Philadelphia 76ers at Detroit Pistons odds, picks and predictions

Analyzing Sunday’s Philadelphia 76ers at Detroit Pistons odds and lines, with NBA expert picks, predictions and best bets.

The Philadelphia 76ers (23-15) and Detroit Pistons (11-31) meet Sunday at Little Caesars Arena. Tip-off is scheduled for 3 p.m. ET. Below, we analyze Tipico Sportsbook’s lines around the 76ers vs. Pistons odds, and make our expert NBA picks and predictions.

The 76ers failed to cover the spread as 5-point home favorites in a 126-112 loss vs. the Chicago Bulls Friday. Bulls C Nikola Vucevic had a triple-double with 19 points, 18 rebounds and 10 assists as Philadelphia’s 11-game home winning streak came to an end. The 76ers are 14-5 against the spread (ATS) vs. the Pistons in their last 19 head-to-head meetings.

The Pistons failed to cover as 1.5-point underdogs 121-109 at the San Antonio Spurs Friday. F Bojan Bogdanovic scored a team-high 21 points as Detroit fell short in its attempt to win back-to-back games for just the 2nd time this season. The Pistons are 0-3-2 ATS in their last 5 home games after coming back from a road trip of 7 or more days.

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76ers at Pistons odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:34 a.m. ET.

  • Moneyline (ML): 76ers -220 (bet $220 to win $100) | Pistons +190 (bet $100 to win $190)
  • Against the spread (ATS): 76ers -5.5 (-110) | Pistons +5.5 (-110)
  • Over/Under (O/U): 229.5 (O: -112 | U: -108)

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76ers at Pistons key injuries

76ers

  • Marvin Bagley III (hand) out
  • C Joel Embiid (foot) out
  • F P.J. Tucker (illness) out

Pistons

  • C Jalen Duren (ankle) questionable
  • F Isaiah Livers (shoulder) out

For most recent updates: Official NBA injury report.

76ers at Pistons picks and predictions

Prediction

76ers 124, Pistons 114

Moneyline

PASS.

The 76ers (-220) should win, but there is no need to risk more than 2 times your potential profit on the ML when Philadelphia should be able to win by margin. Bet the spread or total instead.

Against the spread

BET 76ERS -5.5 (-110).

Even without Embiid, the 76ers still have a much more talented roster than the Pistons. The trio of G James Harden, G Tyrese Maxey and F Tobias Harris should be able to carry the load offensively and win by margin vs. a Pistons team that just wrapped up a 5-game road trip. The 76ers are 6-4 without Embiid in the lineup this season and should be able to run up the score vs. the Pistons who are ranked dead-last in the NBA in defensive efficiency at home. Lay the points.

Over/Under

BET OVER 229.5 (-112).

The Over is 7-1 in Philadelphia’s last 8 games and 7-1-1 in the last 9 head-to-head meetings between these teams in Detroit. The 76ers should score with ease vs. Detroit’s league-worst defense at home and no Embiid in the paint will make it easier for the Pistons to drive the lane and put up points.

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