NFL picks against the spread: Week 16 Saturday games

There are three games on the schedule on Saturday, Here are our picks.

The NFL kicks off Week 16 with three games on Saturday. it begins with the Houston Texans facing the Tampa Bay Buccaneers, followed by a couple of divisional battles with the Bills and Patriots and then the Rams and 49ers.

It is time to make our picks against the spread for these games. All odds come from BetMGM.

Texans (-3.5) at Buccaneers

Jason Getz-USA TODAY Sports

ATS pick: Texans -3.5

Over/under: OVER 50.5

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