49ers injury report: QB Jimmy Garoppolo ruled out, TE George Kittle doubtful

49ers rookie quarterback Trey Lance will make his first NFL start this weekend against the Cardinals.

San Francisco 49ers rookie quarterback Trey Lance will make his first NFL start this weekend against the Arizona Cardinals. On the final injury report of Week 5, quarterback Jimmy Garoppolo was ruled out with a calf injury he suffered in the team’s Week 4 loss to the Seattle Seahawks. He was unable to practice all week.

Also ruled out was cornerback K’Waun Williams, who also missed the whole week of practice with a calf injury.

Lance might be without the 49ers’ best offensive player, tight end George Kittle. He also was unable to practice all week with a calf injury and is officially listed as doubtful for the game.

Defensive end Samson Ebukam (hamstring) and defensive tackle Javon Kinlaw (knee) are both questionable. Ebukam only practiced on a limited basis on Friday. Kinlaw was limited all week.

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Cardinals injury report: Byron Murphy ruled out, Chase Edmonds questionable vs. 49ers

The Cardinals will be down one defensive starter and a number of other players will be game-day decisions.

The Arizona Cardinals released their final injury report of Week 5 and they will be down one of their defensive studs of the season.

Cornerback Byron Murphy, who suffered a rib injury last Sunday, was ruled out of the game Sunday against the San Francisco 49ers after missing practice all three days.

Also ruled out was offensive lineman Justin Murray, whose back has been an issue. He was later placed on injured reserve, meaning he will be out for at least three games.

There will be a number of game-day decisions. Among them are running back Chase Edmonds (shoulder) and cornerback Marco Wilson (ribs). Edmonds sat out two days of practice and returned Friday for limited work. Wilson was downgraded each day. He was a full participant Wednesday, limited Thursday and sat out Friday.

Tight end Maxx Williams (shoulder), cornerback Antonio Hamilton (ankle), running back Eno Benjamin (hamstring) and tackle Kelvin Beachum (ribs) will be questionable for the game after getting limited work in practice all week.

How the Cardinals will manage the cornerback position is something that remains to be seen.

Hamilton has played in the slot this year and safety Jalen Thompson also can play in the slot as well. The Cardinals also have Greg Mabin and Luq Barcoo on the practice squad. Rookie Tay Gowan has yet to be active for a game this season.

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49ers injury report: Jimmy Garoppolo, George Kittle miss 2nd practice in a row

The 49ers had six players sit out Thursday, including four starters.

The San Francisco 49ers returned to practice Thursday and released their second injury report of the week. They had six player sit out, including quarterback Jimmy Garoppolo and tight end George Kittle.

Center Alex Mack returned from a day off and left tackle Trent Williams, dealing with a shoulder injury, was a full participant after sitting out Wednesday.

However, several starters sat out. Garoppolo (calf) missed his second day in a row and so did Kittle (calf). Cornerback K’Waun Williams (calf) also sat out for the second day in a row, as well as defensive end Samson Ebukam (hamstring). Defensive tackle D.J. Jones, who was not on the injury report Wednesday, appeared Thursday with a knee injury and was unable to practice. Defensive end Arik Armstead had the day off.

For the second day in a row, defensive tackle Javon Kinlaw (knee), running back Elijah Mitchell (shoulder) and cornerback Josh Norman (chest) were limited.

Did not participate:

  • DE Arik Armstead (rest)
  • DE Samson Ebukam (hamstring)
  • QB Jimmy Garoppolo (calf)
  • TE George Kittle (calf)
  • DT D.J. Jones (knee)
  • CN K’Waun Williams (calf)

Limited participation:

  • DT Javon Kinlaw (knee)
  • RB Elijah Mitchell (shoulder)
  • CB Josh Norman (chest)

Full participation:

  • LT Trent Williams (shoulder)

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Cardinals injury report: Chase Edmonds, Byron Murphy sit out second straight day

The Cardinals had three players out and another six limited for Thursday’s practice.

The Arizona Cardinals released their second injury report of the week on Thursday. There were improvements but also a pair of starters remained sidelined for the second day in a row, while another starter was downgraded.

After 10 sat out Wednesday’s practice, only three were unable to get any work in.

Those who had a day off returned and running back James Conner was back after dealing with something personal.

However, cornerback Byron Murphy (ribs), running back Chase Edmonds (shoulder) and offensive lineman Justin Murray (back) did not practice Thursday. Murphy and Edmonds were out for the second day in a row, while Murray was downgraded from limited to no practicing. Also downgraded was cornerback Marco Wilson (ribs). After being a full participant Wednesday, he was limited Thursday.

