Philadelphia 76ers at Cleveland Cavaliers odds, picks and predictions

Analyzing Wednesday’s Philadelphia 76ers at Cleveland Cavaliers odds and lines, with NBA expert picks, predictions and best bets.

The Philadelphia 76ers (45-22) take on the Cleveland Cavaliers (44-27) Wednesday at Rocket Mortgage FieldHouse. Tip-off is scheduled for 7:30 p.m. ET (ESPN). Below, we analyze Tipico Sportsbook’s lines around the 76ers vs. Cavaliers odds, and make our expert NBA picks and predictions.

The 76ers defeated the Washington Wizards 112-93 Sunday and covered as 7-point home favorites. Philadelphia is currently on a 5-game win streak and is 3 games ahead of Cleveland for the No. 3 seed in the Eastern Conference.

The Cavaliers covered as 5.5-point road favorites a 120-104 win over the Charlotte Hornets Tuesday. Cleveland has won 6 of its last 8 contests.

This will be the third season meeting between the 76ers and the Cavaliers. They split the first two games straight up and against the spread (with the home team winning and covering in both) and the Over/Under going 1-1.

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76ers at Cavaliers odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:30 a.m. ET.

  • Moneyline (ML): 76ers -140 (bet $140 to win $100) | Cavaliers +120 (bet $100 to win $120)
  • Against the spread (ATS): 76ers -2.5 (-112) | Cavaliers +2.5 (-108)
  • Over/Under (O/U): 219.5 (O: -115 | U: -105)

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76ers at Cavaliers key injuries

76ers

  • None

Cavaliers

  • Not yet submitted

For most recent updates: Official NBA injury report.

76ers at Cavaliers picks and predictions

Prediction

Cavaliers 114, 76ers 110

Moneyline

It feels like Cleveland deliberately rested G Donovan Mitchell on Tuesday to play on Wednesday, so I’m taking the CAVALIERS (+120) in this pivotal matchup. However, it may be worth waiting for the Cavs’ injury report to be released because if Mitchell and C Jarrett Allen are ruled out again then I’d lean toward the 76ers.

Against the spread

CAVALIERS +2.5 (-108) is the ideal pick assuming Cleveland gets Mitchell and/or Allen back in the lineup. The Cavaliers are 28-7 at home this season and this is an important game if they hope to move up to the No. 3 seed in the East.

The 76ers are 0-4 ATS in their last 4 games following an ATS win and 1-3-1 ATS in the last 5 meetings with the Cavaliers. Cleveland is also 22-12-1 ATS at home this season.

Over/Under

LEAN OVER 219.5 (-115).

These teams play at snail-like paces, but this is a low total in a crucial bout. Despite both squads playing at a slow pace, they both are top 9 in offensive rating this season.

The 76ers are 6-2 to the Over in their last 8 games playing on 2 days of rest and the Cavaliers are 6-1 to the Over in their last 7 games following a win.

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Philadelphia 76ers at Cleveland Cavaliers odds, picks and predictions

Analyzing Wednesday’s Philadelphia 76ers at Cleveland Cavaliers odds and lines, with NBA expert picks, predictions and best bets.

The Philadelphia 76ers (12-9) take on the Cleveland Cavaliers (13-8) on Wednesday at the Rocket Mortgage FieldHouse. Tip-off is scheduled for 7 p.m. ET. Below, we analyze Tipico Sportsbook’s lines around the 76ers vs. Cavaliers odds, and make our expert NBA picks and predictions.

The 76ers defeated the Atlanta Hawks 104-101 on Monday as they covered as 2.5-point favorites at home. Philadelphia is currently on a 3-game winning streak and the team has won 7 of its last 10 games.

The Cavaliers suffered a 100-88 loss to the Toronto Raptors on Monday as they fell short of covering as 5-point underdogs. Cleveland has won 5 of its last 7 games.

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76ers at Cavaliers odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:24 a.m. ET.

  • Moneyline (ML): 76ers +140 (bet $100 to win $140) | Cavaliers -160 (bet $160 to win $100)
  • Against the spread (ATS): 76ers +3.5 (-110) | Cavaliers -3.5 (-110)
  • Over/Under (O/U): 211.5 (O: -110 | U: -110)

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76ers at Cavaliers key injuries

76ers

  • G James Harden (foot) out
  • G Tyrese Maxey (foot) out

Cavaliers

  • C Jarrett Allen (back) out
  • F Kevin Love (thumb) out

For most recent updates: Official NBA injury report.

