WATCH: Can the Bills get a statement win against the Chiefs? | On Site

USA TODAY Sports reporter Sal Maiorana tees up the Week 5 Sunday Night Football matchup between the Buffalo Bills and Kansas City Chiefs.

Can the Buffalo Bills‘ top-ranked defense stand up to its toughest test of the season in the Kansas City Chiefs and QB Patrick Mahomes on Sunday Night Football in Week 5? USA TODAY Sports reporter Sal Maiorana looks at the Bills vs. Chiefs Sunday Night Football matchup.

The Chiefs are 2.5-point favorites at Tipico Sportsbook.

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