Dallas Cowboys at Los Angeles Rams odds, picks and best bets

Previewing the Dallas Cowboys at Los Angeles Rams Week 1 betting odds and lines, with NFL betting picks, tips and best bets.

The Dallas Cowboys will not only open the 2020 NFL season against the Los Angeles Rams Sunday night, but they’ll be the first road team to take the field at SoFi Stadium in Inglewood, Calif. Kickoff between these two Super Bowl hopefuls in the NFC is at 8:20 p.m. ET.

Cowboys at Rams betting odds and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 3:45 p.m. ET.

  • Moneyline: Cowboys -150 (bet $150, win $100) | Rams +125 (bet $100, win $125)
  • Against the Spread/ATS: Cowboys -2.5 (-110) | Rams +2.5 (-110)
  • Over/Under: 51.5 (O: -110, U: -110)

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Cowboys at Rams game notes

  • The last time these teams met, the Cowboys blew out the Rams 44-21 at home. The Rams won the previous two meetings, including a 30-22 victory in the playoffs two seasons ago.
  • The Rams are undefeated in Week 1 under head coach Sean McVay the last three seasons.
  • Dallas has an entirely new coaching staff on its sideline, led by head coach Mike McCarthy and defensive coordinator Mike Nolan.
  • The total has gone Over the projected number in six of the Cowboys’ last seven games against NFC opponents.
  • In their last 16 games against the NFC, the Rams are 12-3-1 against the spread.

Cowboys at Rams key injuries

Cowboys

  • CB Jourdan Lewis (ankle) out

Cowboys at Rams: Odds, betting lines, picks and prediction

Prediction

Cowboys 30, Rams 27

Moneyline (?)

The Rams won’t have home-field advantage this weekend with no fans allowed in SoFi Stadium, making it easier to see why Dallas is favored in this game. On paper, the Cowboys look like the better team, especially after a great offseason.

The Rams lost a ton of talent this spring and have a first-year coordinator leading the defense, which could spell trouble. Take the COWBOYS (-150) to win outright.

Against the Spread (?)

The Cowboys come in as 2.5-point favorites, which is where the line has remained for weeks. Dallas blew out the Rams at home last season behind a dominant offensive showing, and while the score isn’t likely to be as lopsided again, I do like the Cowboys in this one.

Take the COWBOYS -2.5 (-110) to win by a field goal and cover the spread Sunday night in what will be a back-and-forth contest.

Over/Under (?)

The Over/Under of 51.5 is the highest of any game left this week, and by a comfortable margin. Each team boasts stars on both sides of the ball, but there could be some coverage mix-ups and missed tackles on defense after the cancelation of the preseason.

I’m inclined to take the OVER 51.5 (-110) in this game, which could turn into a shootout between QBs Jared Goff and Dak Prescott.

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