Carolina Panthers vs. Dallas Cowboys odds predictions pick betting line spread

The Carolina Panthers (3-0) and Dallas Cowboys (2-1) meet at AT&T Stadium in Arlington, Texas in Week 4. Kickoff is scheduled for 1 p.m. ET. Below, we look at the Panthers vs. Cowboys odds and lines, and make our best NFL picks, predictions and bets.

The Panthers have surprised with three victories through three outings, including a win last time they were in the state of Texas in Week 3. Carolina won 24-9 and covered as an 8-point favorite against the Houston Texans last week. The Panthers are 3-0 against the spread and the Under is also 3-0.

Carolina ranks first in total yards allowed per game (191.0), passing yards allowed (146.0) and rushing yards allowed (45.0). Its 10.0 PPG allowed ranks second in the NFL.

The Cowboys are also 3-0 ATS, going for 416.7 total yards per game to rank fifth in the NFL. The run game has been solid, too, averaging 139.3 yards per game to rank fourth. They’re also putting up 30.0 PPG, so they’ll easily be the biggest test for the Panthers so far.

Also see: NFL Week 4 staff picks

Panthers at Cowboys odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 9:30 a.m. ET.

Money line: Panthers +165 (bet $100 to win $165) | Cowboys -205 (bet $205 to win $100)
Against the spread (ATS): Panthers +4.5 (-115) | Cowboys -4.5 (-107)
Over/Under (O/U): 51.5 (O: -115 | U: -105)

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Panthers at Cowboys key injuries

Panthers

DE Yetur Gross-Matos (ankle) doubtful
RB Christian McCaffrey (hamstring) out
G John Miller (shoulder) questionable

Also see: On Site

Cowboys

DE Randy Gregory (knee) questionable
OT Ty Nsekhe (illness) out
DE Dorance Armstrong (ankle) out
DE Carlos Watkins (knee) out
S Donovan Wilson (groin) out

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Panthers at Cowboys odds, lines, predictions and picks

Prediction

Cowboys 26, Panthers 17

Money line

The Cowboys (-205) will cost you more than two times your potential return, and that’s just too expensive against an undefeated team.

AVOID, and look to the spread instead.

Against the spread

The COWBOYS -4.5 (-107) are the play at home. Yes, the Panthers are unbeaten, but real only real quality victory was the win in Week 2 against the visiting New Orleans Saints. The New York Jets are winless, and the Houston Texans have just one win.

Toss in the fact the Panthers are missing their best player, McCaffrey, and it’s going to be the longest day at the office for Carolina to date.

Over/Under

UNDER 51.5 (-105) is the best play on the board. The Panthers have been tremendous defensively, while the Cowboys have also managed to keep the opposition down. This won’t be a defensive slog, but it also won’t be an offensive shootout with tons of fireworks.

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Our unblemished record fell by the wayside last Sunday as the New York Jets failed to cover the 10.5-point spread on the road against the Denver Broncos. (Deep analysis: Covering is almost always tougher when a team doesn’t score.) Below, we look at the top NFL underdog picks and predictions of Week 4.

Nevertheless, we hit on the New Orleans Saints and Los Angeles Chargers, who both won outright on the road, to improve to 8-1 against the spread on the season. Seven of our nine underdog picks so far have notched straight-up, wins as well.

Jump aboard for Week 4 to see if we can keep the train rolling.

Also see: All Week 4 odds and lines

NFL underdog predictions: Week 4

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Wednesday at 4:25 p.m. ET.

Carolina Panthers +4.5 (-115) at Dallas Cowboys

QB Dak Prescott and the Cowboys were certainly impressive in their 2021 Big D debut Monday night, smashing the rival Philadelphia Eagles 41-21 to improve to 2-1 straight up and 3-0 against the spread.

The Panthers will be without injured do-it-all running back Christian McCaffrey so why are we on Carolina here in this meeting of 3-0 ATS teams? Three reasons:

The Panthers have a distinct rest advantage having last played a week ago Thursday night.
The Carolina defense has been an underrated force so far, leading the league in sacks (14), total QB pressures (47) and rushing defense (45 yards allowed per game, 2.6 yards per carry).
It’s an obvious letdown spot for the Cowboys coming off an emotional, prime-time rout of a division rival.

Dallas likely still wins, but the Panthers keep it close and cover.

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Arizona Cardinals +4.5 (-110) at Los Angeles Rams

Two of the league’s five unbeaten teams clash in this early battle for NFC West supremacy.

The Rams have dominated the series of late, winning eight straight — all by at least 7 points — and going 7-0-1 ATS. Much like the Cowboys, the Rams are in a prime letdown spot coming off a big home win over Tom Brady and the defending Super Bowl champion Tampa Bay Buccaneers.

Dangerous dual-threat QB Kyler Murray and the Cards, who are tied with the Bucs for the league scoring lead at 34.3 points per game, present a different kind of challenge and certainly have enough firepower to keep this one close.

WIN YOUR FANTASY FOOTBALL LEAGUE!

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Las Vegas Raiders +3.5 (-115) at Los Angeles Chargers

QB Derek Carr and the Raiders take their 3-0 record west for a Monday night division tussle with QB Justin Herbert and the 2-1 Bolts.

The Silver & Black won and covered in three of the last four meetings and in what figures to be a close game where Raiders fans will be in the majority at SoFi Stadium, go ahead and take the 3.5 points.

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com. Please gamble responsibly.

Follow @kenpomp on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

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Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage. This information is for entertainment purposes only. We make no representations or warranties as to the accuracy, completeness, or reliability of any content.

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