Stanford at Notre Dame odds, picks and predictions

Analyzing Saturday’s Stanford at Notre Dame odds and lines, with college football expert picks, predictions and best bets.

The Stanford Cardinal (1-4) and the Notre Dame Fighting Irish (3-2) meet at Notre Dame Stadium in South Bend, Ind. Kickoff is scheduled for 7:30 p.m. ET (NBC/Peacock). Below, we analyze Tipico Sportsbook‘s lines around the Stanford vs. Notre Dame odds, and make our expert college football picks and predictions.

The Cardinal suffered a heartbreaking loss against Oregon State last week, losing 28-27 on the final ticks on The Farm. On a positive note, it was Stanford’s first cover of the season in 5 tries, but it is now 0-4 SU in 4 games against FBS teams. The Over is also on a 4-0 run.

The Fighting Irish topped BYU in Las Vegas last week by a 28-20 count, picking up a 3rd consecutive victory, while covering the 2nd in a row. The Under has cashed in 4 of 5 games overall for the Irish.

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Stanford at Notre Dame odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:55 a.m. ET.

  • Moneyline (ML): Stanford +570 (bet $100 to win $570) | Notre Dame -850 (bet $850 to win $100)
  • Against the spread (ATS): Stanford +16.5 (-110) | Notre Dame -16.5 (-110)
  • Over/Under (O/U): 53.5 (O: -110 | U: -110)

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Stanford at Notre Dame picks and predictions

Prediction

Notre Dame 41, Stanford 27

Moneyline

Notre Dame (-850) will cost you 8 1/2 times your potential return, and that’s a ridiculous bet. Over the long term, betting with that kind of strategy is a losing proposition.

PASS.

Against the spread

STANFORD +16.5 (-110) doesn’t look terribly attractive since it is winless in 4 tries against FBS teams so far. However, this is the College Football Playoff for the Cardinal. This might even be their bowl game against their rival.

Stanford has shown a pretty decent ability to roll up points, going for 27 or more points in 4 of 5 games. Defense is where the Cardinal have struggled, and that will continue in the shadow of Touchdown Jesus Saturday.

Over/Under

OVER 53.5 (-110) is the best play on the board in this rivalry game.

The Over is 4-0 in the past 4 games for the Cardinal, while going 5-2 in the past 7 on the road, and 5-0 in the past 5 against winning teams. Not to mention, the Cardinal defense is an absolute sieve.

While it’s all about the Under for the Fighting Irish, it should have a tremendous offensive outburst in this one.

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