First look: Buffalo Bills at Houston Texans odds and lines

Looking at Sunday’s Buffalo Bills at Houston Texans Week 5 NFL odds, lines and trends. Here’s what you need to know.

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The Buffalo Bills (3-1) meet the Houston Texans (3-1) in a Week 5 Sunday tussle at NRG Stadium. The start time will be at 1 p.m. ET (CBS). Let’s analyze BetMGM Sportsbook’s NFL odds around the Bills vs. Texans odds, and make our expert NFL picks and predictions.

Buffalo, which had yielded just 20 points over its previous 2 games, was touched up for a TD in every quarter of a 35-10 loss at the Baltimore Ravens Sunday. The Bills went just 3 of 13 on 3rd downs and were outgained 427 yards to 236.

On Sunday, Houston bounced back from a Week 3 setback with its 3rd win by 4 points or fewer. Behind QB C.J. Stroud going 27 of 40 for 340 yards, the Texans defeated the Jacksonville Jaguars 24-20.

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Bills at Texans odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Monday at 7:50 a.m. ET.

  • Moneyline: Bills +100 (bet $100 to win $100) | Texans -120 (bet $120 to win $100)
  • Against the spread (ATS): Bills +1.5 (-110) | Texans -1.5 (-110)
  • Over/Under (O/U): 46.5 (O: -115 | U: -105)

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2024 betting stats

  • ML: Bills 3-1 | Texans 3-1
  • ATS: Bills 2-2 | Texans 0-3-1
  • O/U: Bills 2-2 | Texans 1-3

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Bills vs. Texans head-to-head

Buffalo and Houston are meeting for the 1st time since 2021 and for the 12th time overall (includes 1 playoff game). The Texans are 5-2 across the last 7 meetings and lead the all-time series 6-5.

The Texans are 4-2 in games played at home; the 4 wins have been in the last 4 opportunities on home turf.

The last 4 overall meetings have seen Buffalo go 3-1 against the number. The Under has prevailed in 3 straight and is 6-1 across 7 meetings since 2009.

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First look: Buffalo Bills at Baltimore Ravens odds and lines

Looking at Sunday’s Buffalo Bills at Baltimore Ravens Week 4 NFL odds, lines and trends. Here’s what you need to know.

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The Buffalo Bills (3-0) and the Baltimore Ravens (1-2) meet Sunday for a Week 4 game at M&T Bank Stadium. Kickoff is scheduled for 8:20 p.m. ET (NBC/Peacock). Below, we look at Bills vs. Ravens odds from BetMGM Sportsbook’s NFL odds before making our expert NFL picks and predictions later in the week.

The Bills routed the Jacksonville Jaguars 47-0 Monday night as QB Josh Allen tossed 4 TDs and finished with 263 passing yards and no picks. Buffalo easily covered as a 4.5-point favorite as the Over (46.5) cashed. The Bills have won the past 2 games by a margin of 29.0 PPG.

The Ravens started in an 0-2 hole after a loss to the Kansas City Chiefs and a stunning setback at home to the Las Vegas Raiders in Week 2. However, Baltimore went down to Dallas and won 28-25 as a 1-point favorite as the Over (47.5) cashed for the 3rd time in as many games for the Ravens.

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Bills at Ravens odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Tuesday at 3:26 a.m. ET.

  • Moneyline (ML): Bills +110 (bet $100 to win $110) | Ravens -135 (bet $135 to win $100)
  • Against the spread (ATS): Bills +2 (-110) | Ravens -2 (-110)
  • Over/Under (O/U): 46 (O: -110 | U: -110)

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2024 betting stats

  • ML: Bills 3-0 | Ravens 1-2
  • ATS: Bills 2-1 | Ravens 1-2
  • O/U: Bills 2-1 | Ravens 3-0

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Bills vs. Ravens head-to-head

The Ravens lead the all-time series 6-5. They’ve met 9 times since Dec. 31, 2006. Buffalo has won the past 2 meetings, while Baltimore holds a 5-4 SU edge in the 9-game span.

The last meeting was Oct. 2, 2022, a 23-20 win by the Bills in Baltimore, pushing as 3-point favorites with the Under (52) cashing. The total has gone Under in 3 straight meetings, and 5 of the past 6 in the series, including a 17-3 Bills win in an AFC Divisional Round playoff game Jan. 16, 2021, at Highmark Stadium.

