Carolina Panthers at New Orleans Saints odds, picks and predictions

Analyzing Sunday’s Carolina Panthers at New Orleans Saints odds and lines, with expert NFL picks and predictions.

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The Carolina Panthers and New Orleans Saints open their regular seasons at the Caesars Superdome Sunday. Kickoff is scheduled for 1 p.m. ET (FOX). Below, we analyze FanDuel Sportsbook’s lines around the Panthers vs. Saints odds, and make our expert NFL picks and predictions.

The Panthers have QB Bryce Young entering Year 2, and apparently he made strides in training camp. The team also surrounded him with more weapons, trading for WR Diontae Johnson, while getting back into the 1st round of the 2024 NFL Draft to select South Carolina WR Xavier Legette.

The Saints swept the season series in 2023 while going 1-0-1 against the spread (ATS) at most shops. New Orleans has won 4 of the past 5 games at home against Carolina, with a meaningless Week 18 game won by the Panthers Jan. 8, 2023, as the lone exception. The Under has cashed in 7 straight meetings in this series.

New Orleans has won and covered 3 in a row inside the NFC South, and the Under cashed in 5 of 6 divisional games last season.

Carolina also saw the total go 5-1 in the past 6 divisional contests while going 1-5 straight up (SU) and 2-3-1 ATS in those outings.

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Panthers at Saints odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:20 a.m. ET.

  • Moneyline (ML): Panthers +176 (bet $100 to win $176) | Saints -210 (bet $210 to win $100)
  • Against the spread: Panthers +3.5 (-104) | Saints -3.5 (-118)
  • Over/Under (O/U): 41.5 (O: -108 | U: -112)

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Panthers at Saints key injuries

Panthers

  • TE Tommy Tremble (hamstring, back) out

Saints

  • LB Willie Gay Jr. (back) questionable
  • DT Khalen Saunders (calf) out

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Panthers at Saints picks and predictions

Prediction

Saints 23, Panthers 16

Moneyline

The Saints (-210) will set you back more than 2 times your potential return if you want to back the home side straight up and not play around with the points. That’s a little too expensive for a standalone wager, but as part of a multi-leg parlay, especially in Week 1, when we’re being a little more conservative, it’s OK to toss in with a few other teams.

PASS.

Against the spread

The SAINTS -3.5 (-118) are worth a look laying the points, although that hook is always bothersome. When betting the favorite, it’s always more appealing taking the flat 3, rather than the 3 and a hook.

Still, New Orleans should be able to handle its business against the Panthers +3.5 (-104), who need to prove to bettors and NFL fans that they’re way better than the past 2 seasons before we start trusting them again.

Over/Under

UNDER 41.5 (-112) is a strong play in this NFC South battle.

  • Vegas’ Alex White agrees: “Lock it in” play of the day

The Under cashed in 5 of 6 divisional games for each of these teams last season and went 2-0 in their head-to-head meetings.

The most recent meeting in New Orleans saw the home side win 28-6 in Week 14 of the 2023 campaign. In fact, the total has gone low in 7 straight meetings since Jan. 3, 2021. Until we see big offense in this series again, keep going low.

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Lock it in with Alex: Cash in on this NFL Week 1 Under

SportsbookWire.com’s Alex White likes a total in Sunday’s NFL Week 1 between the Carolina Panthers and New Orleans Saints.

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Alex White of SportsbookWire.com found an Over/Under total “that is way too high.”

The Carolina Panthers visit the NFC South rival New Orleans Saints Sunday in Week 1. Kickoff from Caesars Superdome is set for 1 p.m. ET (FOX).

BetMGM Sportsbook has the Over/Under in Panthers-Saints at 41.5 (Over: -110 | Under: -110). Lines last updated Saturday at 5:27 p.m. ET.

Listen below to why Alex is backing this play.

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First look: Carolina Panthers at New Orleans Saints odds and lines

Looking at Sunday’s Carolina Panthers at New Orleans Saints Week 1 NFL odds, lines and trends. Here’s what you need to know.

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The Carolina Panthers and the New Orleans Saints open the NFL regular season Sunday at Caesars Superdome. Kickoff is scheduled for 1 p.m. ET (FOX). Below, we look at Panthers vs. Saints odds from BetMGM Sportsbook before making our expert NFL picks and predictions later in the week.

Hope springs eternal in Charlotte, as the Panthers look to put an ugly 2-15 season in the rear-view mirror. Carolina wrapped up the 2023 campaign with a pair of shutout losses, while scoring 10 or fewer points in 4 of the final 5 outings.

