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The No. 23 LSU Tigers (3-2. 2-1 SEC) take on the No. 22 Missouri Tigers (5-0, 1-0) in Week 6 of the college football season on Saturday at Faurot Field at Memorial Stadium. Kickoff is scheduled for noon ET (ESPN). Below, we analyze BetMGM Sportsbook’s lines around the LSU vs. Missouri odds, and make our expert college football picks and predictions.
LSU lost 55-49 in a shootout with No. 15 Ole Miss in Week 5, failing to cover as 2.5-point favorites on the road. The Over of 66.5 easily cleared as the Tigers had a 3-game winning streak snapped.
Missouri covered as 14-point road favorites in a 38-21 victory over Vanderbilt while the Over (53) hit. The unbeaten Tigers need 1 win to match last season’s total.
LSU is No. 23 and Missouri is No. 22 in the US LBM Coaches Poll powered by USA Today Sports
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LSU at Missouri odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 7:02 p.m. ET.
- Moneyline (ML): LSU -190 (bet $190 to win $100) | Missouri +160 (bet $100 to win $160)
- Against the spread (ATS): LSU -45 (-110) | Missouri +4.5 (-110)
- Over/Under (O/U): 65.5 (O: -105 | U: -115)
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LSU at Missouri picks and predictions
Prediction
LSU 38, Missouri 34
Moneyline
While LSU is favored on the road, I’ll AVOID wagering here since there’s a chance Missouri can win this game outright at home, so taking LSU at -190 odds isn’t worth the risk.
Against the spread
MISSOURI +4.5 (-110) is the play in this matchup. LSU is giving up 260.2 passing yards per game and its defense has been extremely disappointing this season. Missouri is also 3-2 ATS this season compared to LSU being 2-3 ATS. Once again, it shouldn’t come as a surprise if Missouri wins outright against LSU at home.
Over/Under
With both teams having effective offenses, OVER 64.5 (-110) is how I’d bet on the total. LSU is averaging 44 points per game (7th in the nation) and Missouri is producing 32 points per game (tied for 51st in the nation).
On top of that, LSU is 5-0 to the Over and Missouri is 4-1 to the Over in the first 5 weeks of the season. I’m confident in saying we’ll get a shootout between QB Jayden Daniels and QB Brady Cook.
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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.
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