First look: Cleveland Browns at Buffalo Bills odds and lines

Looking at Sunday’s Cleveland Browns at Buffalo Bills Week 11 NFL odds, lines and trends. Here’s what you need to know.

The Cleveland Browns (3-6) travel to meet the Buffalo Bills (6-3) for a Week 11 matchup at Highmark Stadium in Orchard Park, N.Y. Kickoff is scheduled for 1 p.m. ET (CBS). Below, we look at Browns vs. Bills odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Browns were paddled 39-17 in Miami despite having 2 weeks to prepare after a bye. The defense has now allowed 30 or more points in 3 of the past 5 games overall, with the Over 6-2-1 in 9 games this season.

The Bills were on the short end of a wild 33-30 overtime loss against the Minnesota Vikings in Week 10. Buffalo held a 27-23 lead with less than a minute to go, but QB Josh Allen fumbled on a sneak to get out of his own end zone, and the Vikings took the 30-27 lead. The Bills forced OT, but Minnesota took a 33-30 lead in the extra session. Buffalo has a chance to tie, or even take the lead, but Allen was picked off in the end zone by CB Patrick Peterson. As such, Buffalo fell out of first place in the AFC East.

Also see: All Week 11 odds and lines

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Browns at Bills odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 7:40 a.m. ET.

  • Moneyline (ML): Browns +320 (bet $100 to win $320) | Bills -390 (bet $390 to win $100)
  • Against the spread (ATS): Browns +9.5 (-111) | Bills -9.5 (-109)
  • Over/Under (O/U): 47.5 (O: -110 | U: -110)

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2022 betting stats

  • ML: Browns 3-6 | Bills 6-3
  • ATS: Browns 4-5 | Bills 4-4-1
  • O/U: Browns 6-2-1 | Bills 2-7

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Browns at Bills head-to-head

The Browns won the most-recent meeting against the Bills in Cleveland, 19-16, back on Nov. 10, 2019. Buffalo has won its past 3 home games against Cleveland, with the Bills going 4-1-1 ATS in the previous 6 meetings overall. The home team is 3-0-1 ATS in the past 4 in the series, too.

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