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First look: Jacksonville Jaguars at Buffalo Bills odds and lines

Looking at Monday’s Jacksonville Jaguars at Buffalo Bills Week 3 NFL odds, lines and trends. Here’s what you need to know.

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The Jacksonville Jaguars (0-2) travel to meet the Buffalo Bills (2-0) at Highmark Stadium in Week 3 in the first of 2 NFL games Monday night. Kickoff is scheduled for 7:30 p.m. ET (ESPN). Below, we look at Jaguars vs. Bills odds from BetMGM Sportsbook’s NFL odds before making our expert NFL picks and predictions later in the week. The Cincinnati Bengals host the Washington Commanders in the 2nd game of the night at 8:15 p.m. ET (ABC).

The Jaguars head into Buffalo looking for their 1st victory of the season after a pair of one-score losses. Jacksonville blew a Week 1 lead in Miami, falling 20-17, although it did cover as a 3.5-point underdog with the Under (49) cashing.

In the home opener in Week 2, the Jaguars lost as 3-point favorites to the Cleveland Browns 18-13. Jacksonville fell behind 16-3 before making a valiant comeback. The Jags closed the gap to 16-13, but a late safety sealed the win for Cleveland as the Under (41.5) cashed, again.

For the Bills, they were pushed hard in Week 1 by the Arizona Cardinals, eventually holding off the visitors 34-28, although Buffalo failed to cover as a 7-point favorite as the Over (45) cashed.

In Week 2, Buffalo went down to Miami for a Thursday Night Football game, winning 31-10. QB Josh Allen entered that game with an injury to his non-throwing hand, but it didn’t appear to be an issue. He completed 13 of 19 passes for 139 yards and a TD with no picks.

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Jaguars at Bills odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list NFL odds. Lines last updated Tuesday at 2:04 a.m. ET.

  • Moneyline (ML): Jaguars +200 (bet $100 to win $200) | Bills -250 (bet $250 to win $100)
  • Against the spread (ATS): Jaguars +5.5 (-110) | Bills -5.5 (-110)
  • Over/Under (O/U): 46 (O: -110 | U: -110)

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2024 betting stats

  • ML: Jaguars 0-2 | Bills 2-0
  • ATS: Jaguars 1-1 | Bills 1-1
  • O/U: Jaguars 0-2 | Bills 1-1

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Jaguars vs. Bills head-to-head

The Jaguars and Bills have met 10 times since Nov. 22, 2009, and Jacksonville has been a huge thorn in the side of Buffalo.

The Jags have won 3 of the past 4 meetings since Jan. 7, 2018, a 10-3 AFC Wild-Card playoff home win in Jacksonville. The Jags beat the Bills 25-20 in London last season in Week 5, covering as a 5.5-point underdog as the Under (48.5) cashed. The Under has hit in 3 of the past 4 meetings in the series.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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[lawrence-newsletter]

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First look: Buffalo Bills at Miami Dolphins odds and lines

Looking at Thursday’s Buffalo Bills at Miami Dolphins Week 2 NFL odds, lines and trends. Here’s what you need to know.

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The Buffalo Bills (1-0) and Miami Dolphins (1-0) meet for a Week 2 game Thursday. Kickoff from Hard Rock Stadium will be at 8:15 p.m. ET (Prime Video). Below, we look at Bills vs. Dolphins odds from FanDuel Sportsbook before making our expert NFL picks and predictions later in the week.

Buffalo earned a taut 34-28 home win over the Arizona Cardinals Sunday. QB Josh Allen threw for 2 scores and ran for 2 more in a game that saw the Bills overcome 9 penalties. Buffalo outgained Arizona 352 yards to 270.

The Dolphins also registered a Week 1 victory. They got a 52-yard Jason Sanders field goal as time expired to earn a 20-17 win over the Jacksonville Jaguars. The field goal, one of 2 Sanders 3-pointers in the final quarter, capped off a Miami comeback after the Jaguars had scored the game’s 1st 14 points.

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Bills at Dolphins odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 7:23 a.m. ET.

  • Moneyline: Bills +108 (bet $100 to win $108) | Dolphins -130 (bet $130 to win $100)
  • Against the spread (ATS): Bills +1.5 (-110) | Dolphins -1.5 (-110)
  • Over/Under (O/U): 50.5 (O: -110 | U: -110)

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2024 betting stats

  • ML: Bills 1-0 | Dolphins 1-0
  • ATS: Bills 0-1 | Dolphins 0-1
  • O/U: Bills 1-0 | Dolphins 0-1

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Bills at Dolphins head-to-head

Buffalo and Miami are meeting for the 122nd time (includes 5 postseason meetings). The Dolphins own an all-time edge of 62-58-1.

