Philadelphia Eagles at Detroit Lions odds, picks and predictions

The Philadelphia Eagles take on the Detroit Lions to open up each team’s 2022 season. Kickoff is 1 p.m. ET (FOX). Below, we analyze Tipico Sportsbook‘s lines around the Eagles vs. Lions odds, and make our expert NFL picks and predictions.

The Eagles enter the season with high hopes for QB Jalen Hurts. The dual-threat quarterback lost WR Jalen Reagor in a trade to the Minnesota Vikings, but picked up WR A.J. Brown in a trade with the Tennessee Titans. Week 1 will be the opening test to see if Hurts and Brown have the desired chemistry that the front office expected when making the moves.

On defense, the Eagles will hope to stop the run with 1st-round pick DE Jordan Davis. Alongside CB Darius Slay, the Eagles expect the addition of CB James Bradberry will help prevent opposing offenses from gaining big yards through the air.

For the Lions, all eyes will be on the 1st pick of the NFL Draft — DE Aidan Hutchinson, who is being counted on to improve a defense that allowed 110 rushing yards per game in 2021.

On the offensive side of the ball, the team and coach Dan Campbell have complete faith in QB Jared Goff. Watch for Goff to target his top WRs Amon-Ra St. Brown and D.J. Chark.

The stars of the 2022 HBO series “Hard Knocks” will hope for an improved season after finishing 3-13-1 last season, 2nd-worst in the league.

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Eagles at Lions odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:36 a.m. ET.

Money line (ML): Eagles -230 (bet $230 to win $100) | Lions +190 (bet $100 to win $190)
Against the spread (ATS): Eagles -5.5 (-108) | Lions +5.5 (-112)
Over/Under (O/U): 48.5 (O: -108 | U: -112)

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Eagles at Lions key injuries

Eagles

None

Lions

OG Tommy Kraemer (back) out
C Frank Ragnow (groin) questionable

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Eagles at Lions picks and predictions

Prediction

Eagles 31, Lions 20

Money line

PASS.

The value is not there for the return on investment.

Against the spread

BET EAGLES -5.5 (-108).

The Eagles are a strong contender for the NFC East title. They look to start the season off with a big win against a team that is coming off a brutal season.

Philadelphia is led by a dual-threat quarterback who is primed for a huge season, and it is tough to envision Detroit being ready for his speed.

The Lions have made improvements, but it will not be enough to stay within a touchdown in this game. Detroit is still a few years away from being true playoff contenders.

The Eagles are 5-2-1 in their last 8 games ATS as a favorite.

Over/Under

LEAN OVER 48.5 (-108).

Hurts and the rest of the Eagles offense should be firing on all cylinders Sunday. They had an impressive offseason and will hope to prove why they are potential Super Bowl contenders.

In the last 8 meetings between these teams the over is 8-0 and in the last 4 meetings in Detroit the over is 4-0.

Expect an offensive-heavy game, especially with the Eagles likely looking to pick up the tempo to start the season.

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