The New York Giants (1-3) and Dallas Cowboys (3-1) will participate in a classic NFC East divisional battle Sunday of Week 5. Kickoff is at 4:25 p.m. ET at AT&T Stadium. Below, we look at the Giants vs. Cowboys odds and lines, and make our best NFL picks, predictions and bets.
The Giants picked up their first win in Week 4 after three losses to the start the season, knocking off the New Orleans Saints 27-21 in overtime. QB Daniel Jones passed for 402 yards and 2 touchdowns, earning him NFC Offensive Player of the Week honors.
The Cowboys have won three straight games and are undefeated (2-0) at home. QB Dak Prescott threw 4 touchdown passes and RB Ezekiel Elliott rushed for 143 yards and a score in a 36-28 win over the previously unbeaten Carolina Panthers in Week 4.
Giants at Cowboys odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 10:40 a.m. ET.
- Money line: Giants +230 (bet $100 to win $230) | Cowboys -300 (bet $300 to win $100)
- Against the spread (ATS): Giants +6.5 (-102) | Cowboys -6.5 (-122)
- Over/Under (O/U): 52.5 (O: -110 | U: -110)
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Giants at Cowboys key injuries
Giants
- WR Sterling Shepard (hamstring) out
- WR Darius Slayton (hamstring)
- OT Andrew Thomas (foot) questionable
- DB Jabril Peppers (hamstring) out
- OL Ben Bredeson (hand) out
Cowboys
- RB Ezekiel Elliott (knee) questionable
- DE Randy Gregory (knee) questionable
- DE Dorance Armstrong (ankle) out
- WR Amari Cooper (hamstring) questionable
- OT Ty Nsekhe (illness) questionable
- DE Carlos Watkins (knee) questionable
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Giants at Cowboys odds, lines, predictions and picks
Prediction
Cowboys 34, Giants 24
Money line
The Giants defeated the Cowboys in Week 17 last season but Dallas has dominated the series in recent history. The Cowboys had won the previous seven matchups.
Dallas scored at least 29 points in three of four games. New York has been uneven offensively with 14 or fewer points twice and 27 or more twice.
So far, only the Los Angeles Chargers showed any ability to slow the Cowboys.
Take the COWBOYS (-300).
Against the spread
The Cowboys are the only team in the NFL to have covered the spread in every game this season. The Giants are 2-2 ATS.
In the Cowboys’ seven-game winning streak against the Giants, they won by 7 or more points five times.
Take the COWBOYS -6.5 (-122).
Over/Under
Three of the Cowboys’ four games this season hit the Over. The Giants are 2-2 O/U.
This will be a tough game to get Over the projected total, as it is in the 50s but because the Cowboys are 31st in passing defense, Jones will be able to keep the Giants offense somewhat on pace with the vaunted Dallas offense, although this will be a game the Cowboys control.
Take OVER 52.5 (-110).
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