Seattle Mariners at Houston Astros odds, expert picks and prediction

Analyzing Wednesday’s Seattle Mariners at Houston Astros odds and lines, with MLB expert picks and predictions.

The Seattle Mariners (75-64) and Houston Astros (81-57) play the finale of a three-game series Wednesday at Minute Maid Park. First pitch is scheduled for 2:10 p.m. ET. Let’s analyze the lines around the Mariners vs. Astros odds with MLB picks and predictions.

Mariners LHP Tyler Anderson (6-9, 4.08 ERA) makes his 26th start. He has a 1.17 WHIP, 7.3 K/9 and 1.8 BB/9 through 143 1/3 IP.

  • Allowed three runs, four hits and a walk across 6 IP in a no-decision at Arizona on Friday.
  • Has posted a 1-1 record with a 3.38 ERA across seven starts across 40 IP since being acquired from the Pittsburgh Pirates in late July.

Astros RHP Jose Urquidy (6-3, 3.42 ERA) makes his 16th start. He has a 0.98 WHIP, 7.7 K/9 and 1.5 BB/9 through 81 2/3 IP.

  • Yielded just two runs, five hits and a walk in 4 1/3 IP in a no-decision at San Diego Friday, his first start since returning from a right shoulder injury.
  • Hasn’t lost in five starts with two victories and no losses dating back to June 5.

Mariners at Astros odds, lines, picks and prediction

MLB odds provided by Tipico Sportsbook; access USA TODAY Sports for a full list. Odds last updated at 7:40 a.m. ET.

  • Money line: Mariners +175 (bet $100 to win $175) | Astros -220 (bet $220 to win $100)
  • Against the spread/ATS: Mariners +1.5 (-115) | Astros -1.5 (-105)
  • Over/Under: 8.5 (O: -125 | U: +100)

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Prediction

Mariners 6, Astros 5

Money line (ML)

The MARINERS (+175) are worth a look as rather heavy underdogs in the series finale as they look to avoid the broom.

After getting blown out 11-2 in the opener Monday, they came up just short in 10 innings by a 5-4 count Tuesday. They have a good shot against Urquidy, who isn’t likely to go very deep into the game in just his second start since returning from a lengthy absence.

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Run line/Against the spread (ATS)

MARINERS +1.5 (-115) are a good play if you don’t quite trust Anderson and the visitors and want a little bit of insurance. This bet would have cashed Tuesday, even though Seattle lost.

Anderson has been decent since coming over from the Bucs, while Urquidy is likely to have a pitch limit before turning it over to the bullpen.

Over/Under (O/U)

OVER 8.5 (-125) is the play in the finale. The Over has connected in each of the first two games with an average of 11.0 total runs per game in the first two of the series. The Over is 8-3 in the past 11 meetings between these teams, and 5-for-5 in the past five meetings at Minute Maid Park.

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