NFL Parlay Payday: Top Week 12 parlay bet predictions

Highlighting five NFL betting predictions and best bets to combine into one 5-leg parlay for Week 12.

Week 12 of the NFL season is already underway with two games being played on Thanksgiving. To get you excited for the upcoming games, we will be creating a 5-bet NFL parlay with several money line underdogs. Let’s take a look at our top Week 12 NFL parlay.

NFL Week 12 parlay picks and predictions

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Friday at 12:25 p.m. ET.

Leg 1: Arizona Cardinals at New England Patriots (+105)

Arizona traveling to the east coast to play a 1 p.m. ET game against head coach Bill Belichick? That smells like an upset to me. New England is getting All-Pro CB Stephon Gillmore back in the lineup and he should help slow down Cardinals WR DeAndre Hopkins. I expect this game to be close, but for the Patriots to find a way to win at home.

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Leg 2: Tennessee Titans (+155) at Indianapolis Colts

With Colts DT DeForest Buckner out Sunday due to a positive COVID-19 test, the Indianapolis defense doesn’t look all that scary. Titans RB Derrick Henry should have no problem running through this defense as late-November is when he starts to heat up. At +155, these odds are just too good to pass up for a good Titans team.

Also see: Titans at Colts odds, picks and prediction

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Leg 3: Los Angeles Chargers (+200) over Buffalo Bills

The Chargers are one of the league’s most talented teams, but they often have trouble closing out games. Can they do it this week against a Bills team coming off a bye? QB Justin Herbert is just too talented of a quarterback to be a 2-1 money line underdog in this game and for the value, we are riding with the Chargers.

Leg 4: Kansas City Chiefs -3 (-115) at Tampa Bay Buccaneers

Anytime you can bet on QB Patrick Mahomes to cover a field-goal spread, you have to take it. Tampa Bay is coming off a rough loss on Monday Night Football and its secondary got exposed in that game. The Bucs will be taking on an even bigger challenge this week as the Chiefs have one of the best offenses in NFL history. Take KC to win by 4 or more points and don’t look back.

Special NFL Betting Promotion

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New customer offer, terms and conditions apply. Bet now!

Leg 5: Seattle Seahawks -5 (-110) at Philadelphia Eagles

The final leg of our parlay happens on Monday Night Football. The Seahawks are just 5-point favorites over a team that looks completely out of sorts. Look for the Seahawks to put up a bunch of points in this game and cover this spread with ease.

5-TEAM PARLAY | Bet $100 to earn a profit of $5,597.35

Want action on these NFL games? Sign up and bet at BetMGM. If you’re looking for more sports betting picks and tips, visit SportsbookWire.com. Please gamble responsibly.

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