Carolina moved back into the 1st round of the 2024 NFL Draft to nab South Carolina WR Xavier Legette to help QB Bryce Young. And, the Panthers added WR Diontae Johnson from the Pittsburgh Steelers, as the team looks to inject a little excitement into new coach Dave Canales’ offense.

The Saints posted a 9-8 record last season, but just missed out on the postseason. New Orleans finished up strong with 4 wins in the final 5 regular-season games, while going 4-1 against the spread (ATS) to finish things out.

Carolina was a dismal 0-9 on the road last season, while going 1-11 against NFC teams, and 1-5 inside the division.

New Orleans went a respectable 5-3 at home in 2023, while posting a 4-8 mark against the NFC, and 3-3 inside the division.

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Panthers at Saints odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 12:14 a.m. ET.

  • Moneyline (ML): Panthers +175 (bet $100 to win $175) | Saints -210 (bet $210 to win $100)
  • Against the spread (ATS): Panthers +4.5 (-120) | Saints -4.5 (+100)
  • Over/Under (O/U): 41.5 (O: -110 | U: -110)

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2023 betting stats

  • ML: Panthers 2-15 | Saints 9-8
  • ATS: Panthers 4-11-2 | Saints 6-10-1
  • O/U: Panthers 5-11-1 | Saints 6-11

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Panthers vs. Saints head-to-head

These NFC South teams meet twice each regular season. The Saints swept the series in 2023, winning 20-17 in Week 2 on a Monday night, pushing as a 3-point favorite as the Under (39.5) cashed. In Week 14, New Orleans pounded Carolina 28-6 as a 5.5-point favorite as the Under (39) cashed again.

The Saints have won 7 of the past 10 meetings since Nov. 24, 2019, with Carolina holding a 5-4-1 ATS advantage in the span. The Under has cashed in 7 straight meetings in this series since Jan. 3, 2021.

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Carolina Panthers at New Orleans Saints odds, picks and predictions

Analyzing Sunday’s Carolina Panthers at New Orleans Saints odds and lines, with expert NFL picks, predictions and best bets.

The Carolina Panthers (6-10) finish their season against the New Orleans Saints (7-9) in the Caesars Superdome Sunday at 1 p.m. ET (FOX). Below, we analyze Tipico Sportsbook’s lines around the Panthers vs. Saints odds, and make our expert NFL picks and predictions.

The 2022 season was not kind to the Panthers and Saints. Both came in with postseason aspirations — or at the very least finishing better than .500 — but they find themselves out of the playoff picture when they take the field Sunday.

The NFC South rivals faced off in Week 3 with the Panthers, as 9.5-point home underdogs, upsetting the Saints 22-14. QB Baker Mayfield (now with the Rams) and RB Christian McCaffrey (now with 49ers) started for Carolina, while QB Jameis Winston (season-ending injury) and WR Michael Thomas (on injured reserve) started for New Orleans. They won’t be involved Sunday, so little can be taken from that 1st game to analyze this one.

Both teams are eliminated and will end with losing records. The Panthers controlled their destiny entering Week 17 but lost as 3.5-point road underdogs to Tampa Bay 30-24. The Saints surprisingly upset a Jalen Hurt-less Eagles 20-10 last week — New Orleans was a 5.5-point road dog.

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Panthers at Saints odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 3:14 a.m. ET.

  • Moneyline (ML): Panthers +155 (bet $100 to win $155) | Saints -180 (bet $180 to win $100)
  • Against the spread (ATS): Panthers +3.5 (-115) | Saints -3.5 (-105)
  • Over/Under (O/U): 41.5 (O: -111 | U: -109)

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Panthers at Saints key injuries

Panthers

  • DL Brian Burns (ankle) questionable
  • RB D’Onta Foreman (knee) questionable
  • DL Yetur Gross-Matos (hamstring) questionable
  • DL Matthew Ioannidis (back) questionable

Saints

  • CB Paulson Adebo (hamstring) out
  • TE Taysom Hill (back) questionable
  • OL James Hurst (foot) questionable
  • TE Juwan Johnson (quad) questionable
  • S Marcus Maye (shoulder) questionable
  • OL Andrus Peat (ankle) questionable
  • OL Ryan Ramczyk (hip) questionable

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Panthers at Saints picks and predictions

Prediction

Saints 17, Panthers 16

Moneyline

Despite their record, the Saints are pretty good against the pass. They are 3rd in passing yards allowed per game (193.9) and 4th in opponent yards per pass (6.0).

The run game is a different story. After the Panthers put up 320 rushing yards against the Lions in Week 16, they could harass a New Orleans team that’s 23rd in yards per rush (4.5). The moneyline odds should be AVOIDED but you may consider a rushing prop.

