Michigan State at Notre Dame odds, picks and predictions

Analyzing Wednesday’s Michigan State at Notre Dame odds and lines, with college basketball expert picks, predictions and best bets.

The Michigan State Spartans (5-2) and Notre Dame Fighting Irish (5-1) meet Wednesday in South Bend. Tip time at Purcell Pavilion will be at 9:15 p.m. ET (ESPN2). Below, we analyze Tipico Sportsbook’s lines around the Michigan State vs. Notre Dame odds, and make our expert college basketball picks, predictions and bets.

Michigan State snuck by Portland 78-77 in a Sunday game of the Phil Knight Invitational. The favored-by-6.5 Spartans were undone by 14 3-pointers in the win over the Pilots. The against-the-spread (ATS) loss marked MSU’s 3rd in its last 4 games.

The Fighting Irish last played Friday, dropping a 63-51 decision to St. Bonaventure. UND’s 51 points marked a season low.

The game is part of the ACC/Big Ten Challenge. Michigan State and Notre Dame last met on Nov. 28, 2020, when the Spartans topped the Irish 80-70.

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Michigan State at Notre Dame odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:44 p.m. ET.

  • Moneyline: Michigan State -125 (bet $125 to win $100) | Notre Dame +105 (bet $100 to win $105)
  • Against the spread (ATS): Michigan State -1.5 (-115) | Notre Dame +1.5 (-105)
  • Over/Under (O/U): 139.5 (O: -115 | U: -105)

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Michigan State at Notre Dame picks and predictions

Prediction

Michigan State 70, Notre Dame 64

Moneyline

MSU is the superior defensive and rebounding team in this matchup. This game is a jump in class for the Irish, and the Notre Dame shooting numbers (56% effective field goal) are suspect and likely due some regression.

The Spartans’ performances the last few weeks, even in their loss to Alabama last Thursday, spell a team that can be pegged as a 60% proposition in this game. And that makes for value on Michigan State -125. But at the current prices, many bettors may not want to spend 15 cents for a point (vs. the -1.5 ATS action below). So PASS unless prices change.

Against the spread

The Fighting Irish are 1-6 ATS in their last 7 home games. Notre Dame figures to be in a fade spot here.

TAKE MICHIGAN STATE -1.5 (-115).

Over/Under

These teams player slow-tempo ball, and we can expected a game flow not overly infused with turnovers, 2nd-chance points, and free throws.

PLAY THE UNDER 139.5 (-105).

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