NFL Week 16 picks: Who the experts are taking in Rams-49ers

Not many experts are picking the Rams to beat the 49ers on Saturday night.

There’s only one path to the postseason for the Rams – and while it’s very clear, it’s also highly unlikely to happen. They need to win out and the Vikings need to lose their last two games, which begins with the Rams beating the 49ers on Saturday night.

It’s a difficult matchup against a team that they lost to 20-7 already this season, and the Rams enter as 6.5-point underdogs. The oddsmakers don’t expect them to win, and neither do many experts.

According to NFL Pick Watch, only 4% of experts are taking the Rams to win straight-up on Saturday with a whopping 96% taking San Francisco. Only the Browns (1%), Jaguars (1%), Lions (1%), Cardinals (0%) and Bears (0%) have a lower contingent of experts picking them.

The Rams have not lost to the same team twice in a season since Sean McVay took over in 2017, so that’s something they’ll try to avoid this weekend. San Francisco is coming off a loss to the Falcons in Week 15, but with a dominant ground attack and stout defense, the 49ers certainly pose a major threat to the Rams.