First look: Indianapolis Colts at Jacksonville Jaguars odds and lines

Looking at Sunday’s Indianapolis Colts at Jacksonville Jaguars Week 5 NFL odds, lines and trends. Here’s what you need to know.

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The Indianapolis Colts (2-2) visit the Jacksonville Jaguars (0-4) in a Week 5 AFC South contest Sunday. The opening kickoff at EverBank Stadium will be at 1 p.m. ET (CBS) Let’s analyze BetMGM Sportsbook’s NFL odds around the Colts vs. Jaguars odds, and make our expert NFL picks and predictions.

Indianapolis grabbed a big early lead and then hung on for a 27-24 win over the Pittsburgh Steelers Sunday. The Colts were outgained, but leveraged the win — their 2nd in a row — on a plus-2 in turnovers and 8-of-15 performance in converting 3rd downs.

Jacksonville remained winless with a 24-20 loss to the Houston Texans Sunday. Host Houston scored the go-ahead TD with 18 seconds remaining in the 4th quarter. The Jaguars were outgained 445 yards to 313 in losing for the 9th time in their last 10 games.

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Colts at Jaguars odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Monday at 12:38 a.m. ET.

  • Moneyline: Colts +120 (bet $100 to win $120) | Jaguars -145 (bet $145 to win $100)
  • Against the spread (ATS): Colts +2.5 (+100) | Jaguars -2.5 (-120)
  • Over/Under (O/U): 46.5 (O: -110 | U: -110)

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2024 betting stats

  • ML: Colts 2-2 | Jaguars 0-4
  • ATS: Colts 3-1 | Jaguars 2-2
  • O/U: Colts 2-2 | Jaguars 1-3

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Colts vs. Jaguars head-to-head

The last 5 series meetings have seen Jacksonville go 4-1, but Indianapolis leads the all-time series 27-19 since the 2 sides 1st met in 1995.

In Jacksonville, the Jags have won 9 in a row; 6 of those have been by multiple scores (9 points or more).

Since 2019, the Jaguars are 8-2 straight up and 6-4 ATS. The Over has cashed in 3 straight meetings and is 6-4 across those last 10 contests.

At home, Jacksonville is 9-0 SU and 9-0 ATS since 2015.

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First look: Indianapolis Colts at Jacksonville Jaguars odds and lines

Looking at Sunday’s Indianapolis Colts at Jacksonville Jaguars Week 6 NFL odds, lines and trends. Here’s what you need to know.

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The Indianapolis Colts (3-2) square off against the Jacksonville Jaguars (3-2) in Week 6 on Sunday at EverBank Stadium. Kickoff is scheduled for 1 p.m. ET (CBS). Below, we look at Colts vs. Jaguars odds from BetMGM Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

The Colts covered as 2.5-point underdogs and the Under (43) hit in their 23-16 home win over the Tennessee Titans in Week 5. Indianapolis has won 3 of its last 4 games. Rookie QB Anthony Richardson is expected to miss time with a shoulder injury he suffered against Tennessee.

The Jaguars defeated the Buffalo Bills 25-20 in London in Week 5, winning outright as 5.5-point underdogs while the Under (48.5) cashed. Jacksonville played in London in back-to-back weeks, winning both games straight up and against the spread.

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Colts at Jaguars odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 9:14 a.m. ET.

  • Moneyline (ML): Colts +180 (bet $100 to win $180) | Jaguars -225 (bet $225 to win $100)
  • Against the spread (ATS): Colts +4.5 (-110) | Jaguars -4.5 (-110)
  • Over/Under (O/U): 45.5 (O: -110 | U: -110)

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2023 betting stats

  • ML: Colts 3-2 | Jaguars 3-2
  • ATS: Colts 3-2 | Jaguars 3-2
  • O/U: Colts 3-2 | Jaguars 2-3

Colts vs. Jaguars head-to-head

Sunday’s AFC South bout will mark the 46th all-time meeting between Indianapolis and Jacksonville. The Colts own a 27-18 record against the Jaguars.

The Jaguars have won 3 of the last 4 meetings, including a 31-21 win over the Colts in Week 1 of this season. The home team has won 16 of the last 18 meetings between Indianapolis and Jacksonville dating back to 2014.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Skyler Carlin on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

Access more NFL coverage:

TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CommandersWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWireTitansWire | VikingsWire | DraftWire | TouchdownWire | ListWire

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