Minnesota Vikings at New Orleans Saints odds, picks and prediction

Previewing the Minnesota Vikings at New Orleans Saints Week 16 betting odds and lines, with NFL betting picks, tips and predictions.

The Minnesota Vikings (6-8) have ended the season for the New Orleans Saints (10-4) in two of the last three seasons and look to ruin the Saints Christmas as they invade the Mercedes-Benz Superdome at 4:30 p.m. ET Friday. Below, we preview the Vikings-Saints betting odds and lines and make our NFL picks and predictions.

See also: Prop Bet Payday: Bank on these Vikings props for Week 16

Vikings at Saints: Betting odds, spread and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Thursday at 4:55 p.m. ET.

  • Money line: Vikings +240 (bet $100 to win $240) | Saints -300 (bet $300 to win $100)
  • Against the spread/ATS: Vikings +7 (-115) | Saints -7 (-105)
  • Over/Under: 50.5 (O: -110 | U: -110)

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Vikings at Saints: Game notes

  • Minnesota is 0-5 ATS in its last five games.
  • New Orleans is 4-1 straight up in its last five home games.
  • Minnesota has hit the Over in six of its last nine games, while the Saints have hit the Under in five of its last seven games.
  • The Saints are 9-2 ATS in their last 11 games versus teams with losing records.
  • New Orleans has won four of the last five regular-season meetings, but Minnesota has won the last meeting in the postseason, which nobody in New Orleans can forget.

Vikings at Saints: Key injuries

Vikings

  • LB Todd Davis (ribs) doubtful
  • LB Eric Kendricks (calf) out
  • FB C.J. Ham (quadriceps) questionable
  • DE Jalyn Holmes (groin) out
  • TE Kyle Rudolph (foot) out

Saints

  • G Nick Easton (concussion) out
  • Andrus Peat (ankle) questionable
  • WR Tre’Quan Smith (ankle) out
  • S Marcus Williams (ankle) out

Vikings at Saints: Odds, betting lines, predictions and picks

Prediction

Saints 34, Vikings 20

Money line (?)

The Saints are a prohibitive favorite at -300 and they should win this game handily against a banged-up Minnesota defense. However, given Minnesota’s unlikely wins over the Saints in the past, it isn’t a lock that New Orleans will blow out the Vikings because the Saints’ defense gives up too many big plays and Minnesota has the weapons to do damage. AVOID this bet.

Against the spread (?)

The Saints are favored by seven points primarily because Minnesota’s defense is so vastly different as it was just a year ago because of free-agent losses and injuries at too many key positions.  QB Drew Brees didn’t look sharp in his return from injury last week but should be able to pick apart Minnesota’s suspect defense. TAKE THE SAINTS and lay the seven points at -105.

Over/Under (?)

This is the toughest of the three bets because the 50.5-point total is a high number, but both offenses have the firepower to get in a back-and-forth battle and defenses that are capable of giving up big scoring days. Minnesota’s defense is worse, so Brees & Co. should be in for a prolific day. TAKE THE OVER at -110.

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