The Bills swept 2 games in the 2023 season series and have won 4 in a row against Miami. Last year’s contests (Oct. 1, Jan. 7) were both ATS victories for Buffalo.

The last dozen meetings have seen Buffalo dominate with an 11-1 straight-up (SU) mark. Since 2019, the Bills are 4-1 SU and ATS at Miami.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW. Follow SportsbookWire on Twitter/X and like us on Facebook.

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[lawrence-newsletter]

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First look: Arizona Cardinals at Buffalo Bills odds and lines

Looking at Sunday’s Arizona Cardinals at Buffalo Bills Week 1 NFL odds, lines and trends. Here’s what you need to know.

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The Arizona Cardinals and Buffalo Bills open their seasons Sunday. Kickoff from Highmark Stadium is scheduled for 1 p.m. ET (CBS). Below, we look at Cardinals vs. Bills odds from BetMGM Sportsbook before making our expert NFL picks and predictions later in the week.

The Cardinals are coming off a second consecutive 4-win season, but are much more optimistic this time around, as QB Kyler Murray is healthy and played well in the 2nd half of last season.

The Bills are coming off another season winning the AFC East and then losing in the playoffs to the Kansas City Chiefs. They went 11-6 in the regular season and lost to the Chiefs in the divisional round of the playoffs. QB Josh Allen had 44 combined passing and rushing touchdowns last season.

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Cardinals at Bills odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 11:10 a.m. ET.

  • Moneyline (ML): Cardinals +225 (bet $100 to win $225) | Bills -275 (bet $275 to win $100)
  • Against the spread (ATS): Cardinals +6 (-110) | Bills -6 (-110)
  • Over/Under (O/U): 48 (O: -115 | U: -105)

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2023 betting stats

  • ML: Cardinals 4-13 | Bills 12-7
  • ATS: Cardinals 9-8 | Bills 8-11
  • O/U: Cardinals 10-7 | Bills 8-11

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Cardinals vs. Bills head-to-head

The Cardinals and Bills are infrequent opponents. The Cardinals won the last matchup 32-30 in Arizona in 2020 on a last-second touchdown pass from Murray to WR DeAndre Hopkins, known in Arizona as the Hail Murray.

The Bills lead the all-time series 7-5. The only time the Bills have lost to the Cardinals at home was in 1971, their first-ever meeting, when the Cardinals played in St. Louis.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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[lawrence-newsletter]

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First look: Buffalo Bills at Cincinnati Bengals odds and lines

Looking at Sunday’s Buffalo Bills at Cincinnati Bengals Week 9 NFL odds, lines and trends. Here’s what you need to know.

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The Cincinnati Bengals (4-3) welcome the Buffalo Bills (5-3) to Paycor Stadium Sunday. Kickoff is set for 8:20 p.m. ET (NBC). Below, we look at Bills vs. Bengals odds from BetMGM Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

The Bengals started off the season 1-3 straight up and 0-3-1 against the spread (ATS). Since then, they are 3-0 straight up and ATS. The health of QB Joe Burrow coupled with a timely bye week have helped immensely. Cincinnati beat the San Francisco 49ers 31-17 on the road in Week 8, covering as a 4.5-point underdog.

The Bills beat the Tampa Bay Buccaneers on Thursday Night Football in Week 8, 24-18, yet are 0-4 ATS over their last 4 games. Buffalo is 2-2 straight up over that span. It scored 30-plus points in 3 of its 1st 4 games but hasn’t hit that mark in its last 4. The Bills are led by QB Josh Allen, who has 2,165 passing yards and 22 total touchdowns on the season.

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Bills at Bengals odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 2 p.m. ET.

  • Moneyline (ML): Bills +130 (bet $100 to win $130) | Bengals -155 (bet $155 to win $100)
  • Against the spread (ATS): Bills +3 (-115) | Bengals -3 (-105)
  • Over/Under (O/U): 48.5 (O: -110 | U: -110)

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2023 betting stats

  • ML: Bengals 4-3 | Bills 5-3
  • ATS: Bengals 3-3-1 | Bills 3-5
  • O/U: Bengals 3-4 | Bills 3-5

Bills vs. Bengals head-to-head

The Bengals and Bills have only played 33 times throughout their history, with Buffalo holding a slight lead in the series 17-16.

