St. Louis Cardinals at Milwaukee Brewers odds, picks and predictions

Analyzing Wednesday’s St. Louis Cardinals at Milwaukee Brewers odds and lines, with MLB expert picks and predictions.

The St. Louis Cardinals (90-65) and Milwaukee Brewers (82-72) close out  a 2-game set Wednesday. First pitch is set for 7:40 p.m. ET at American Family Field. Let’s analyze Tipico Sportsbook‘s lines around the Cardinals vs. Brewers odds with MLB picks and predictions.

Season series: St. Louis leads 10-8

St. Louis won Tuesday’s game 6-2, but is just 3-5 in its last 8 games. The Redbirds own a .620 OPS over that stretch.

The Brewers are 4-2 in their last 6 games. Tuesday’s loss aside, Milwaukee’s offense has notched up a few clicks of late and the Brewers own a .760 OPS since Sept. 10.

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Cardinals at Brewers projected starters

LHP Jose Quintana vs. RHP Brandon Woodruff

Quintana (6-6, 3.03 ERA) is tabbed for his 31st start of the season. He has a 1.22 WHIP, 2.5 BB/9 and 7.4 K/9 in 157 2/3 IP.

  • Has a 1.91 ERA over his last 7 starts
  • Is up against a Milwaukee team that has had trouble against left-handers (.664 OPS)
  • Has logged 100-plus pitches in each of his last 2 starts
  • Owns a 4.13 ERA on the road and a 2.24 ERA at home

Woodruff (12-4, 3.18 ERA) has a 1.09 WHIP, 2.6 BB/9 and 11.0 K/9 through 141 1/3 IP across 25 starts.

  • Has allowed just 2 R in his last 14 IP and owns a 2.44 ERA over his last 7 starts
  • Has held current Cards batters to an aggregate .602 OPS
  • Owns a 1.35 ERA in his last 3 starts at home and a 2.16 home ERA for the season

Cardinals at Brewers odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:42 p.m. ET.

  • Money line: Cardinals +133 (bet $100 to win $133) | Brewers -165 (bet $165 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals +1.5 (-170) | Brewers -1.5 (+135)
  • Over/Under (O/U): 7.5 (O: +105 | U: -130)

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Cardinals at Brewers picks and predictions

Prediction

Brewers 5, Cardinals 4

Money line

Leaning into some possible Quintana fatigue in this spot. And backing Woodruff and his versus-batter and home-park splits.

Brewer bats have been more reliable of late.

TAKE MILWAUKEE (-165).

Run line/Against the spread

Skip the extra juice, and AVOID this play.

Over/Under

Mixed signals here, but a slight lean on the Over. Consider a partial-unit play on the OVER 7.5 (+105).

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