) questionable
  • TE James Mitchell (hamstring) doubtful
  • DB Emmanuel Moseley (hamstring, knee) questionable
  • LB Julian Okwara (shoulder) questionable
  • WR Amon-Ra St. Brown (abdomen) doubtful
  • WR Josh Reynolds (groin) questionable
  • OG Halapoulivaati Vaitai (knee) questionable
  • WR Jameson Williams (not injury related) questionable

Panthers at Lions picks and predictions

Prediction

Lions 31, Panthers 16

Moneyline

Detroit (-500) will cost you 5 times your potential return. While Carolina (+385) has seldomly resembled an NFL-caliber team in the first 4 weekends of the season, that’s still way too much risk for not enough reward backing the Lions at this exorbitant of a price.

PASS, and look to the spread instead.

Against the spread

DETROIT -9.5 (-110) is a strong play at home, even with a rather lengthy injury report, and the likely event St. Brown, the team’s best receiver, will be sidelined. While double-digit favorites are risky business in the NFL, it’s unlikely Carolina +9.5 (-110) offers much resistance in this feline battle in the Motor City even against a shorthanded Lions side.

The Lions are a solid 3-1 ATS in 4 games overall, while averaging 25.5 points per game (PPG) in 2 home outings. The Panthers have scored 17 or fewer points in 3 of their 4 games, and the only time it exceeded that mark was when backup QB Andy Dalton filled in for an injured QB Bryce Young in Week 3 in Seattle.

Over/Under

OVER 43.5 (-115) is the lean, but go very lightly.

The Panthers have cashed the Under in 3 of 4 games, but the defense has yielded 20 or more points in each outing this season. The Lions should continue to add to their woes.

The Lions have scored 31 or more points in 2 of the past 3 games, cashing the Over in each of those outings. Detroit should roll up some solid yardage and point totals against the hapless Carolina side.

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Detroit Lions at Green Bay Packers odds, picks and predictions

Analyzing Thursday’s Detroit Lions at Green Bay Packers Week 4 odds and lines, with expert NFL picks and predictions.

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The Detroit Lions (2-1) and the Green Bay Packers (2-1) meet on Thursday Night Football in Week 4 at Lambeau Field. Kickoff is scheduled for 8:15 p.m. ET (Prime Video). Below, we analyze FanDuel Sportsbook’s lines around the Lions vs. Packers odds, and make our expert NFL picks and predictions.

The Lions play on the road on a Thursday night for the 2nd time in 4 games this season. Detroit opened the season with a 21-20 upset win against the Kansas City Chiefs, its 2nd straight regular-season primetime victory dating back to Week 18 last season. The Lions haven’t won 3 straight games under the lights since 1998.

The Packers and QB Jordan Love rallied for an 18-17 victory despite entering the 4th quarter down 17-0, covering for the 3rd time in as many outings. The Under result in Week 3 was the team’s first of the season. Green Bay lost to Detroit in Week 18 at home last season in primetime, and it is just 1-4 in the past 5 games under the lights.

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Lions at Packers odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Wednesday at 7:15 a.m. ET.

  • Moneyline (ML): Lions -124 (bet $124 to win $100) | Packers +106 (bet $100 to win $106)
  • Against the spread (ATS): Lions -1.5 (-110) | Packers +1.5 (-110)
  • Over/Under (O/U): 45.5 (O: -115 | U: -105)

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Lions at Packers key injuries

Lions

  • FB Jason Cabinda (knee) questionable
  • RB David Montgomery (thigh) questionable
  • CB Emmanuel Moseley (hamstring, knee) questionable
  • OL Halapoulivaati Vaitai (knee) questionable

Packersa

  • CB Jaire Alexander (back) questionable
  • OL David Bakhtiari (knee) questionable
  • LB De’Vondre Campbell (ankle) questionable
  • LB Rashan Gary (knee) questionable
  • OL Elgton Jenkins (knee) questionable
  • RB Aaron Jones (hamstring) questionable
  • WR Christian Watson (hamstring) questionable

Lions at Packers picks and predictions

Prediction

Lions 25, Packers 20

Moneyline

The LIONS (-124) are worth a roll of the dice to go 2-for-2 on Thursday night. Detroit enters the game in a lot of better shape from a health perspective.

The Packers have struggled on offense with Jones missing the past 2 games, and Watson sitting for all 3 games so far. Love showed a lot of poise, grit and determination leading a comeback last week, but the Lions are quite a bit more talented than the New Orleans team that Green Bay barely squeaked by.

Against the spread

The LIONS -1.5 (-110) are a little bit cheaper ATS than the moneyline, and therefore the better play is laying the small number of points — unless you feel the Lions are only going to win by a single point, or you think the game will end in a tie.

Over/Under

UNDER 45.5 (-110) is the lean, but go very, very lightly.

The Under cashed in both meetings between these NFC North rivals last season, with the Lions averaging 17.5 points per game (PPG) and allowing just 12.5 PPG in 2 Detroit wins. The Under is 6-3 in the past 9 meetings overall, with a slight 3-2 Under advantage in the past 5 battles at Lambeau.

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