New Orleans Saints at Carolina Panthers odds, picks and predictions

Analyzing Monday’s New Orleans Saints at Carolina Panthers odds and lines, with expert NFL picks and predictions.

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The New Orleans Saints (1-0) and the Carolina Panthers (0-1) meet Monday night at Bank of America Stadium in Charlotte, N.C. Kickoff is scheduled for 7:15 p.m. ET (ESPN/ESPN2). Below, we analyze BetMGM Sportsbook’s lines around the Saints vs. Panthers odds, and make our expert NFL picks and predictions.

The Saints opened with a 16-15 victory over the Tennessee Titans in Week 1, as QB Derek Carr made his team debut with 305 passing yards, 1 TD and 1 INT. New Orleans had 351 total yards of offense, and it was a plus-1 in turnover ratio.

The Panthers suffered a 24-10 setback on the road against the Atlanta Falcons in Week 1, as QB Bryce Young struggled in his NFL debut. He completed 20-of-38 passes for 146 yards, 1 TD and 2 INT. The good news is that Carolina had 20 first downs to just 13 for Atlanta, while outgaining the Falcons by a 281-to-221 margin.

Carolina has won 3 of the past 4 meetings, while also going 3-1 against the spread (ATS) in that span. The Panthers have won the past 2 meetings at home, with the Saints last winning at BoA on Jan. 3, 2021 by a 33-7 score. The Under has cashed in each of the past 5 meetings.

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Saints at Panthers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 4:38 a.m. ET.

  • Moneyline (ML): Saints -165 (bet $165 to win $100) | Panthers +140 (bet $100 to win $140)
  • Against the spread (ATS): Saints -3 (-110) | Panthers +3 (-110)
  • Over/Under (O/U): 39.5 (O: -110 | U: -110)

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Saints at Panthers key injuries

Saints

  • DB Juantavius Gray (shoulder) questionable
  • RB Kendre Miller (hamstring) questionable

Panthers

  • WR DJ Chark Jr. (hamstring) questionable

Saints at Panthers picks and predictions

Prediction

Panthers 20, Saints 18

Moneyline

The PANTHERS (+140) are a solid value at home as slight ‘dogs.

Carolina’s pass game wasn’t great in the opener in Atlanta, but there will be growing pains with Young. However, there will also be glimpses of brilliance, too. And it wasn’t all bad in Atlanta, as the Panthers outgained the Falcons, and RB Miles Sanders was solid in his team debut. The defense also did a good job of putting the team in position to win, and it will do well against Carr and the Saints pass offense, which was just OK in the opener.

Against the spread

The PANTHERS +3 (-110) are an OK play if you just can’t pick them straight up. However, there isn’t a lot of wiggle room, unless you strongly believe the Saints -3 (-110) are going to win, but only by 1 or 2 points. The better value is the moneyline play.

Over/Under

UNDER 39.5 (-110) is the lean in this Monday night undercard.

The Under cashed in Week 1 for the Saints, and the Under also cashed in Week 1 for the Falcons. If you’re seeing a theme here, you should. The Under has also cashed in each of the previous 5 meetings between these NFC South combatants.

The Under is also 7-3 in the past 10 games inside the NFC South Division for the Panthers, while cashing in each of the past 5 games inside the division for the Saints. The Under is 7-2 in the past 9 games against division foes for New Orleans, too.

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