First look: Indianapolis Colts at Tennessee Titans odds and lines

Looking at Sunday’s Indianapolis Colts at Tennessee Titans Week 6 NFL odds, lines and trends. Here’s what you need to know.

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The Indianapolis Colts (2-3) visit the Tennessee Titans (1-3) on Sunday. Kick from Nissan Stadium is scheduled for 1 p.m. ET (CBS). Below, we look at Colts vs. Titans odds from BetMGM Sportsbook’s NFL odds before making our expert NFL picks and predictions later in the week.

The Colts had a 2-game winning streak snapped on Sunday with a 37-34 loss against the Jacksonville Jaguars while covering as a 3.5-point road underdog. QB Joe Flacco went 33-of-44 for 359 yards and 3 TDs with WR Alec Pierce hauling in 3 receptions for 134 yards and a TD.

The Titans will be coming off of a bye-week after winning their 1st game of the season 31-12 over the Miami Dolphins while covering as a 2.5-point road underdog in Week 4.

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Colts at Titans odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Monday at 11:31 a.m. ET.

  • Moneyline (ML): Colts -115 (bet $115 to win $100) | Titans -105 (bet $105 to win $100)
  • Against the spread (ATS): Colts -1 (-110) | Titans +1 (-110)
  • Over/Under (O/U): 42.5 (O: -110 | U: -110)

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2024 betting stats

  • ML: Colts 2-3 | Titans 1-3
  • ATS: Colts 4-1 | Titans 1-3
  • O/U: Colts 3-2 | Titans 2-1-1

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Colts vs. Titans head-to-head

The Colts and Titans have squared off 58 times with the Colts ahead 37-21.

The Titans are 6-4 against the Colts in their last 10 matchups since 2019. The teams met in December of 2023 with the Colts winning 31-28 in overtime and covering as 1-point road favorites with the Over of 42 easily hitting.

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