NFL Prop Bets Payday: 5 Buffalo Bills at New England Patriots predictions for MNF

Highlighting five Monday Night Football prop bet predictions with the Buffalo Bills facing the New England Patriots in Week 16.

The Buffalo Bills (11-3) clash with the rival New England Patriots on Monday Night Football in Week 16. Kickoff at Gillette Stadium in Foxborough, Mass., will be at 8:15 p.m. ET. Below, we give you five prop bet predictions to consider for the Bills-Patriots MNF matchup from the BetMGM game menu.

Also see: Bills at Patriots odds, picks and prediction

Bills at Patriots: Prop bets to make for Monday Night Football

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 11:45 a.m. ET.

Bills RB Devin Singletary OVER 35.5 rushing yards (-110)

Singletary is coming off of one of his best games of the season, having gained 84 yards from scrimmage with a touchdown run on 11 touches (8 carries and 3 receptions). He faces a Patriots rush defense with a total of 436 yards allowed on the ground in their last two games.

The Bills are 7-point favorites in this road matchup, so there’ll likely be plenty of late work for Singletary to run out the clock for the 2020 AFC East champs.

Patriots WR Damiere Byrd OVER 38.5 receiving yards (-110)

Following suit of the thinking above, the Patriots are likely to be trailing for much of the game and will be forced to lean on the league’s 30th-ranked passing offense by yards per game. Byrd has topped 36 receiving yards in seven of his 14 games this year, including 39 yards on 3 receptions in the first meeting with the Bills in Week 8. He’ll have opportunities for a big gain against Buffalo’s prevent defense in the second half.

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Patriots QB Cam Newton OVER 25.5 passing attempts (-105)

Newton attempted 25 passes in the first meeting with the Bills and completed 15 of them for 174 yards without a score. He has topped 25 passes in just three of his last seven games but those were also the only games in which he threw for more than 120 yards.

He’ll need to keep pace with Bills QB Josh Allen‘s 285.7 passing yards per game and the Buffalo defense allows 234.7 yards per game.

Bills RB Zack Moss OVER 53.5 rushing + receiving yards (-115)

Look for Moss to continue the trend of rookie running backs having late-season success with the Bills already locking up the division crown. The third-round pick out of Utah in the 2020 NFL Draft matched a season-high with 81 rushing yards in last week’s 48-19 shellacking of the Denver Broncos.

He has just twice had more than 20 receiving yards through 11 games, but look for offensive coordinator Brian Daboll to experiment with his potential playoff X-factor in what’s projected as a lopsided win.

Bills WR Stefon Diggs to score 2 or touchdowns (+550)

While we like the Bills’ running backs to do most of the heavy lifting in this one, Diggs (and Allen) should continue to star. The offseason trade acquisition from the Minnesota Vikings leads the league with 111 receptions and already has a career-high 1,314 yards, but he has just 5 touchdowns. He has just 2 touchdowns through six games with 100 or more yards.

Diggs should get some more looks in the end zone against a Patriots team already without CB Stephon Gillmore and listing CBs J.C. Jackson (knee) and Jonathan Jones (neck) as questionable.

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