Against the spread

The Saints are 1-5 against the spread in their past 6 games when their defense holds opponents to 90 rushing yards or less in their previous game.

On top of that, the Panthers have covered in 7 of their last 8 games after hitting more than 350 total yards in their last game.

BET PANTHERS +3.5 (-115).

Over/Under

Both teams lean toward the Under. The Panthers hit the Under is 5 of their last 7 games after an ATS loss.

For the Saints, the Under is 5-0 in their last 5 games and they’ve posted 4 straight Unders following an ATS win.

LEAN UNDER 41.5 (-109).

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Carolina Panthers at New Orleans Saints odds, picks and prediction

Analyzing Sunday’s Carolina Panthers at New Orleans Saints Week 17 odds and lines, with expert NFL picks, predictions and best bets.

The Carolina Panthers (5-10) visit the New Orleans Saints (7-8) Sunday for a Week 17 tilt at Caesars Superdome. Kickoff is scheduled for 4:25 p.m. ET. Below, we look at the Panthers vs. Saints odds and lines, and make our best NFL picks, predictions and bets.

The Panthers have been horrible lately, hitting rock bottom in a 32-6 home loss against the Tampa Bay Buccaneers last week. The Panthers are 0-5 straight up and 0-5 against the spread in the past five games since a stunning 34-10 upset win at Arizona in Week 10.

Head coach Matt Rhule announced earlier this week that QB Sam Darnold will start, benching fan favorite QB Cam Newton.

The Saints were dropped 20-3 at home against the Miami Dolphins Monday night. Third-string QB Ian Book started, making is NFL debut, as starting QB Taysom Hill and backup Trevor Siemian were unavailable. Hill has since been activated from the COVID-19 list, so the book is closed on the Notre Dame rookie quarterback for now.

Also see: All Week 17 odds and lines

Panthers at Saints odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 7:55 a.m. ET.

  • Money line: Panthers +230 (bet $100 to win $230) | Saints -300 (bet $300 to win $100)
  • Against the spread (ATS): Panthers +6.5 (-110) | Saints -6.5 (-110)
  • Over/Under (O/U): 37.5 (O: -112 | U: -108)

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Panthers at Saints key injuries

Panthers

  • DE Brian Burns (reserve/COVID-19 list) questionable
  • S Juston Burris (groin) questionable
  • LB Jermaine Carter Jr. (groin) questionable
  • OT Cameron Erving (calf) questionable
  • CB Stephon Gilmore (groin) questionable
  • LB Haason Reddick (reserve/COVID-19 list) questionable
  • C Sam Tecklenburg (reserve/COVID-19 list) questionable
  • LB Shaq Thompson (reserve/COVID-19 list) questionable
  • WR Brandon Zylstra (reserve/COVID-19 list) questionable

Saints

  • OT Terron Armstead (knee) questionable
  • DE Marcus Davenport (shoulder) questionable
  • RB Mark Ingram II (knee) questionable
  • C Erik McCoy (reserve/COVID-19 list) questionable
  • WR Ty Montgomery (back) questionable
  • OT Ryan Ramczyk (reserve/COVID-19 list) questionable
  • WR Tre’Quan Smith (chest) questionable
  • TE Nick Vannett (ankle) questionable
  • S Marcus Williams (reserve/COVID-19 list) questionable

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Panthers at Saints odds, lines, predictions and picks

Prediction

Saints 20, Panthers 12

Money line

The Saints (-300) will cost you three times your potential return, but that’s risky business, even against the struggling Panthers.

PASS and look to the spread instead.

Against the spread

The SAINTS -6.5 (-110) are a better play laying the points. Carolina gives Darnold a start to see what he can do, and it likely won’t be much against a strong New Orleans defense.

The Saints have yielded just 22 offensive points across the past three outings. This play doesn’t come without risk, however, as the offense has managed just 12 total points in the previous two games.

Over/Under

The UNDER 37.5 (-108) is the play even though this line is super low. The Under has connected in five straight games for the Saints. The Under also hit in the first meeting between these NFC South rivals in Week 2, a 26-7 win by Carolina which seems like a lifetime ago.

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First look: Carolina Panthers at New Orleans Saints odds and lines

Looking at Sunday’s Carolina Panthers at New Orleans Saints Week 17 NFL odds, lines and trends. Here’s what you need to know.

The Carolina Panthers (5-10) visit the New Orleans Saints (7-8) for a Week 17 matchup Sunday. Kickoff from Caesars Superdome is scheduled for 4:25 p.m. ET. Below, we look at the Panthers vs. Saints odds and lines; check back for our NFL picks and predictions.

