The San Diego Padres (29-17) and San Francisco Giants (23-22) continue a four-game set at Petco Park Friday. First pitch of Game 2 is set for 9:10 p.m. ET. Below, we analyze the Giants-Padres MLB betting odds and lines, with picks and best bets.
Giants at Padres: Projected starting pitchers
RHP Johnny Cueto vs. RHP Garrett Richards
Cueto: 2-0, 9 starts, 4.56 ERA, 1.27 WHIP, 8.7 K/9, 3.6 BB/9, 47 1/3 IP
- Has allowed more than 2 earned runs in just three of nine starts this season and has completed at least 5 innings in 6 of his last 7 turns.
- Road ERA of 3.38 is markedly better than his 5.54 home rate.
Richards: 2-2, 9 starts, 4.50 ERA, 1.33 WHIP, 8.1 K/9, 3.0 BB/9, 42 IP
- Completed 7 innings for the second time this season in his last start when he held the Oakland Athletics to 3 earned runs with 9 strikeouts and no walks.
- Has an ugly 7.82 home ERA (11 ER, 12 2/3 IP) through 4 starts at Petco.
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Giants at Padres: Key injuries
(Get the latest injury news here.)
Giants
- OF Joey Rickard (elbow) out
Padres
- 1B Eric Hosmer (finger) out
- C Francisco Mejia (thumb) out
- OF Tommy Pham (hand) out
- RP Kirby Yates (elbow) out
Also see: BaseballHQ Fantasy Baseball
Giants at Padres: Odds, lines, picks and betting tips
MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 9:51 a.m. ET.
Prediction
Padres 7, Giants 3
Moneyline (ML)
Trust in Richards’ recent form rather than his poor home numbers this season and back the PADRES (-154) following their 6-1 win over the Giants (+140) Thursday.
The Padres rank second in MLB with a .851 team OPS against right-handed pitching, while the Giants are seventh at .775. San Diego also has a slight bullpen advantage (4.54 ERA) over San Francisco (4.63).
Run line/Against the spread (ATS)
The PADRES -1.5 (+125) have the best home run line record in baseball at 14-8, where they win by an average of 2 runs per game and cover the line by a full run. The Giants are 11-11 ATS on the road.
Over/Under (O/U)
Tap the OVER 9 (-110) while leaning on the powerful Padres lineup for the bulk of the scoring.
A three-game series between these two NL West rivals in late July played to totals of 8, 19 and 15 runs with the Padres winning two of three games by multiple runs.
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