Week 1 first look: Central Michigan Chippewas at Missouri Tigers odds and lines, Mizzou double-digit favorite

Previewing the college football Week 1 matchup between the Central Michigan Chippewas and Missouri Tigers, with odds, trends and head-to-head records.

The Central Michigan Chippewas and Missouri Tigers open their 2021 regular season Saturday at Faurot Field at Memorial Stadium. Kickoff is scheduled for 4 p.m. ET. Below, we look at the Central Michigan vs. Missouri odds and lines; check back for our college football picks and predictions.

The Chips of CMU won three and lost three last season, with two victories coming on the road. They were also a perfect 3-0 ATS away from Mount Pleasant, Mich., something bettors hope can continue into 2021.

Mizzou ended up going 5-5 and was expected to play in the Music City Bowl against Iowa. Unfortunately, a spike in positive COVID-19 cases within the program caused the bowl game to be canceled, ending the season prematurely.

Central Michigan at Missouri odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 8:10 p.m. ET.

  • Money line: Central Michigan +440 (bet $100 to win $440) | Missouri -650 (bet $650 to win $100)
  • Against the spread/ATS: Central Michigan +14.5, -117 (bet $117 to win $100) | Missouri -14.5, -103 (bet $103 to win $100)
  • Total (Over/Under): 60.5, O: -112 (bet $112 to win $100) | U: -108 (bet $108 to win $100)

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2020 betting stats:

  • ML: Central Michigan 3-3 | Missouri 5-5
  • ATS: Central Michigan 4-2 | Missouri 5-5
  • O/U: Central Michigan 3-3 | Missouri 5-5

Central Michigan at Missouri head-to-head

These two schools are meeting on the gridiron for the first time. CMU last played an SEC school Sept. 1, 2018, a 35-20 loss at Kentucky. Mizzou hasn’t played a MAC institution since Sept. 10, 2016, a 61-21 win over Eastern Michigan.

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