Sweet 16 first look: Michigan vs. Villanova odds and lines

Looking at Thursday’s Michigan vs. Villanova NCAA Tournament Sweet 16 odds, lines and trends. Here’s what you need to know.

The No. 11-seed Michigan Wolverines (19-14) meet the No. 2 seed Villanova Wildcats (28-7) for a South Region Sweet 16 matchup Thursday. Tip-off from AT&T Center in San Antonio is scheduled for 7:29 p.m. ET. Below, we look at the Michigan vs. Villanova odds and lines; check back for our college basketball picks, predictions and bets.

Michigan has advanced in the tournament with wins over Colorado State (75-63 Thursday) and Tennessee (76-78 Saturday). The Wolverines had not won back-to-back games since early February prior to the bracket victories.

Michigan shot a combined 52% from the field while allowing a mere 38.6% figure across the wins over CSU and UT. The Wolverines also attempted 42 free throws in the two games despite that they got to the line just 14.6 times per game from Feb. 10-March 10.

Villanova — the fifth-ranked team in the nation — collected opening-week wins over Delaware (80-60 Friday) and Ohio State (71-61 Sunday) and, having previously swept three games in the Big East Tournament, heads into Thursday’s game on a seven-game win streak. The Wildcats have held opposing shooters to a 40.5% mark from the field and 26.6% figure on 3-pointers over those seven games.

Rankings courtesy of the Ferris Mowers Coaches Poll powered by USA TODAY Sports.

Michigan vs. Villanova odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 11:50 a.m. ET.

  • Money line: Michigan +175 (bet $100 to win $175) | Villanova -220 (bet $220 to win $100)
  • Against the spread (ATS): Michigan +4.5 (-103) | Villanova -4.5 (-117)
  • Over/Under (O/U): 134.5 (O: -115 | U: -105)

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2021-22 betting stats (including postseason):

  • ML: Michigan 19-14 |  Villanova 28-7
  • ATS: Michigan 15-18 |  Villanova 18-16-1
  • O/U: Michigan 21-12 |  Villanova 17-18

Michigan vs. Villanova head-to-head

The Wolverines and Wildcats have played each other three times over the last eight years. Villanova won two of those games, including the middle game of the three which was a national final April 2, 2018.

Since 2018, UM is 12-3 in the NCAA Tournament; Villanova is 11-2.

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