The Panthers were smashed 32-6 at home by the Tampa Bay Buccaneers as 11.5-point underdogs as the Under (43.5) connected. Carolina is 0-5 straight up and against the spread in its past five games since a Week 10 win at Arizona. The Over is 5-1 across the past six contests.

Also see: All Week 17 odds and lines

The Saints lost 20-3 to at home to the Miami Dolphins Monday night. New Orleans was forced to roll with third-string QB Ian Book for his first NFL start, as QBs Taysom Hill and Trevor Siemian were unavailable due to a COVID-19 outbreak among the team.

Panthers at Saints odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Tuesday at 2:16 a.m. ET.

  • Money line: Panthers +260 (bet $100 to win $260) | Saints -340 (bet $340 to win $100)
  • Against the spread (ATS): Panthers +6.5, -105 (bet $105 to win $100) | Washington -6.5, -115 (bet $115 to win $100)
  • Over/Under (O/U): 38.5, O: -105 (bet $105 to win $100) | U: -115 (bet $115 to win $100)

Also see: Betting 101

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2021 betting stats:

  • ML: Panthers 5-10 | Saints 7-8
  • ATS: Panthers 5-10 | Saints 7-8
  • O/U: Panthers 7-8 | Saints 6-9

Panthers at Saints head-to-head

These teams met in Week 2 in Charlotte with the Panthers coming away with a 26-7 win as 3-point underdogs as the Under (45) cashed.

New Orleans has won four of the past five meetings, although the Panthers are 6-2 ATS across the past eight meetings. The Over is 4-2 in the previous six, but the Under hit in the past two matchups.

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Underdog corner: 3 best NFL picks and predictions for Week 2

Assessing the NFL betting odds and lines for Week 2, with three predictions and picks for the best underdog bets to make.

NFL point-spread underdogs certainly had their day in Week 1 and a record one at that, covering in 12 of 16 games with an amazing nine outright winners. We took full advantage here in underdog corner as all three of our selections (the Philadelphia Eagles, Houston Texans and Miami Dolphins, who were all getting 3.5 points) notched straight-up wins, including two by double digits.

Certainly, a week to rejoice, but we know it’s not going to be that fruitful every week. We are wagering on the NFL (Not For Long) after all. Below, we assess the odds and matchups and offer up our three best NFL underdog picks and predictions for Week 2.

NFL underdog predictions: Week 2

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Wednesday at 6 p.m. ET.

Carolina Panthers +3.5 (-112) vs. New Orleans Saints, Sunday at 1 p.m. ET

The Saints surprised many by notching one of the most shocking wins of Week 1, routing reigning MVP QB Aaron Rodgers and the favored Green Bay Packers 38-3 in a neutral-site game in Jacksonville.

The win, though, came with a cost as three starters — CB Marshon Lattimore, DE Marcus Davenport and C Erik McCoy — went down and will miss time due to injuries.

Also, a mini-COVID-19 outbreak has since struck the organization with six assistant coaches among eight in all testing positive so far. In addition to the inconvenience of practicing and staying in the Dallas area after being displaced by Hurricane Ida, the Saints now will be operating under the league’s enhanced COVID mitigation protocols this week.

The Panthers, meanwhile, have no such distractions playing at home for the second straight week after opening with a 19-14 win over the New York Jets. Carolina also covered in five of its last seven games against the Saints as an underdog, and given all the above, we’ll say that grows to six of eight with an outright PANTHERS (+3.5, +155 ML) win Sunday.

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Minnesota Vikings +3.5 (-107) at Arizona Cardinals, Sunday at 4:05 p.m. ET

QB Kyler Murray and the Cards also pulled off a Week 1 stunner, routing the field goal-favorite Tennessee Titans 38-13 on the road.

The Vikings didn’t fare nearly as well in their season opener in Cincinnati, falling 27-24 on the last play of overtime.

We see things evening out, though, Sunday afternoon in the desert as these still look to be two equally-matched teams. Take the VIKINGS (+3.5).

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Dallas Cowboys +3.5 (-122) at Los Angeles Chargers, Sunday at 4:25 p.m. ET

This will be the Bolts’ home opener — and their first game at SoFi Stadium with fans; however, given the Chargers’ lack of serious L.A. backing, that only means the sparkling new stadium will mainly be filled with Cowboys fanatics.

On the field, second-year Chargers QB Justin Herbert certainly looks to be the real deal but QB Dak Prescott and the Cowboys should’ve beaten the defending-champion Tampa Bay Buccaneers, losing 31-29 late in the league’s season opener.

Dallas is still getting more than a field goal against a lesser foe, so get down on the COWBOYS (+3.5).

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