The season opens for the Clemson Tigers and the Wake Forest Demon Deacons Saturday at Truist Field in Winston-Salem, N.C., for a 7:30 p.m. ET kickoff. We analyze the Clemson-Wake Forest college football betting odds and lines, with picks and best bets.
The Tigers are ranked No. 1 in the Amway Coaches Poll powered by USA TODAY Sports.
Clemson at Wake Forest: Betting odds and lines
Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Friday at 1:50 a.m. ET.
- Moneyline: Clemson -10000 | Wake Forest +1600
- Against the spread/ATS: Clemson -33.5 (-110) | Wake Forest +33.5 (-110)
- Over/Under: 59.5 (O: -110 | U: -110)
Clemson at Wake Forest: Three things to know
- Wake Forest WR Sage Surratt elected to opt out for the 2020 season to prepare for the NFL Draft. His production will be missed, as he posted 66 receptions for 1,001 yards and 11 touchdowns in 2019.
- Clemson DE Xavier Thomas is expected to return at some point, but he will miss the opener as he recovers from COVID-19.
- The Tigers have posted a 10-1 ATS mark in their past 11 games as a road favorite, while going 11-2 ATS in their previous 13 overall. Meanwhile, Wake Forest is just 2-6 ATS in its past eight as a home underdog.
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Clemson at Wake Forest: Odds, betting lines and picks
Prediction
Clemson 45, Wake Forest 17
Moneyline (ML)
Clemson (-10000) is an overwhelming favorite, but even if you tossed the Tigers into a 10-game parlay, it’s not worth it. Straight up, a $10 bet on Clemson would net a profit of a $0.10. Yeah, AVOID.
Also see:
- CFN – The latest college football coverage
Against the spread (ATS)
WAKE FOREST +33.5 (-110) should be able to do enough to hang on for the cover on its home field despite the fact it will be without its biggest offensive weapon in Surratt. It might require a late score for the Deacs to cover in the second half, but they’ll keep it within five touchdowns.
Over/Under (O/U)
The OVER 59.5 (-110) is worth a look, as Clemson QB Trevor Lawrence will come out looking to make a statement in his first game. The Heisman Trophy favorite is risking a lot playing during this strange season, so look for him to make it worth his while. The Tigers are going to roll up plenty of points in the first three quarters before they call off the dogs.
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