Cornerback Antonio Hamilton (ankle), guard Justin Pugh (hip) and tight end Maxx Williams (shoulder) all were unable to practice Wednesday but were upgraded to limited Thursday.

Running back Eno Benjamin (hamstring) and tackle Kelvin Beachum (ribs) were limited for the second day in a row, while linebacker Dennis Gardeck (hand) was a full participant for the second straight day.

Did not participate:

  • RB Chase Edmonds (shoulder)
  • CB Byron Murphy (ribs)
  • OL Justin Murray (back)

Limited participation:

  • CB Antonio Hamilton (ankle)
  • G Justin Pugh (hip)
  • TE Maxx Williams (shoulder)
  • OT Kelvin Beachum (ribs)
  • RB Eno Benjamin (hamstring)
  • CB Marco Wilson (ribs)

Full participation:

  • LB Dennis Gardeck (hand)

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49ers injury report: Jimmy Garoppolo, Trent Williams among 6 DNPs

Six 49ers players did not practice Wednesday and another three were limited.

The San Francisco 49ers kicked off the week of practice preparing for their road games against the Arizona Cardinals and released their first injury report of the week.

Nine players appeared with six who did not participate Wednesday.

Center Alex Mack got the day off for rest, but five are dealing with injuries, including several starters.

It begins with starting quarterback Jimmy Garoppolom who left the 49ers’ 28-21 loss to the Seattle Seahawks with a calf injury. While head coach Kyle Shanahan said he “has a chance” of playing against the Cardinals, Garoppolo did not practice Wednesday. Also out was left tackle Trent Williams, who sustained a shoulder injury. Tight end George Kittle sat out with calf soreness, as did cornerback K’Waun Williams. Defensive end Samson Ebukam was out with a hamstring injury.

Three players were limited in practice — defensive tackle Javon Kinlaw (knee), running back Elijah Mitchell (shoulder) and cornerback Josh Norman (chest). Kinlaw has been dealing with knee soreness all season thus far.

Did not participate:

  • QB Jimmy Garoppolo (calf)
  • C Alex Mack (rest)
  • LT Trent Williams (shoulder)
  • TE George Kittle (calf)
  • CB K’Waun Williams (calf)
  • DE Samson Ebukam (hamstring)

Limited participation:

  • DT Javon Kinlaw (knee)
  • CB Josh Norman (chest)
  • RB Elijah Mitchell (shoulder)

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Cardinals injury report: 16 players appear on first Week 5 report

The Cardinals had 10 players sit out and another four who were limited.

The Arizona Cardinals are 4-0 and have three of the next four games at home, starting with the San Francisco 49ers this weekend. They released their first injury report of the week and it is a whopping 16 players long.

Ten players did not practice, although four players — center Rodney Hudson, receiver DeAndre Hopkins, defensive tackle Corey Peters and linebacker Chandler Jones — had the day of for a rest day. Another — running back James Conner — missed practice for personal reasons.

However, five sat out with injuries. Cornerback Byron Murphy suffered a rib injury in Sunday’s win over the Rams and, while he says he will be fine, he is considered day-to-day. He did not practice Wednesday. Neither did running back Chase Edmonds, who suffered a shoulder injury at the end of his 54-yard run. Cornerback Antonio Hamilton also sat out with an ankle injury he sustained on Sunday. Guard Justin Pugh has a hip injury and tight end Maxx Williams has a shoulder injury. Neither participated in practice.

Receiver A.J. Green was given a partial day off, listed as limited for rest.

Tackle Kelvin Beachum (ribs) practiced on a limited basis for the first time in two weeks. Running back Eno Benjamin (hamstring) was limited, as was offensive lineman Justin Murray (back).

Linebacker Dennis Gardeck (hand) and cornerback Marco Wilson (ribs) were both full participants in practice.

Did not participate:

  • RB James Conner (personal)
  • WR DeAndre Hopkins (rest)
  • DT Corey Peters (rest)
  • C Rodney Hudson (rest)
  • LB Chandler Jones (rest)
  • TE Maxx Williams (shoulder)
  • RB Chase Edmonds (shoulder)
  • G Justin Pugh (hip)
  • CB Byron Murphy (ribs)
  • CB Antonio Hamilton (ankle)

Limited participation:

  • WR A.J. Green (rest)
  • RT Kelvin Beachum (ribs)
  • OL Justin Murray (back)
  • RB Eno Benjamin (hamstring)

Full participation:

  • LB Dennis Gardeck (hand)
  • CB Marco Wilson (ribs)

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