First look: Arizona Cardinals at Carolina Panthers odds and lines

Looking at Sunday’s Arizona Cardinals at Carolina Panthers odds, lines and trends. Here’s what you need to know.

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The Arizona Cardinals (7-7) hit the road in Week 16 to face the Carolina Panthers (3-11). Kickoff is Sunday at 1 p.m. ET from Bank of America Stadium (FOX). Below, we look at Cardinals vs. Panthers odds from BetMGM Sportsbook’s NFL odds before making our expert NFL picks and predictions later in the week.

The Cardinals snapped a 3-game losing streak Sunday, beating the New England Patriots 30-17 at home. Arizona covered as a 6-point favorite and the Over (46) snuck in by a point. RB James Conner rushed for 110 yards and 2 TDs in the victory. The win kept the Cards 1 game behind the co-leading LA Rams and Seattle Seahawks in the NFC West.

The Panthers lost their fourth consecutive game, suffering a 30-14 home loss as 2.5-point favorites to the Dallas Cowboys Sunday. The Over (41.5) hit in this one, too. QB Bryce Young (19 of 28, 219 passing yards, 1 TD) was picked off twice and the Carolina offense mustered only 235 yards. Meanwhile, the defense allowed 410 yards. Dallas QB Cooper Rush (18 of 29, 214 passing yards) threw 3 TD passes against no interceptions and RB Rico Dowdle finished with 149 rushing yards.

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Cardinals at Panthers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Monday at 9:49 p.m. ET.

  • Moneyline (ML): Cardinals -225 (bet $225 to win $100) | Panthers +180 (bet $100 to win $180)
  • Against the spread (ATS): Cardinals -4 (-110) | Panthers +4 (-110)
  • Over/Under (O/U): 47 (O: -115 | U: -105)

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2024 betting stats

  • ML: Cardinals 7-7 | Panthers 3-11
  • ATS: Cardinals 9-5 | Panthers 6-8
  • O/U: Cardinals 6-7-1 | Panthers 10-4

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Cardinals vs. Panthers head-to-head

The Panthers lead the all-time series 14-6, including 2-1 in the playoffs.

They last met in Week 4 of the 2022-23 season, a 26-16 Arizona win in Charlotte as a 2.5-point underdog. QB Kyler Murray (207 passing yards) threw 2 TD passes in the win. It snapped a streak of 6 straight wins in the series by the Panthers. Murray is 1-2 in 3 career starts against the Panthers with 7 TD passes, 3 interceptions and 1 rushing TD.

This will be Young’s first career start against the Cardinals.

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First look: Arizona Cardinals at Carolina Panthers odds and lines

Looking at Sunday’s Arizona Cardinals at Carolina Panthers Week 4 NFL odds, lines and trends. Here’s what you need to know.

The Arizona Cardinals (1-2) are on the road in Week 4 to take on the Carolina Panthers (1-2) Sunday. Kickoff is set for 4:05 p.m. ET at Bank of America Stadium (FOX). Below, we look at Cardinals vs. Panthers odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Cardinals suffered a 20-12 home loss to the Los Angeles Rams in Week 3. They have lost 6 straight games at State Farm Stadium. Arizona fell behind 13-0 and never scored a touchdown despite outgaining Los Angeles (365-339). It was the 11th time the Cards lost to the Rams in their last 12 matchups.

The Panthers picked up their first win of the year Sunday with a 22-14 home victory over the New Orleans Saints. They had a season-high 293 yards of offense and the defense forced 3 turnovers and scored a fumble-recovery touchdown. RB Christian McCaffrey had 108 rushing yards and QB Baker Mayfield had a touchdown pass in the win.

Also seeAll Week 4 odds and lines

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Cardinals at Panthers odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 11:40 a.m. ET.

  • Money line (ML): Cardinals -101 (bet $101 to win $100) | Panthers -117 (bet $117 to win $100)
  • Against the spread (ATS): Cardinals +1.5 (-112) | Panthers -1.5 (-108)
  • Over/Under (O/U): 44.5 (O: -105 | U: -115)

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2022 betting stats

  • ML: Cardinals 1-2 | Panthers 1-2
  • ATS: Cardinals 1-2 | Panthers 1-2
  • O/U: Cardinals 2-1 | Panthers 1-2

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Cardinals vs. Panthers head-to-head

Including 3 postseason matchups, this will be the 20th time the two teams have played. The Panthers have dominated this series 14-5 and have won the last 6 meetings, including twice in the playoffs.

The Cardinals have not beaten the Panthers since 2013; Carolina won last season’s meeting in a 34-10 blowout. New Panthers QB Baker Mayfield is 0-2 against the Cardinals in his career.

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