New Orleans Saints at Detroit Lions odds, picks and best bets

Previewing the New Orleans Saints at Detroit Lions Week 4 betting odds, spread and lines, with NFL betting picks, tips and best bets.

Coming off their first win of the season, the Detroit Lions (1-2) host the New Orleans Saints (1-2) Sunday at 1 p.m. ET at Ford Field. Below, we analyze the Saints-Lions Week 4 matchup, including the betting odds, spread and lines, and look at the best NFL betting options.

Saints at Lions betting odds and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Friday at 5:05 am. ET.

  • Money line: Lions +180 (bet $100, win $180) | Saints -213 (Bet $213, win $100)
  • Against the spread/ATS: Lions +4 (-110) | Saints -4 (-110)
  • Over/Under: 54.5 (O: -110, U: -110)

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Saints at Lions game notes

  • Detroit picked up its first win of the season in Week 3, a 26-23 last-second road win over the Arizona Cardinals.
  • The Saints are allowing opponents to convert on third down 49% of the time. The Lions convert on third down 40% of the time.
  • Detroit has had leads in every game this season.
  • The Saints have allowed more than 30 points in each of their last two games.
  • Saints WR Michael Thomas should return this week.

Saints at Lions key injuries

Saints

  • G Andrus Peat (ankle) doubtful
  • TE Jared Cook (groin) out
  • CB Janoris Jenkins (illness, shoulder) limited Thursday
  • DE Marcus Davenport (elbow, toe) DNP Thursday
  • CB Marshon Lattimore (hamstring) doubtful
  • WR Michael Thomas (ankle) limited Thursday

Lions

  • CB Desmond Trufant (hamstring) questionable
  • CB Darryl Roberts (hip) questionable

Saints at Lions: Odds, betting lines, picks and prediction

Prediction

Saints 35, Lions 30

Money line (?)

The Saints enter the game favored and have lost two in a row, allowing more than 30 points in each game. The Lions are coming off a win. With Thomas’ return at receiver for New Orleans, its offense should look more like it has in the past, but its defense will struggle to defend the Lions passing game. However, Detroit’s defense is not good and, unless it gets three takeaways like in Arizona, the Lions have little chance to slow the Saints. Take the SAINTS -213.

New to sports betting? Every $213 wagered on the Saints to win outright will return a profit of $100 if they prevail.

Against the Spread (?)

Both teams are 1-2 ATS so far this season. With Thomas’ return to the Saints lineup, they should be able to put up points. Four points isn’t giving up much, so with a late score, they will cover the spread. Take the SAINTS -4 (-110).

Over/Under (?)

New Orleans’ games have gone Over in all three games. Detroit’s have hit the Over in two of three. These are two talented quarterbacks with all their offensive weapons, while both defenses have struggled. This is a lock. Take the OVER 54.5 (-110).

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