Cleveland Browns at Los Angeles Chargers odds, picks and prediction

Analyzing Sunday’s Cleveland Browns at Los Angeles Chargers odds and lines, with expert NFL picks, predictions and best bets.

The Cleveland Browns (3-1) travel to meet the Los Angeles Chargers (3-1) at SoFi Stadium Sunday. Kickoff is scheduled for 4:05 p.m. ET (CBS). Below, we look at the Browns vs. Chargers odds and lines, and make our best NFL picks, predictions and bets.

The Browns picked up a 14-7 road win against the Minnesota Vikings in Week 4. It has since been revealed QB Baker Mayfield is playing with a partially torn labrum in his non-throwing shoulder. Despite its signal-caller not at 100 percent Cleveland has won three straight and covered its last two.

The Chargers doubled up the Raiders 28-14 in an AFC West showdown Monday night at SoFi. It was the second straight win for the Bolts against a divisional foe as they topped the Kansas City Chiefs 30-24 on the road in Week 3. The Under is a perfect 4-for-4 for L.A.

Browns at Chargers odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 10:10 a.m. ET.

  • Money line: Browns +115 (bet $100 to win $115) | Chargers -140 (bet $140 to win $100)
  • Against the spread (ATS): Browns +2.5 (-107) | Chargers -2.5 (-115)
  • Over/Under (O/U): 47.5 (O: -108 | U: -112)

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Browns at Chargers key injuries

Browns

  • DE Jadeveon Clowney (elbow) questionable
  • DE Myles Garrett (ankle, knee) questionable
  • CB Troy Hill (toe) questionable
  • CB Greg Newsome II (calf) out
  • CB Denzel Ward (neck) questionable
  • LB Malcolm Smith (abdomen) questionable
  • TE David Njoku (knee) questionable
  • C JC Tretter (knee, back) questionable

Chargers

  • CB Chris Harris Jr. (shoulder) questionable
  • RB Justin Jackson (groin) doubtful

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Browns at Chargers odds, lines, predictions and picks

Prediction

Chargers 27, Browns 20

Money line

Play the CHARGERS (-140) on the money line in this marquee game. The biggest concern with playing the home side is it’s playing on a short week after an emotional win Monday. Also, the Browns are a tremendous running team, and L.A. ranks just 29th in the league with 139.5 rushing yards per game allowed.

If the Bolts can at least be somewhat effective against the run, they’ll be able to get it done.

Against the spread

The CHARGERS -2.5 (-115) is a strong play at home, especially if this line stays at or under a flat three. L.A. has an outstanding and balanced offense and a decent defense. Mayfield is nicked up, so the Browns may try to run the ball even more than they usually do.

Cleveland is also banged up in the back end of its defense, and that’s why L.A. is the play. Herbert should be able to take advantage of the absence of Newsome, while Hill and Ward are also dinged up and question marks.

Over/Under

The UNDER 47.5 (-115) is worth a small-unit play. The Under has cashed in all four games for the Chargers, and the Browns have hit the Under in each of their last two. Cleveland has allowed just 13 total points in its last two games.

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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First look: Cleveland Browns at Los Angeles Chargers odds and lines

Looking at Sunday’s Cleveland Browns at Los Angeles Chargers Week 5 NFL odds, lines and trends. Here’s what you need to know.

The Cleveland Browns (3-1) are riding a three-game win streak as they head west in Week 5 to visit the Los Angeles Chargers (3-1). Kickoff is set for 4:05 p.m. ET Sunday at SoFi Stadium. Below, we look at the Browns vs. Chargers odds and lines; check back for our NFL picks and predictions.

Since their opening-week loss at the Kansas City Chiefs, the Browns have reeled off wins over the Houston Texans (31-21), Chicago Bears (26-6) and Minnesota Vikings (14-7).

Cleveland has done so on the backs of the league’s top-ranked rushing attack (177.0 yards per game) – featuring RBs Nick Chubb (362 yards, 3 TD) and Kareem Hunt (234, 3 TD) – and a DE Myles Garrett-led defense which ranks in the top four in points (16.8) and yards (250.3) allowed per game and total sacks (14).

The Chargers, meanwhile, have notched two straight impressive AFC West victories, winning 30-24 on the road at Kansas City and knocking off the previously unbeaten Las Vegas Raiders 28-14 Monday. QB Justin Herbert (9 TD, 3 INT) and running back Austin Ekeler (424 yards from scrimmage, 4 total TD) lead a potent offense while the Bolts rank seventh with 18.5 points allowed per contest.

Browns at Chargers odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Tuesday at 8:51 a.m. ET.

  • Money line: Browns -110 (bet $110 to win $100) | Chargers -110 (bet $110 to win $100)
  • Against the spread (ATS): Browns +0.5, -110, (bet $110 to win $100) | Chargers -0.5, -110 (bet $110 to win $100)
  • Over/Under (O/U): 49.5, O: -110 (bet $110 to win $100) | U: -110 (bet $110 to win $100)

Also see: Betting 101

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2021 betting stats:

  • ML: Browns 3-1 | Chargers 3-1
  • ATS: Browns 3-1 | Chargers 3-1
  • O/U: Browns 2-2 | Chargers 0-4

WIN YOUR FANTASY FOOTBALL LEAGUE!

For 25 years, TheHuddle.com has been helping fantasy players just like you win. This year, it’s your turn! Custom player rankings, tools and more to give you the edge over your competition.

Use code SBW21 to take 20% OFF a new subscription. Join now!

Browns vs. Chargers head-to-head

Los Angeles holds a 17-9-1 lead in the all-time series, including an 8-4 record serving as a host in California.

The Chargers won seven of nine meetings straight up (3-6 ATS) since 2003 and rolled to a 38-14 win in 2018 when they last met, easily covering as one-point road underdogs.

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com. Please gamble responsibly.

Follow @kenpomp on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Access more NFL coverage:

TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWireTitansWire | VikingsWire | WashingtonFootballWire | DraftWire | TouchdownWire | TheListWire

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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