Appalachian State at Clemson odds, picks and predictions

Analyzing Saturday’s Appalachian State at Clemson odds and lines, with college football expert picks, predictions and best bets.

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The No. 22 Clemson Tigers (0-1) welcome the Appalachian State Mountaineers (1-0) to Memorial Stadium Saturday. Kickoff is set for 8 p.m. ET (ACC Network). Below, we analyze FanDuel Sportsbook’s lines around the Appalachian State vs. Clemson odds, and make our expert college football picks and predictions.

Clemson is No. 22 in the US LBM Coaches Poll. It was given a nearly-impossible task in Week 1 — upset Georgia — and it did anything other than that. The Tigers lost 34-3 Aug. 31, failing to cover as 10.5-point underdogs on a neutral field. Clemson started off strong and was down just 6-0 at the half; however, it couldn’t keep pace with the size and strength of the Bulldogs in the trenches. It should get an easier Week 2 matchup.

App State, which plays in the Sun Belt, throttled Eastern Tennessee State to the tune of 38-10 Aug. 31, but failed to cover as a 32.5-point favorite. The Mountaineers ended with a stellar 326 yards through the air and another 174 on the ground. QB Joey Aguilar, who had 33 passing touchdowns last season, was the star of the show and completed 22 of 36 passes.

– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports

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Appalachian State at Clemson odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:55 a.m. ET.

  • Moneyline (ML): Appalachian State +550 (bet $100 to win $550) | Clemson -820 (bet $820 to win $100)
  • Against the spread (ATS): Appalachian State +16.5 (-105) | Clemson -16.5 (-115)
  • Over/Under (O/U): 52.5 (O: -110 | U: -110)

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Appalachian State at Clemson picks and predictions

Prediction

Clemson 31, App State 24

Moneyline

PASS.

Clemson (-820) is way too expensive, especially given how poor it played Aug. 31. App State may be worth a moneyline play, but the spread has the better value here.

Against the spread

BET APPALACHIAN STATE +16.5 (-105).

The Mountaineers didn’t cover but looked good in their first game of the season. They didn’t have an interception or a fumble and played a clean game. App State finished last season 9-5 and 6-2 in conference play. It lost by 6 in 2OT to then-No. 17 North Carolina Sept. 9, 2023, and beat top-25 James Madison Nov. 18. It should continue its success against top opponents.

Clemson was destroyed by Georgia, and QB Cade Klubnik threw for just 142 yards with an interception. He didn’t show enough, and the Tigers couldn’t get the ground game going. While one can discount that it was taking on Georgia, it didn’t show enough to suggest it can cover this size of a spread against a capable Sun Belt side.

Take APPALACHIAN STATE +16.5 (-105).

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Over/Under

BET OVER 52.5 (-110).

App State put up 38 points in Week 1 and has a second-year QB who was in the system last season and plays at a fast pace. It should be able to produce against Clemson, a side that gave up 28 in the 2nd half to Georgia.

The Tigers should be craving some easier competition, and Klubnik did throw for a combined 7 touchdowns in the 2 non-Power 4 games Clemson played a season ago. Expect him to be able to get his rhythm back.

Take OVER 52.5 (-110).

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