Week 1 of the 2021 college football season kicks into full gear with a full slate of games Thursday, Sept. 2. Sportsbook Wire writers browsed the NCAAF odds and lines at Tipico Sportsbook and offer up their expert college football picks and predictions for Thursday’s biggest games.
Also see: 2022 CFP National Championship odds
Two teams from the top 25 of the AFCA Coaches Poll powered by USA TODAY Sports are in action Thursday, headline by No. 4 Ohio State taking on Weber State. The Citadel and No. 24 Coastal Carolina get Thursday’s slate underway with a 7 p.m. ET kickoff.
Odds provided by Tipico Sportsbook and last updated at 4:25 p.m. ET.
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