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The Cincinnati Bearcats (5-4, 3-3 Big 12) meet the No. 25 Iowa State Cyclones (7-2, 4-2) at Jack Trice Stadium Saturday. Kickoff is at 8 p.m. ET (FOX). Below, we look at Cincinnati vs. Iowa State odds from BetMGM Sportsbook’s college football odds and make our expert college football picks and predictions.
Cincinnati’s skid extended to 2 games after a 31-24 loss to West Virginia, who covered as 5-point road underdogs. The Over 54.5 hit, despite the Bearcats outgaining the Mountaineers by 188 yards. Turnovers proved costly, with Cincinnati committing 3. RB Evan Pryor was a standout, hauling in 5 receptions for 100 yards, highlighted by an 80-yard touchdown.
No. 25 Iowa State dropped its 2nd straight game, falling 45-36 to Kansas as 2-point home underdogs. The Over 52.5 cashed as the Cyclones struggled to stop Kansas’ offense, which tallied 295 passing and 237 rushing yards. QB Rocco Becht threw for 383 yards and 3 touchdowns but had a critical interception. WR Jaylin Noel stood out, recording 8 catches for 167 yards and 2 touchdowns in the loss.
– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports
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Cincinnati vs. Iowa State odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of college football odds. Lines last updated at 11 a.m. ET.
- Moneyline (ML): Cincinnati +240 (bet $100 to win $240) | Iowa State -300 (bet $300 to win $100)
- Against the spread (ATS): Cincinnati +7.5 (-110) | Iowa State -7.5 (-110)
- Over/Under (O/U): 52.5 (O: -110 | U: -110)
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Cincinnati vs. Iowa State picks and predictions
Prediction
Iowa State 30, Cincinnati 21
Moneyline
PASS.
Iowa State (-300) takes this game at home Saturday, but instead of laying 3-to-1, I’ll take my bet to the spread.
Against the spread
BET IOWA STATE -7.5 (-110).
Both teams are desperate for a win to end their recent skids, but Iowa State is favored to rebound Saturday and continue its push to surpass last season’s 6-3 conference record. The Cyclones’ defense, led by Jon Heacock, allows just 18.8 points per game, ranking 2nd in the Big 12 and 19th nationally. Becht commands the offense, leading the conference in yards per attempt (8.6) and yards per completion (14.0), with a 16:7 TD-INT ratio. Noel (892 yards, 5 TDs) and WR Jayden Higgins (791 yards, 7 TDs) provide big-play threats. Iowa State is 5-4 ATS this year and handled Cincinnati 30-10 in their last meeting.
Over/Under
BET UNDER 52.5 (-110).
Iowa State and Cincinnati showcase solid defenses this season, with the Cyclones allowing 18.8 points per game (2nd in the Big 12) and the Bearcats giving up 22.2 (6th in the conference). Cincinnati has gone over in 3 of 9 games, including a 1-2-1 record on the road, while Iowa State sits at 5-4 on Overs. The Under looks like the smarter play.
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