The Seattle Mariners (19-23) and San Francisco Giants (22-21) close out a two-game, interleague series at Oracle Park Wednesday. First pitch is slated for 9:45 p.m. ET. Below, we analyze the Mariners-Giants MLB betting odds and lines, with picks and best bets.
Mariners at Giants: Projected starting pitchers
LHP Nick Margevicius vs. LHP Tyler Anderson
Margevicius owns a 3.86 ERA and 1.13 WHIP through 25 2/3 innings. He started the season in the Mariner bullpen but has been in the starting rotation since Aug. 8.
- Hasn’t pitched since Aug. 28.
Anderson makes up the home half of this lefty-lefty duel. The 30-year-old veteran has posted a 5.18 ERA and 1.45 WHIP through seven starts and two relief appearances this season.
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Mariners at Giants: Key injuries
(Get the latest injury news here.)
Mariners
- C Tom Murphy (foot) out
- OF Julio Rodriguez (wrist) out
Giants
- OF Joey Rickard (elbow) out
Also see: BaseballHQ Fantasy Baseball
Mariners at Giants: Odds, lines, picks and betting tips
MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 12:15 p.m. ET.
Moneyline (ML)
The Giants (-143) have yielded 5.1 runs per game in 2020, but analytics — mostly on the starting pitcher side — peg that as an overshot by about a quarter run. That likely doesn’t apply here, though. Anderson’s 5-plus ERA is for real.
Margevicius has been sharp enough in three of his four starts to warrant a bit of optimism. He has faced some capable offensive clubs in those three workable turns.
MARINERS (+130) is a workable price in taking the underdog on Wednesday.
New to sports betting? A winning $50 bet on the Mariners returns a profit of $65.
Run line/Against the spread (ATS)
Seattle has averaged 5.6 RPG over five games in September. The Mariners are 10-4 with a .779 OPS over their last 14 games.
The Giants held the Mariners scoreless over the final six innings of a 6-5 victory in Tuesday’s series opener. Three top San Francisco bullpen options were utilized and figure to be unavailable or low on reserves heading into Wednesday’s game. Both bullpens are shaky, but give the edge to the Mariners in this contest. MARINERS +1.5 (-162) is a nice price on the run line.
Over/Under (O/U)
Not enough wiggle room on a murky overall picture of the game flow here. Steer clear of the Over 9 (-110)/Under 9 (-110) proposition.
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