Prediction and betting odds for 49ers vs. Bears in Week 14

Analyzing Sunday’s 49ers vs. Bears game with odds and lines, predictions and best bets.

The San Francisco 49ers (5-7) are running out of real estate to make a run at an NFC West title and a return to the playoffs.

The 49ers welcome in the reeling Chicago Bears (4-8) to Levi’s Stadium for a Sunday afternoon date. Led by rookie quarterback and recent No. 1 overall draft pick Caleb Williams, Chicago has lost six straight as it went spiraling out of the playoff picture.

Of those six straight losses, four have been one-score defeats. The Chicago Bears’ embarrassing clock mismanagement to end its Thanksgiving Day loss at Detroit cost head coach Matt Eberflus his job.

As San Francisco looks to snap its own three-game losing streak, here’s a look at the latest odds, including the spread, over-under and a prediction for the game.

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49ers vs. Bears game odds:

All College Football Odds via BetMGM:

  • Point spread: 49ers -3
  • Money line: 49ers -175 / Bears +145
  • Over-under: 43.5

49ers vs. Bears injury updates:

  • San Francisco LB Dre Greenlaw – OUT (Achilles)
  • San Francisco S George Odum – OUT (knee)
  • San Francisco RB Jordan Mason – OUT (ankle)
  • San Francisco LT Trent Williams – OUT (ankle)
  • San Francisco DE Nick Bosa – Doubtful (hip, oblique)
  • San Francisco LG Aaron Banks – Questionable (concussion)
  • Chicago OL Ryan Bates – OUT (concussion)
  • Chicago DB Elijah Hicks – OUT (ankle)
  • Chicago RB Roschon Johnson – OUT (concussion)
  • Chicago WR DJ Moore – Questionable (quad)
  • Chicago RB D’Andre Swift – Questionable (quad)

49ers vs. Bears prediction, pick

Prediction: San Francisco 23, Chicago 17

The 49ers have to get this game if there’s any hope of an NFC West title and a return to the playoffs.

Despite at least one key missing piece on the left side of its offensive line, 49ers head coach Kyle Shanahan dials up enough offense with Brock Purdy and Co. at home to pick up win No. 6 on the season and keep San Francisco in the mix.

It’s another one-score loss for the Bears.

49ers vs. Bears channel, start time, streaming:

The 49ers vs. Bears game starts at 1:25 p.m. PT and can be seen on Fox.

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Get more betting analysis and predictions at Sportsbook Wire.