The contest took place at Doug Kingsmore Stadium in Clemson, South Carolina.
The Vols lead the all-time series versus Charlotte, 5-2.
Tennessee is making its fourth consecutive NCAA Tournament appearance under head coach Tony Vitello.
Tennessee will next play Clemson on Saturday at 6 p.m. EDT.
No. 1 seed Clemson is the host school for the regional. The Tigers defeated Lipscomb, 12-5, on Friday.
2023 NCAA Tournament Clemson Regional baseball schedule
PHOTOS: A look at Tony Vitello through the years
Below are photos of Tennessee’s NCAA Tournament Clemson Regional win versus Charlotte on Friday.