The San Francisco Giants (23-21) and San Diego Padres (28-17) kick off a four-game set at Petco Park Thursday at 9:10 p.m. ET. We analyze the Giants-Padres MLB betting odds and lines, with picks and best bets.
Giants at Padres: Projected starting pitchers
RHP Trevor Cahill vs. RHP Chris Paddack
The veteran Cahill hasn’t factored into any decisions while posting a 2.65 ERA and 1.18 WHIP with 20 strikeouts over 17 innings through five starts.
- Cahill has worked 4 or fewer innings in four of his five appearances to date; however, the Giants are 4-0 across his past four starts.
- Cahill’s longest outing was Aug. 23, allowing just one earned run, one hit and two walks with eight strikeouts over 5 1/3 innings in a no-decision against the Arizona Diamondbacks.
Also see: BaseballHQ Fantasy Baseball
Paddack has managed a 3-4 record, 4.75 ERA and 1.25 WHIP with 48 strikeouts across 47 1/3 innings in his nine starts.
- Paddack allowed two earned runs, six hits and no walks with six strikeouts across five innings in a no-decision at AT&T Park in San Francisco in his second start of the season.
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Giants at Padres: Key injuries
(List of injuries around the league)
Padres
- 1B Eric Hosmer (finger) out
- OF Tommy Pham (hand) out
- RP Kirby Yates (elbow) out
Giants at Padres: Odds, lines, picks and betting tips
MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 11:45 a.m. ET.
Prediction
Giants 5, Padres 4
Moneyline (ML)
The Padres (-189) are the overwhelming favorites for this series opener. Both of these teams are red hot, as San Diego has won four in a row, and San Francisco (+170) has picked up five consecutive victories to move two games over .500 and into the thick of the postseason race. The GIANTS (+170) are the better value here, as they are 5-1 in their past six showings at Petco Park.
New to sports betting? A winning $10 bet on San Francisco returns a profit of $17, while a $10 wager on San Francisco nets a profit of $5.30 if it wins.
Run line/Against the spread (ATS)
If you’re not feeling the GIANTS (+1.5, -125) on the road straight up, they’re rather affordable on the run line. Even if they lose by one run you still win.
Over/Under (O/U)
O/U 9 (-110) is the line for this one, and I feel it’s going to be right on the number. San Francisco is averaging 5.6 runs per game during its five-game win streak, allowing 3.0 runs per outing. The Padres have racked up 6.3 runs per game during their four-game win streak, yielding 3.0 runs per contest.
PASS.
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