New York Giants at Dallas Cowboys odds, picks and predictions

Analyzing Sunday’s New York Giants at Dallas Cowboys odds and lines, with expert NFL picks and predictions.

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The Dallas Cowboys (4-7) host the New York Giants (2-9) on Thursday during the Cowboys’ annual Thanksgiving Day home game. Kickoff from AT&T Stadium is scheduled for 4:30 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Cowboys vs. Giants odds, and make our expert NFL picks and predictions.

This Texas holiday hoedown marks the second meeting of the year between these 2 impending postseason spectators. The Cowboys survived the first matchup, an ugly 20-15 win in Week 4 on Thursday Night Football.

Dallas surprised the Washington Commanders with a wild 34-26 win Sunday. New York failed to generate much offense during its 30-7 loss on the same day to the Tampa Bay Buccaneers.

Neither club will feature its preseason starting QB. The Cowboys have been without Dak Prescott (hamstring) since Week 9; he’s on IR and out for the season. Meanwhile, the Giants benched and then released Daniel Jones before their previous game.

With a surprising 2-game stretch that included upending the Commanders, QB Cooper Rush will carry the flag for the home team. The Giants likely won’t have cutlets at the feast, though: QB Tommy DeVito (right forearm) is likely to be replaced by Drew Lock.

Still, it’s football on Thanksgiving, so you know we’re betting on it.

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Giants at Cowboys odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Wednesday at 3:43 p.m. ET.

  • Moneyline (ML): Giants +150 (bet $100 to win $150) | Cowboys -185 (bet $185 to win $100)
  • Against the spread (ATS): Giants +3.5 (-115) | Cowboys -3.5 (-105)
  • Over/Under (O/U): 37.5 (O: -110 | U: -110)

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Giants at Cowboys key injuries

Giants

  • QB Tommy DeVito (forearm) questionable

Cowboys

  • CB DaRon Bland (foot)
  • WR Brandin Cooks (knee)
  • CB Trevon Diggs (groin/knee)
  • TE Jake Ferguson (concussion)
  • LB Eric Kendricks (groin/shoulder)
  • WR CeeDee Lamb (back/foot)
  • G Zack Martin (ankle/shoulder)
  • QB Cooper Rush (knee)
  • G Tyler Smith (ankle/knee)

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Giants at Cowboys picks and predictions

Prediction

Cowboys 21, Giants 20

Moneyline

After the announcement that Lock likely would replace DeVito, the odds swung in the Giants’ favor toward a less-profitable (+150) from (+165).

Despite the ample flaws in his game, Lock boasts a deep ball that should keep the Giants in the game if they fall behind.

Either way, rookie RB Tyrone Tracy looks primed to feast on the Cowboys’ defensive interior and give Lock room to work.

One or two plays could swing the entire outcome of this matchup, especially with Lock taking over. Dallas was -200 before that news swung things violently.

Neither side has enough +EV for bettors to care about the ML, unless it’s in a parlay. Find other avenues for betting this game.

PASS.

Against the spread

Both clubs struggle ATS (Cowboys 3-7-1, Giants 2-8-1).

Although the Giants’ juice was a bit friendlier at (-105) earlier in the week, take the points, especially with a more experienced quarterback under center to take better advantage of New York’s intriguing offensive pieces.

BET GIANTS +3.5 (-115).

Over/Under

Rush exceeded expectations during Dallas’ win over Washington. The backup-turned-starter continued the Cowboys’ success on the Over/Under, pushing them to 7-4 on the year.

The Giants’ offense has hardly reached those heights at 3-8 against the total.

Still, Dallas’ defense should provide enough help to let the Giants hold up their end of the bargain, especially if New York can simply get the ball in star rookie WR Malik Nabers‘ hands in space.

Luckily, the total dipped from 38.5 on Monday to 37.5 at time of writing, which justifies backing the Over even more strongly as the strongest wager of these 3 categories.

BET OVER 37.5 (-110).

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