First look: Detroit Lions at Indianapolis Colts odds and lines

Looking at Sunday’s Detroit Lions at Indianapolis Colts Week 12 NFL odds, lines and trends. Here’s what you need to know.

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The Detroit Lions (9-1) are on the road in Week 12 to take on the Indianapolis Colts (5-6). Kickoff Sunday from Lucas Oil Stadium is at 1 p.m. ET (FOX). Below, we look at Lions vs. Colts odds from BetMGM Sportsbook’s NFL odds before making our expert NFL picks and predictions later in the week.

The Lions have won 8 straight games and are coming off a 52-6 blowout win at home over the Jacksonville Jaguars. They easily covered the 14-point spread as favorites and covered the Over (47.5) themselves. After throwing 5 INTs in win over the Houston Texans, Lions QB Jared Goff passed for 412 yards and 4 TDs with only 5 incompletions.

The Colts snapped a 3-game losing streak on Sunday with a 28-27 road win over the New York Jets as 4-point underdogs while the Over (43.5) cashed. Colts QB Anthony Richardson returned to the starting lineup after a benching to pass for 272 yards and a TD and to rush for 2 other scores. His second TD run came with 46 seconds left in the game, giving the Colts the win.

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Lions at Colts odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Monday at 6:52 a.m. ET.

  • Moneyline (ML): Lions -375 (bet $375 to win $100) | Colts +300 (bet $100 to win $300)
  • Against the spread (ATS): Lions -8 (-110) | Colts +8 (-110)
  • Over/Under (O/U): 50.5 (O: -110 | U: -110)

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2024 betting stats

  • ML: Lions 9-1 | Colts 5-6
  • ATS: Lions 8-2 | Colts 8-3
  • O/U: Lions 5-4-1 | Colts 5-6

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Lions vs. Colts head-to-head

The Lions and Colts have faced each other 44 times since 1950 with the Colts ahead 22-20-2.

The Colts have won 5 of 6 meetings since 2000. Their last meeting was in 2020, a 41-21 Colts win in Detroit. The Lions’ last win over the Colts was in 2016, a 39-35 win in Indy.

This will be Richardson’s first career appearance against Detroit.

Goff is 1-0 against the Colts. That start came in Week 1 in 2017 when he played for the LA Rams. He was 21-for-29 passing for 306 yards and a TD in a 46-9 Rams win.

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