Milwaukee Brewers at St. Louis Cardinals odds, picks and predictions

Analyzing Friday’s Milwaukee Brewers at St. Louis Cardinals odds and lines, with MLB expert picks and predictions.

The Milwaukee Brewers (29-16) meet the St. Louis Cardinals (24-20) for the 2nd of their 4-game set at Busch Stadium. First pitch is scheduled 8:15 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Brewers vs. Cardinals odds with MLB picks and predictions.

The Brewers held off the Cardinals for a 4-3 victory in the series opener to take a 3-2 lead in the season series, but St. Louis has a plus-4 run differential in those meetings.

Milwaukee is on a 3-game winning streak and 7-3 in the last 10 games while St. Louis has lost back-to-back games and is 5-5 in its last 10.

Brewers at Cardinals projected starters

RHP Brandon Woodruff vs. RHP Dakota Hudson

Woodruff is 5-2 with a 4.76 ERA, 1.29 WHIP, 2.7 BB/9 and 11.1 K/9 in 39 2/3 IP over 8 starts.

  • Last start: Won 5-1 Saturday at home vs. the Washington Nationals with 6 IP, 1 ER, 5 H, 1 HR, 0 BB and 6 K.
  • 2022 vs. the Cardinals: Pitched 5 scoreless innings, 3 H, 1 BB and 2 K in 5-1 home win April 14.

Hudson is 3-2 with a 3.60 ERA, 1.35 WHIP, 4.3 BB/9 and 5.0 K/9 in 40 IP across 8 starts.

  • Last start: No-decision in St. Louis’s 7-6 loss May 19 at the New York Mets with 4 2/3 IP, 4 ER, 5 H, 2 BB and 2 K.
  • 2022 vs. the Brewers: One start, a 6-5 loss in Milwaukee April 17  with 3 IP, 3 ER, 3 H, 2 BB and 2 K.

Brewers at Cardinals odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:18 p.m. ET.

  • Money line (ML): Brewers -140 (bet $140 to win $100) | Cardinals +115 (bet $100 to win $115)
  • Run line (RL)/Against the spread (ATS): Brewers -1.5 (+122) | Cardinals +1.5 (-150)
  • Over/Under (O/U): 7.5 (O: +105 | U: -130)

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Brewers at Cardinals picks and predictions

Prediction

Cardinals 5, Brewers 3

Money line

LEAN CARDINALS (+115) only because the Brewers (-140) have the better bullpen and Woodruff was an All-Star last season who has yet to find his groove in 2022. Woodruff’s basic and advanced pitching numbers vs. St. Louis are much better than Hudson’s against Milwaukee.

But, sharp action has dragged the Cardinals from a +130 underdog on the opener down to the current number, according to Pregame.com. This is due to there not being a big difference between these ball clubs, Woodruff struggling on the road and Hudson pitching much better at home.

Woodruff is 1-2 on the road (4-0 at home) with a 9.00 ERA (1.59 home ERA) and 2.06 WHIP (0.71 home WHIP). Hudson is 2-0 at home (1-2 on the road) with a 1.80 ERA (4.68 road ERA) and 1.07 WHIP (1.52 road WHIP).

BET a half-unit on the CARDINALS (+115) since this is a toss-up game but the home team has a slight edge.

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Run line/Against the spread

PASS because the Cardinals +1.5 (-150) are just 3-4 RL as home underdogs and the last 3 Brewers-Cardinals meetings have been decided by a single run.

Over/Under

PASS because the trends are all over the place.

Brewers-Cardinals is 2-5 O/U in their last 7 meetings and Milwaukee is 0-6 O/U in the last 6 games vs. teams with a winning record.

However, these teams have a combined 10-6 O/U record when these starters get the nod, the Brewers are 8-7-2 O/U as road favorites, and the Cardinals are 5-2 O/U as home underdogs.

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