76ers at Cavaliers picks and predictions

Prediction

Cavaliers 112, 76ers 106

Moneyline

Even though I envision seeing the Cavaliers winning at home on Wednesday, I’ll PASS on the moneyline in this game. This should be a close game, so it’s not worth the risk taking Cleveland straight up to secure a victory at the current odds.

Against the spread

While I won’t take Cleveland to win straight up, CAVALIERS -3.5 (-110) is an enticing wager in this game. While Allen won’t be available to guard C Joel Embiid, the Cavaliers should get a better performance out of G Donovan Mitchell after he scored only 8 points in Monday’s loss to the Raptors.

The Cavaliers are 9-1-1 ATS in their last 11 home games. Meanwhile, the 76ers are 2-5-1 ATS in their last 8 meetings with the Cavaliers.

Over/Under

OVER 211.5 (-110) appears to be too low of a number despite the injuries for both teams. Even though most of the trends point toward the Under being the ideal bet, the 76ers and the Cavaliers have hit Over 211.5 points in 3 straight meetings.

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Philadelphia 76ers at Cleveland Cavaliers odds, picks and prediction

Previewing Thursday’s Philadelphia 76ers at Cleveland Cavaliers NBA odds and lines, with basketball picks, tips and predictions.

The Philadelphia 76ers (32-15) visit the Cleveland Cavaliers (17-30) at Rocket Mortgage FieldHouse for a 7 p.m. ET tip-off. Below, we analyze the 76ers at Cavaliers odds and lines, with NBA picks and predictions.

The 76ers kicked off their six-game road trip with a 3-0 SU/2-0-1 ATS run with wins over the Knicks, Warriors and Lakers. They were dropped 122-112 against the Clippers, and they fell 104-95 to the Nuggets last time out Tuesday. The last time they faced the Cavaliers they were stunned 112-109 in overtime Feb. 27 at home as 11.5-point favorites.

The Cavaliers are back from a disastrous road trip. It started out OK, as they won 103-94 against the Bulls on March 24 as 7.5-point underdogs. But they finished up 0-3 SU/1-2 ATS with losses to the Lakers, Kings and Jazz, including an ugly 114-75 loss at Utah as they failed to cover a 16.5-point number.

76ers at Cavaliers: Odds, spread and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 7:30 a.m. ET.

  • Money line: 76ers -350 (bet $350 to win $100) | Cavaliers +290 (bet $100 to win $290)
  • Against the spread/ATS: 76ers -8.5 (-110) | Cavaliers +8.5 (-110)
  • Over/Under: 213.5 (O: -110 | U: -110)

76ers at Cavaliers: Key injuries

76ers

  • C Joel Embiid (knee) out

Cavaliers

  • C Jarrett Allen (concussion) out
  • PG Matthew Dellavedova (appendix) out
  • PF Kevin Love (calf) out
  • PF Larry Nance Jr. (illness) out
  • SF Dylan Windler (knee) doubtful

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76ers at Cavaliers: Odds, lines, predictions and picks

Prediction

76ers 116, Cavaliers 95

Money line (ML)

The 76ers (-350) will cost you three-and-a-half times your potential return, and that’s not a good investment. The Cavaliers (+290) have actually won each of the first two meetings this season. While Embiid is ruled out again, the 76ers should still have enough to push past the Cavs. But we’ve said that before and it hasn’t ended well.

AVOID.

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Against the spread (ATS)

The 76ERS -8.5 (-110) are a good bet laying just four buckets and a hook against the defensively challenged Cavaliers +8.5 (-110). Yes, Cleveland has won the first two meetings this season straight up as heavy underdogs. But they’re not playing very well lately, and it doesn’t help that they’ll be without Nance up front. Isaiah Hartenstein is likely to see considerable minutes. Who, you say? Exactly.

Over/Under (O/U)

The UNDER 213.5 (-110) is the way to go. The Under has cashed in five straight games for the Cavs, and the Under is 9-3 in their past 12 following a straight-up loss, too.

For the 76ers, the Under is on a 6-0 run across the past six as a road favorite, and 4-1 in the past five games overall. The Under is also 18-6 in the past 24 meetings in Cleveland between these two clubs.

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