As many remember, the Bengals and Bills were in a high-profile Monday Night Football clash in January of 2023, but that game was ultimately canceled. S Damar Hamlin, who went into cardiac arrest after a blow to the chest on the field in that game, should be active on SNF.

The Bengals and Bills have alternated winning and losing over their last 5 games, with the Bengals beating the Bills 27-10 on the road in the playoffs last season.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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First look: Tampa Bay Buccaneers at Buffalo Bills odds and lines

Looking at Thursday’s Tampa Bay Buccaneers at Buffalo Bills Week 8 NFL odds, lines and trends. Here’s what you need to know.

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The Tampa Bay Buccaneers (3-3) and Buffalo Bills (4-3) meet for Thursday Night Football at Highmark Stadium. Kickoff is scheduled for 8:15 p.m. ET (Prime Video). Below, we look at Buccaneers vs. Bills odds from FanDuel Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

The Buccaneers were on the short end of a 16-13 loss at home against the Atlanta Falcons in Week 7, losing on a last-second field goal. Tampa Bay has dropped 3 of the past 4 games, while also going 1-3 against the spread (ATS). The Under has cashed in 4 in a row, and 5 of 6 games overall.

The Bills are coming off a stunning 29-25 road loss against the New England Patriots as 8.5-point favorites. The 29 points allowed were actually the most for Buffalo all season. Buffalo has dropped 2 of the past 3 games, while failing to cover each of the previous 3 outings.

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Buccaneers at Bills odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 9:45 a.m. ET.

  • Moneyline (ML): Buccaneers +320 (bet $100 to win $320) | Bills -405 (bet $405 to win $100)
  • Against the spread (ATS): Buccaneers +7.5 (-105) | Bills -7.5 (-115)
  • Over/Under (O/U): 41.5 (O: -110 | U: -110)

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2023 betting stats

  • ML: Buccaneers 3-3 | Bills 4-3
  • ATS: Buccaneers 3-3 | Bills 3-4
  • O/U: Buccaneers 1-5 | Bills 3-4

Buccaneers at Bills head-to-head

These teams last met on Dec. 12, 2021, with the Buccaneers coming away with a memorable 33-27 overtime victory as 3.5-point home favorites behind future Hall-of-Fame QB and Bills nemesis Tom Brady. The Over (53) cashed in that game, and is 3-1 in the past 4 meetings dating back to Sept. 20, 2009.

The last time these teams met in Western New York, the Bills came away with a 30-27 win while pushing at most shops as 3-point favorites.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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[lawrence-newsletter]

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First look: Buffalo Bills at New England Patriots odds and lines

Looking at Sunday’s Buffalo Bills at New England Patriots NFL odds, lines and trends. Here’s what you need to know.

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The Buffalo Bills (4-2) and New England Patriots (1-5) meet Sunday in a 1 p.m. ET (CBS) kickoff at Gillette Stadium in Foxborough. Below, we look at Bills vs. Patriots odds from BetMGM Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

Buffalo bounced back from an Oct. 8 loss to the Jacksonville Jaguars with a Sunday triumph over the New York Giants. The Bills allowed just 3 field goals in a 14-9 win, but a minus-2 in turnovers and some stalls on offense kept Buffalo from covering a -15.5 spread.

The Patriots dropped their 3rd straight game, losing 21-17 at the Las Vegas Raiders Sunday. A New England offense averaging just 4.6 yards per play (29th NFL) has now scored just 20 points over 3 October games.

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Bills at Patriots odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 1:39 p.m. ET.

  • Moneyline: Bills -450 (bet $450 to win $100) | Patriots +350 (bet $100 to win $350)
  • Against the spread (ATS): Bills -9.5 (-110) | Patriots +9.5 (-110)
  • Over/Under (O/U): 42 (O: -110 | U: -110)

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2023 betting stats

  • ML: Bills 4-2 | Patriots 1-5
  • ATS: Bills 3-3 | Patriots 1-5
  • O/U: Bills 2-4 | Patriots 1-5

Bills vs. Patriots head-to-head

The Buffalo-New England rivalry has been played 127 times (including 2 postseason games). The Patriots lead 77-49-1.

The Bills swept 2 games from the Pats last season, and Buffalo has won 4 in a row and 6 of the last 7 meetings.

Over the last 9 meetings, Buffalo is 6-3 ATS. The Bills have won 3 in a row ATS in Foxborough.

