Tampa Bay Buccaneers at Philadelphia Eagles odds, picks and prediction

Analyzing Thursday’s Tampa Bay Buccaneers at Philadelphia Eagles Week 6 odds and lines, with expert NFL picks, predictions and best bets.

Week 6 of the NFL season kicks off with a Thursday night game between the Tamp Bay Buccaneers (4-1) and Philadelphia Eagles (2-3). Kickoff is 8:20 p.m. ET at Lincoln Financial Field. Below, we look at the Buccaneers vs. Eagles odds and lines, and make our best NFL picks, predictions and bets.

The Buccaneers put on an offensive clinic in Week 5. They beat the Miami Dolphins 45-17, and QB Tom Brady had 411 passing yards and five touchdown passes, leading to being named NFC Offensive Player of the Week. Both WR Antonio Brown and Mike Evans had over 100 receiving yards.

The Eagles snapped a three-game losing streak Sunday rallying back from a 15-3 deficit to defeat the Carolina Panthers 21-18. QB Jalen Hurts rushed for two touchdowns, including a six-yard go-ahead score with 2:38 left in the game. They held the Panthers to 267 yards and 5-for-15 on third down.

Buccaneers at Eagles odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 7:45 a.m. ET.

  • Money line: Buccaneers -290 (bet $290 to win $100) | Eagles +225 (bet $100 to win $225)
  • Against the spread (ATS): Buccaneers -6.5 (-112) | Eagles +6.5 (-108)
  • Over/Under (O/U): 52.5 (O: -110 | U: -110)

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Buccaneers at Eagles key injuries

Buccaneers

  • LB Lavonte David (ankle) out
  • TE Rob Gronkowski (ribs) out
  • Antoine Winfield Jr. (concussion) out
  • OLB Jason Pierre-Paul (shoulder/hand) questionable

Eagles

  • OT Lane Johnson (personal matter) out
  • TE Dallas Goedert (COVID-19) questionable

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Buccaneers at Eagles odds, lines, predictions and picks

Prediction

Buccaneers 31, Eagles 17

Money line

The Eagles are 1-3 against teams with winning records when they play them. They have not yet won a game this season at home.

The Bucs are No. 1 in total offense and No. 3 in points scored per game. Their only loss this season was to the now 4-1 Los Angeles Rams.

Take the BUCCANEERS (-290).

Against the spread

Both the Eagles and the Buccaneers are 2-3 ATS on the season, but the Eagles are 0-2 ATS at home. The Bucs, though, are 0-2 ATS on the road.

The Bucs have played in two prime-time games so far this time, winning both by only two points each. However, they put up 48 points against the 12th-ranked Atlanta Falcons defense. The Eagles are ranked ninth in total defense.

Brady has 15 touchdown passes to only two interceptions in five games. He should pick apart the Eagles defense.

Take the BUCCANEERS -6.5 (-112).

Over/Under

Four of the Buccaneers’ five games this season have hit the Over. Two of the Eagles’ five games have.

The Bucs have allowed only 17 points in each of their last two games. They will limit Hurts and the Philadelphia offense, keeping their total low enough that, even if they put up 30 points, it won’t be enough to get to the projected total. Brady is also playing in a short week after injuring his throwing thumb Sunday. It has been heavily wrapped all week, and it’s going to be a factor.

Take UNDER 52.5 (-110).

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