Straight-Up NFL Picks, Week 10: What to make of a maybe-slumping Buffalo Bills?

Are the Titans healthy enough to squash a Broncos revival? Are the Bills’ midseason slumps for real?

Last week’s predictions churned forward with an impressive success rate in a mostly boring week of football. Sure, we may not have seen Aaron Rodgers getting Mon-star’d in Detroit or Josh Allen getting outplayed by Zach Wilson (!), but Week 9 was, for the most part, a fairly standard affair.

Week 10 looks like more of the same, at least on paper. Only four of this week’s 14 games brought any kind of division among our three-man picking crew. It turns out we’re not sure on a possibly Malik Willis-led Tennessee Titans, whatever the Saints and Steelers are cooking up, and the midseason slumps of the Buffalo Bills and Los Angeles Rams.

Week 10 will provide a handful of proving ground moments for teams with Super Bowl aspirations. Can the Bills get right against a 7-1 Minnesota Vikings team? Do the Denver Broncos have enough offense to squeeze past Tennessee and keep their slim playoff hopes alive? Will the Green Bay Packers continue to collapse in upon themselves like a dying star?

Here’s our full lineup of straight-up moneyline picks for Week 10 of the 2022 NFL season.

Game Christian Robert Charles
Falcons at Panthers Falcons Falcons Falcons
Seahawks at Buccaneers Seahawks Seahawks Seahawks
Browns at Dolphins Dolphins Dolphins Dolphins
Broncos at Titans Titans Broncos Broncos
Lions at Bears Bears Bears Bears
Texans at Giants Giants Giants Giants
Jaguars at Chiefs Chiefs Chiefs Chiefs
Vikings at Bills Bills Vikings Bills
Saints at Steelers Steelers Steelers Saints
Colts at Raiders Raiders Raiders Raiders
Cardinals at Rams Rams Cardinals Rams
Cowboys at Packers Cowboys Cowboys Cowboys
Chargers at 49ers 49ers 49ers 49ers
Commanders at Eagles Eagles Eagles Eagles
Last week: 10-3 10-3 9-4
Year to date: 87-48-1 82-53-1 76-59-1

And here those pics are in a better-formatted screenshot of our actual picks sheet, which sadly struggles to translate to our editing software.

The * for the Titans depends on Ryan Tannehill starting, which it seems as though he will. Otherwise, I’m gonna have to take a long hard look at that game, which probably still leans toward the home team.