The O/U has been a near-level proposition over many years of games at New England. The Over is 9-10-1 across the last 20 Patriots home games against the Bills.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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[lawrence-newsletter]

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First look: New York Giants at Buffalo Bills odds and lines

Looking at Sunday’s New York Giants at Buffalo Bills Week 6 NFL odds, lines and trends. Here’s what you need to know.

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The New York Giants (1-4) visit the Buffalo Bills (3-2) on Sunday Night Football in Week 6. Kickoff from Highmark Stadium is at 8:20 p.m. ET (NBC). Below, we look at Giants vs. Bills odds from BetMGM Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

The Giants failed to cover as 13-point road underdogs in a 31-16 loss at the Miami Dolphins in Week 5. The Under (48) cashed in New York’s 3rd consecutive loss.

The Bills stumbled in London Sunday, losing 25-20 to the Jacksonville Jaguars as 5.5-point favorites. The loss snapped a 3-game win streak.

FOOTBALL NEVER STOPS
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Giants at Bills odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 8:26 a.m. ET.

  • Moneyline (ML): Giants +600 (bet $100 to win $600) | Bills -900 (bet $900 to win $100)
  • Against the spread (ATS): Giants +14.5  (-110) | Bills -14.5 (-110)
  • Over/Under (O/U): 46.5 (O: -110 | U: -110)

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2023 betting stats

  • ML: Giants 1-4 | Bills 3-2
  • ATS: Giants 0-5 | Bills 3-2
  • O/U: Giants 1-4 | Bills 2-3

Giants vs. Bills head-to-head

The Giants and Bills have faced each other only 14 times in an all-time series that dates back to 1970 and includes a meeting in Super Bowl XXV.  The series is split 7-7, but the Giants won the Super Bowl 20-19.

Buffalo won 28-14 when these teams met in 2019, covering as a 1-point favorite as the Under (44.5) cashed. New York had won the 3 previous meetings in 2007, 2011 and 2015.

Bills QB Josh Allen was the starter in that 2019 win. Giants QB Daniel Jones was on the Giants’ roster but was not the starter at the time.

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First look: Jacksonville Jaguars vs. Buffalo Bills odds and lines

Looking at Sunday’s Jacksonville Jaguars vs. Buffalo Bills Week 5 NFL odds, lines and trends. Here’s what you need to know.

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The Jacksonville Jaguars (2-2) faceoff against the Buffalo Bills (3-1) on Sunday in London. Kickoff from Tottenham Hotspur Stadium is set for 9:30 a.m. ET (NFL Network). Below, we look at Jaguars vs. Bills odds from BetMGM Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

Jacksonville enters off a 23-7 victory over the Atlanta Falcons in London in Week 4, covering as a 3.5-point favorite. QB Trevor Lawrence went 23 of 30 passing for 207 yards and a touchdown with his top target being WR Christian Kirk who had 8 receptions off 12 targets for 84 yards. WR Calvin Ridley scored the TD but had just 2 receptions for 38 yards. The Jags might have an advantage on Sunday, having already been in London for a week.

The Bills took down the Miami Dolphins 48-20 Sunday, covering as 3-point favorites and continuing their offensive dominance. Buffalo has scored at least 37 points in its last 3 games. QB Josh Allen led the way going 21 of 25 passing for 320 yards and 4 TDs while also adding a score on the ground. WR Stefon Diggs had 6 receptions for 120 yards and 3 TDs.

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Jaguars vs. Bills odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 11:17 a.m. ET.

  • Moneyline (ML): Jaguars +200 (bet $100 to win $200) | Bills -250 (bet $250 to win $100)
  • Against the spread (ATS): Jaguars +5.5 (-110) | Bills -5.5 (-110)
  • Over/Under (O/U): 48 (O: -110 | U: -110)

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2023 betting stats

  • ML: Jaguars 2-2 | Bills 3-1
  • ATS: Jaguars 2-2 | Bills 3-1
  • O/U: Jaguars 2-2 | Bills 2-2

Jaguars vs. Bills head-to-head

The last time these teams faced off was a 9-6 Jacksonville victory as 14.5-point underdogs in Nov. 2021. The Bills are 4-3 both straight up and against the spread (ATS) in the last 7 matchups dating back to 2012 with the Over cashing in 5 of those games.

Play our free daily Pick’em Challenge and win! Play now!

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow @seth_orlemann on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

Access more NFL coverage:

TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CommandersWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWireTitansWire | VikingsWire | DraftWire | TouchdownWire | ListWire

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