Buffalo Bills at Cincinnati Bengals odds, picks and predictions

Analyzing Monday’s Buffalo Bills at Cincinnati Bengals odds and lines, with expert NFL picks, predictions and best bets.

The Buffalo Bills (12-3) battle the Cincinnati Bengals (11-4) at Paycor Stadium on Monday night. Kickoff from Cincinnati is set for 8:30 p.m. ET (ESPN). Below, we analyze Tipico Sportsbook’s lines around the Bills vs. Bengals odds, and make our expert NFL picks and predictions.

The Bills are on a 6-game winning streak, most recently blowing out the Bears 35-13, covering as 14-point road favorites. Buffalo is 7-7-1 against the spread (ATS) and has only covered 3 times in their last 9 games. The Bills have the 4th-best offense in the NFL for points scored per game (28) and the 2nd-best defense for points allowed (17.5 PPG).

Cincinnati beat New England 22-18 last week, extending its win streak to 7 games and covering as 3-point road favorites. The Bengals have covered 9 of their last 10 games are are 12-3 ATS overall. The offense ranks 5th in passing yards per game (269.2) while the defense ranks 7th in rushing yards allowed per game (106.4).

FOOTBALL NEVER STOPS
Live games, analysis and more 7 days a week: Get ESPN+

Bills at Bengals odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 2:31 p.m. ET.

  • Moneyline (ML): Bills -120 (bet $120 to win $100) | Bengals +100 (bet $100 to win $100)
  • Against the spread (ATS): Bills -1.5 (-108) | Bengals +1.5 (-112)
  • Over/Under (O/U): 49.5 (O: -109 | U: -111)

Catch the excitement and bet with Tipico

Double Down, Ohio! Deposit $200, Get $250. Bet now!

In Colorado and New Jersey, claim your 100% Deposit Match up to $250 now. Bet now! 21+, see Tipico.com for Terms and Conditions.

Bills at Bengals key injuries

Bills

  • DE Boogie Basham (calf) questionable
  • TE Dawson Knox (hip) questionable
  • OLB Matt Milano (knee) questionable
  • NT Jordan Phillips (shoulder) questionable
  • FS Jordan Poyer (knee) questionable

Bengals

  • OT La’el Collins (knee) out
  • DE Sam Hubbard (calf) questionable

Play our free daily Pick’em Challenge and win! Play now!

Bills at Bengals picks and predictions

Prediction

Bengals 27, Bills 20

Moneyline

BET BENGALS (+100).

This season, Buffalo is ranked 30th in turnovers (24), whereas Cincinnati has a top-10 defense in the takeaway category (20).

The Bills QB Josh Allen has thrown multiple interceptions 4 times in his previous 9 games. This could lead to a few game-changing turnovers and is becoming too consistent for the MVP-hopeful quarterback.

Against the spread

PASS.

The underdog is 7-2 ATS in the last 9 meetings between these 2 which bodes well for a Cincinnati win. While the Bengals have been hot against the spread this season and worthy of a play in this primetime battle, the moneyline is a more preferable play.

Over/Under

LEAN UNDER 49.5 (-111).

The Bills are 5-10 O/U and the Bengals are 5-9-1 O/U with just 1 of their previous 5 games hitting the Over. In a game that is predicted to be rainy, with 2 top-10 rush defenses, points will be at a premium.

The Under is 7-1 in the Bills’ last 8 road games and 7-0 in the Bengals’ last 7 games against a team with a winning record.

Want action on this NFL game or any other matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in OH, CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow @seth_orlemann on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Access more NFL coverage:

BetFTW | TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CommandersWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWireTitansWire | VikingsWire | DraftWire | TouchdownWire | ListWire

[lawrence-newsletter]

[lawrence-auto-related count=3 category=1367]

First look: Buffalo Bills at Cincinnati Bengals odds and lines

Looking at Monday’s Buffalo Bills at Cincinnati Bengals Week 17 NFL odds, lines and trends. Here’s what you need to know.

The final game of the NFL’s Week 17 schedule has the Buffalo Bills (12-3) on the road to take on the Cincinnati Bengals (11-4) on Monday. Kickoff at Paycor Stadium in Cincinnati is at 8:15 p.m. ET  (ESPN). Below, we look at Bills vs. Bengals odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Bills are riding a 6-game winning streak. They are coming off a 35-13 road win over the Chicago Bears in Week 16, easily covering the 8-point spread as favorites.

The Bengals have won 7 in a row. They are coming off a 22-18 road win over the New England Patriots as 3-point favorites.

FOOTBALL NEVER STOPS
Live games, analysis and more 7 days a week: Get ESPN+

Bills at Bengals odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 11:44 a.m. ET.

  • Moneyline (ML): Bills -120 (bet $120 to win $100) | Bengals -110 (bet $110 to win $100)
  • Against the spread (ATS): Bills -1 (-111) | Bengals +1 (-109)
  • Over/Under (O/U): 49.5 (O: -111 | U: -109)

2022 betting stats

  • ML: Bills 12-3 | Bengals 11-4
  • ATS: Bills 7-7-1 | Bengals 12-3
  • O/U: Bills 5-10 | Bengals 5-9-1

Play our free daily Pick’em Challenge and win! Play now!

Bills vs. Bengals head-to-head

Dating back to 1968, the Bills and Bengals have faced each other 30 times in the regular season and twice in the playoffs. The Bengals are 2-0 against the Bills all-time in the postseason, but the Bills hold a 17-13 advantage in the regular season.

It is their 1st matchup since 2019, which the Bills won 21-17 at home.

They have alternated wins in the last 4 matchups since 2015.

Bills QB Josh Allen is 1-0 against the Bengals. It will be Bengals QB Joe Burrow‘s 1st career start against the Bills.

Want action on this NFL game or any other matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in OH, CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow Jess Root on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Access more NFL coverage:

BetFTW | TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CommandersWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWireTitansWire | VikingsWire | DraftWire | TouchdownWire | ListWire

[lawrence-newsletter]

[lawrence-auto-related count=3 category=1367]