New York Giants at Dallas Cowboys odds, picks and predictions

The New York Giants (7-3) take their show on the road to face the Dallas Cowboys (7-3) for the late-afternoon Thanksgiving Day game. Kickoff at AT&T Stadium is at 4:30 p.m. ET (FOX). Below, we analyze Tipico Sportsbook‘s lines around the Giants at Cowboys odds, and make our expert NFL picks and predictions.

The Giants are dealing with injury questions all along the offensive line and with both starting cornerbacks. The Giants may have to call up multiple players from the practice squad to fill in offensive line depth because 3 starters have been ruled out and another is questionable.

Illness has also struck the Cowboys offense and almost their entire defensive line is either doubtful or questionable, which could make this like a preseason game in the trenches.

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Giants at Cowboys odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Wednesday at 11:07 p.m. ET.

Moneyline (ML): Giants +380 (bet $100 to win $3860) | Cowboys -475 (bet $475 to win $100)
Against the spread (ATS): Giants +10 (-111) | Cowboys -10 (-109)
Over/Under (O/U): 45 (O: -113 | U: -107)

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Giants at Cowboys key injuries

Giants

TE Daniel Bellinger (eye) out
C Jon Feliciano (neck) out
CB Adoree Jackson (knee) out
G Shane Lemieux (toe) out
CB Fabian Moreau (oblique) out
OT Evan Neal (knee) out
OT Andrew Thomas (illness) questionable

Cowboys

LB Anthony Barr (hamstring) out
DE Tarell Basham (illness) questionable
DE Dante Fowler (illness) questionable
DT Jonathan Hankins (illness) doubtful
DE DeMarcus Lawrence (foot) questionable
DT Osa Odighizuwa (knee) questionable
LB Micah Parsons (knee/ankle) questionable

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Giants at Cowboys picks and predictions

Prediction

Cowboys 31, Giants 16

Moneyline

PASS.

The Cowboys are prohibitive favorites so the moneyline investment is far too steep for the return that you would get, so avoiding this bet is a must.

Against the spread

COWBOYS -10 (-109).

I hate this point spread because the Giants could be 3 scores down and score a late meaningless TD and either cover or push this bet.

That said, the last 5 wins by the Cowboys have come by more than 10 points, the last 2 Giants losses have been by double-digits and the Cowboys have won 4 of the last 6 head-to-head meetings by more than 10 points.

The Giants are a team built to play from ahead or in a close game. If Dallas gets a double-digit lead, it will be very difficult for the Giants to pass their way back into the game. Once the Giants get down by 10 (if they do), the game will be over.

Given the gaping holes in the offensive line, if there’s going to be a blowout, it will be by the Cowboys and the final injury report was troubling for Giants fans (and bettors) to say the least.

Over/Under

LEAN OVER 45 (-113)

The Cowboys beat the Giants 23-16 without Dak Prescott in Week 3 and the Dallas offense is clicking in both the pass and run game now. Dallas is capable of putting up 30 or more points, which doesn’t leave the Giants required to do that much.

I believe Saquon Barkley and the run game can get New York in scoring position enough to make the Over reachable. It may not come until very late, but the Cowboys have shown a penchant for not taking their foot off the gas if they get a big lead, so the Over can be achieved under a couple very different scenarios.

The big question here will be if the injuries on the Giants O-line will prevent them from getting close to the goal line. It’s definitely a possibility, so this is more of a “leaning to” bet projection than a rock solid pick.

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